A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)
Public ClinicalTrials.gov record NCT07795814. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of EDG-15400 in Adults With Symptomatic Heart Failure With Preserved Ejection Fraction
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 2 placebo-controlled study to evaluate the safety and tolerability of different doses of EDG-15400 in adults with heart failure with preserved ejection fraction (HFpEF).
Study identification
- NCT ID
- NCT07795814
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 90 participants
Conditions and interventions
Interventions
Drug
Eligibility (public fields only)
- Age range
- 30 Years to 84 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 24, 2026
- Primary completion
- Nov 30, 2027
- Completion
- Nov 30, 2027
- Last update posted
- Aug 30, 2026
2026 – 2027
United States locations
- U.S. sites
- 25
- U.S. states
- 18
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Local Institution - 156 | Birmingham | Alabama | 35211 | Not yet recruiting |
| Local Institution - 162 | Beverly Hills | California | 90211 | Not yet recruiting |
| Local Institution - 120 | San Diego | California | 92037 | Not yet recruiting |
| Local Institution - 149 | Vista | California | 92081 | Recruiting |
| Local Institution - 153 | Peoria | Illinois | 61636 | Not yet recruiting |
| Local Institution - 166 | Indianapolis | Indiana | 46260 | Not yet recruiting |
| Local Institution - 160 | Cynthiana | Kentucky | 41031 | Not yet recruiting |
| Local Institution - 155 | Houma | Louisiana | 70360 | Not yet recruiting |
| Local Institution - 106 | Baltimore | Maryland | 21287 | Not yet recruiting |
| Local Institution - 158 | Ypsilanti | Michigan | 48197 | Not yet recruiting |
| Local Institution - 164 | Jackson | Mississippi | 39216 | Not yet recruiting |
| Local Institution - 145 | Kansas City | Missouri | 64131 | Not yet recruiting |
| Local Institution - 109 | St Louis | Missouri | 63130 | Not yet recruiting |
| Local Institution - 154 | New York | New York | 10019 | Not yet recruiting |
| Local Institution - 159 | Greensboro | North Carolina | 27401 | Not yet recruiting |
| Local Institution - 129 | Cincinnati | Ohio | 45219 | Not yet recruiting |
| Local Institution - 165 | Mechanicsburg | Pennsylvania | 17050 | Not yet recruiting |
| Local Institution - 124 | Pittsburgh | Pennsylvania | 15213 | Not yet recruiting |
| Local Institution - 142 | Charleston | South Carolina | 29425 | Not yet recruiting |
| Local Institution - 167 | Dallas | Texas | 75390 | Not yet recruiting |
| Local Institution - 151 | Houston | Texas | 77030 | Not yet recruiting |
| Local Institution - 157 | Houston | Texas | 77030 | Not yet recruiting |
| Local Institution - 163 | Houston | Texas | 77030 | Not yet recruiting |
| Local Institution - 143 | Charlottesville | Virginia | 22908 | Not yet recruiting |
| Local Institution - 132 | Seattle | Washington | 98101 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Recently updated Heart Failure With Preserved Ejection Fraction trials
Other public records listing Heart Failure With Preserved Ejection Fraction. Sorted by last update posted; newest first. Not a recommendation.
- NCT07554638: Incretin Therapies in Obesity-related HFpEF Recruiting
- NCT05585125: A Preliminary Study for INFORMED Recruiting
- NCT07123779: HS235 Study in Obese Participants With Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction (HFpEF) Recruiting
- NCT04945707: Impact of Intravenous Iron Repletion On Mechanisms of Exercise InTolerance in HFpEF (IRONMET-HFpEF) Active, not recruiting
- NCT06081543: Ketogenic Diet vs Mixed Diet in Patients With Heart Failure Recruiting
- NCT07686692: IV Iron Therapy for Older Adults With Heart Failure With Preserved Ejection Fraction and Iron Deficiency Not yet recruiting
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07795814, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 30, 2026 · Synced Sep 1, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07795814 live on ClinicalTrials.gov.