Rapid Entrainment and Signal-guided Neuromodulation for Behavioral Health
Public ClinicalTrials.gov record NCT07812987. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Rapid Entrainment and Signal-guided Neuromodulation for Behavioral Health: A Transdiagnostic, Personalized Neuromodulation and Neuroimmune Study to Develop Objective Endpoints and Risk/Durability Profiles for Rapid-Acting Interventions (RESYNC-BH)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
RESYNC-BH is a research study testing a personalized, non-drug brain-and-body treatment program for adults with ongoing behavioral health symptoms such as depression, anxiety, trauma-related symptoms, sleep problems, attention difficulties, or substance-use concerns. Rather than treating participants only according to a psychiatric diagnosis, the study assigns them to one of several treatment approaches based on their symptoms, physiologic measures, and clinical presentation. Treatment may include noninvasive brain or nerve stimulation, light, sound, vibration, regulated breathing, and AIP-informed integrative psychotherapy. The study has two main purposes. First, investigators want to determine whether these personalized treatment combinations can produce rapid and lasting improvements in symptoms, daily functioning, and maladaptive patterns such as avoidance, hypervigilance, rumination, craving, or emotional shutdown. Second, investigators want to identify objective changes in the brain and body that occur before, during, and after treatment. These measures include brain activity, heart rate and heart rate variability, other physiologic signals, cognitive measures, blood biomarkers, and standardized behavioral health questionnaires. The study hypothesis is that meaningful behavioral health improvement is accompanied by measurable changes in brain, body, and behavioral signals, and that early changes in these signals can help predict which treatment approach is most appropriate for an individual, whether treatment is working, whether a person is becoming less stable, and whether improvement is likely to last. The long-term goal is to develop more objective and personalized ways to monitor behavioral health treatment response rather than relying only on symptoms reported at occasional clinic visits.
Study identification
- NCT ID
- NCT07812987
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 240 participants
Conditions and interventions
Conditions
Interventions
- AIP-Informed Integrative Psychotherapy Behavioral
- Transcutaneous Auricular Vagus Nerve Stimulation Device
- Regulated Breathing and Autonomic Regulation Behavioral
- Audiovisual Entrainment Device
- Vibroacoustic Stimulation Device
- Breathwork-Based Auditory Driving Entropy Module (BADEM) Behavioral
- Transcranial Electrical Stimulation Device
Behavioral · Device
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 31, 2026
- Primary completion
- Jun 29, 2028
- Completion
- Dec 30, 2028
- Last update posted
- Sep 9, 2026
2026 – 2028
United States locations
- U.S. sites
- 1
- U.S. states
- 1
- U.S. cities
- 1
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Tactical Mind Research Coalition | Tampa | Florida | 33618 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07812987, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 9, 2026 · Synced Sep 10, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07812987 live on ClinicalTrials.gov.