Extended Validation of Donor-derived Cell-free DNA in Kidney Transplant Recipients
Public ClinicalTrials.gov record NCT07805343. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Multinational Study to Evaluate the Performance of Donor-derived Cell-free DNA in Detecting Kidney Allograft Rejection Across Context of Use, Populations, and Injury Phenotypes
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a multinational, multi-center, observational cohort study. Kidney allograft rejection is poorly detected by standard-of-care biomarkers. Although dd-cfDNA has been associated with improved rejection detection when added to standard-of-care biomarkers and clinical parameters, little is known about its performance across Banff 2022 rejection phenotypes and injury patterns, in various clinical scenarios and populations, and when measured repeatedly over time.
Study identification
- NCT ID
- NCT07805343
- Recruitment status
- Active, not recruiting
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 5,000 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Not listed
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 14, 2024
- Primary completion
- Nov 30, 2026
- Completion
- Dec 30, 2026
- Last update posted
- Sep 3, 2026
2024 – 2026
United States locations
- U.S. sites
- 14
- U.S. states
- 10
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Department of Medicine, Division of Nephrology, Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA, USA | Los Angeles | California | 90048 | — |
| Department of Pediatrics, Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, California, USA. | Los Angeles | California | 90048 | — |
| Division of Nephrology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA | Los Angeles | California | 90095 | — |
| Department of Nephrology, Tampa General Hospital, Tampa, FL, USA | Tampa | Florida | 33606 | — |
| Division of Pediatric Nephrology, Emory University School of Medicine, Atlanta, GA, USA | Atlanta | Georgia | 30322 | — |
| Division of Nephrology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA | St Louis | Missouri | 63110 | — |
| Division of Pediatric Nephrology, Washington University School of Medicine and St. Louis Children's Hospital, St. Louis, MO, USA | St Louis | Missouri | 63110 | — |
| Division of Nephrology, Weill Cornell Medical College, NewYork-Presbyterian Hospital, New York, NY, USA | New York | New York | 10065 | — |
| Cleveland Clinic, 2050 East 96th Street, Cleveland, OH | Cleveland | Ohio | 44195-0001 | — |
| Department of Medicine, Division of Nephrology, University of Texas Southwestern Medical Center, Dallas, Texas, USA | Dallas | Texas | 75390-8856 | — |
| Transplant Services, Intermountain Medical Center, Murray, UT, USA | Murray | Utah | 84107 | — |
| Division of Nephrology, Department of Medicine, University of Utah Health, Salt Lake City, UT, USA | Salt Lake City | Utah | 84132 | — |
| Division of Nephrology, Virginia Commonwealth University, Richmond, VA, USA | Richmond | Virginia | 23219 | — |
| Department of Medicine, Division of Nephrology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA. | Madison | Wisconsin | 53705 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07805343, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 3, 2026 · Synced Sep 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07805343 live on ClinicalTrials.gov.