Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS)
Public ClinicalTrials.gov record NCT07817875. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Efficacy, Safety, and Pharmacokinetics of Tirzepatide Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity: A Phase 3, Randomized, Double-Blind, Placebo-Controlled Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this study, performed under Master Protocol J4M-MC-PWMP (NCT06672549), is to evaluate the efficacy, safety, and pharmacokinetics of tirzepatide as an addition to healthy lifestyle in participants 6 to less than 12 years of age, with obesity. Participation in the study will last about 104 weeks. Participants who have completed the primary 104-week PW02 study (including the 4-week safety follow-up period), will have the opportunity to receive an additional 156 weeks of treatment with tirzepatide as well as continuing the lifestyle intervention.
Study identification
- NCT ID
- NCT07817875
- Recruitment status
- Not yet recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 150 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 6 Years to 11 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 31, 2026
- Primary completion
- Nov 30, 2029
- Completion
- Nov 30, 2032
- Last update posted
- Sep 24, 2026
2026 – 2032
United States locations
- U.S. sites
- 43
- U.S. states
- 24
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arizona | Tucson | Arizona | 85721 | — |
| Loma Linda University School of Medicine | Loma Linda | California | 92354 | — |
| Childrens Hospital of Los Angeles | Los Angeles | California | 90027 | — |
| UCLA Mattel Children's Hospital | Los Angeles | California | 90095 | — |
| Children's Hospital of Orange County | Orange | California | 92868 | — |
| Carey Chronis MD Pediatric, Infant and Adolescent Medicine | Oxnard | California | 93003-5314 | — |
| Children's Hospital Colorado | Colorado Springs | Colorado | 80920-7843 | — |
| Yale New Haven Children's Hospital | New Haven | Connecticut | 06504 | — |
| William A. Shands Hospital at the University of Florida | Gainesville | Florida | 32610-3003 | — |
| Florida Hospital- Center for Pediatric Research | Orlando | Florida | 32803 | — |
| Nemours Children's Health | Orlando | Florida | 32827 | — |
| All Childrens Hospital | St. Petersburg | Florida | 33701 | — |
| Children's Healthcare of Atlanta - Center for Advanced Pediatrics | Atlanta | Georgia | 30329 | — |
| Ann and Robert H Lurie Children's Hospital of Chicago | Chicago | Illinois | 60611 | — |
| University of Illinois at Chicago | Chicago | Illinois | 60612 | — |
| Riley Hospital for Children | Indianapolis | Indiana | 46202 | — |
| Norton Children's Endocrinology | Louisville | Kentucky | 40202 | — |
| Johns Hopkins Children's Center | Baltimore | Maryland | 21287 | — |
| Boston Children's Hospital | Boston | Massachusetts | 02115 | — |
| Helen Devos Childrens' Hospital - PIN | Grand Rapids | Michigan | 49503-2560 | — |
| University of Minnesota Masonic Children's Hospital | Minneapolis | Minnesota | 55454 | — |
| Mayo Clinic - PIN | Rochester | Minnesota | 55905-0001 | — |
| Children's Minnesota Pediatric Endocrinology Clinic & McNeeley Diabetes Center | Saint Paul | Minnesota | 55102-3354 | — |
| Children's Hospital & Medical Center | Omaha | Nebraska | 68114 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| UBMD Pediatrics | Buffalo | New York | 14203 | — |
| UNC Children's Hospital | Chapel Hill | North Carolina | 27514 | — |
| Duke Children's Primary Care | Durham | North Carolina | 27704-2102 | — |
| Lucas Research, Inc | Morehead City | North Carolina | 28557 | — |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Nationwide Children's Hospital | Columbus | Ohio | 43205 | — |
| Oklahoma Childrens Memorial Hospital | Oklahoma City | Oklahoma | 73104-5008 | — |
| Coastal Pediatric Associates | Charleston | South Carolina | 29414 | — |
| Medical University of South Carolina Children Hospital - PIN | Charleston | South Carolina | 29425 | — |
| Vanderbilt Health One Hundred Oaks | Nashville | Tennessee | 37204-3609 | — |
| Dell Children's Medical Center - PIN | Austin | Texas | 78723-3079 | — |
| Driscoll Children's Hospital | Corpus Christi | Texas | 78411 | — |
| McGovern Medical School | Houston | Texas | 77030-1521 | — |
| Texas Childrens Hospital | Houston | Texas | 77030 | — |
| VCU Health - Center for Endocrinology Diabetes and Metabolism | Richmond | Virginia | 23229-3156 | — |
| Seattle Children's Research Institute - Hughes Building - PIN | Seattle | Washington | 98101 | — |
| MultiCare Health System - Mary Bridge Children's Health Center | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 41 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07817875, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 24, 2026 · Synced Sep 26, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07817875 live on ClinicalTrials.gov.