Helping Kentuckians Overcome Depression and Opioid Addiction With Brain Stimulation

ClinicalTrials.gov ID: NCT07842601

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ClinicalTrials.gov public records Last synced Nov 14, 2026, 7:41 AM EST

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Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will compare transcranial magnetic stimulation (TMS) with sham TMS in people with opioid use disorder who are taking buprenorphine and have major depressive disorder with ongoing depressive symptoms. The study will evaluate whether TMS improves depressive symptoms and reduces opioid craving. The study will also assess smoking behaviors, treatment acceptability, and any side effects related to TMS.

Study identification

NCT ID: NCT07842601
Recruitment status: Not yet recruiting
Study type: Interventional
Phase: Not applicable
Lead sponsor: University of Kentucky; Other
Enrollment: 60 participants

Conditions and interventions

Conditions

Interventions

Transcranial Magnetic Stimulation (TMS) Device
Sham Transcranial Magnetic Stimulation (TMS) Device

Device

Eligibility (public fields only)

Age range: 18 Years to 75 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Oct 15, 2026 (Estimated)
Primary completion: Dec 31, 2028 (Estimated)
Completion: Dec 31, 2028 (Estimated)
Last update posted: Sep 25, 2026

2026 – 2028

United States locations

U.S. sites: 1
U.S. states: 1
U.S. cities: 1

Facility	City	State	ZIP	Site status
University of Kentucky	Lexington	Kentucky	40506	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07842601, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Sep 25, 2026 · Synced Nov 14, 2026