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Not yet recruiting Phase 3 Interventional

A Study to Learn About Switching to a Monthly Study Medicine Called Berobenatide (PF-08653944) to Help Keep Weight Off in People With Overweight or Obesity

ClinicalTrials.gov ID: NCT07845500

Public ClinicalTrials.gov record NCT07845500. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 1, 2026, 8:52 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A PHASE 3 STUDY TO EVALUATE THE SWITCH TO MONTHLY BEROBENATIDE FOR MAINTAINING WEIGHT IN ADULTS WHO ARE ON WEEKLY SEMAGLUTIDE OR TIRZEPATIDE (VESPER-SWITCH)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to learn about the safety and effectiveness of berobenatide in adults with overweight or obesity who have already lost weight while taking semaglutide or tirzepatide. The study does not include people with diabetes. Participants will be in the study for about 11 months.

Study identification

NCT ID
NCT07845500
Recruitment status
Not yet recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Pfizer
Industry
Enrollment
660 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 1, 2026 (Estimated)
Primary completion
Feb 16, 2028 (Estimated)
Completion
Feb 16, 2028 (Estimated)
Last update posted
Sep 29, 2026

2026 – 2028

United States locations

U.S. sites
8
U.S. states
8
U.S. cities
8
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35294 —
Suncoast Clinical Research New Port Richey Florida 34652 —
Monroe Biomedical Research Louisville Kentucky 40213 —
Aa Mrc Llc Flint Michigan 48504 —
Clinical Research Professionals Chesterfield Missouri 63005 —
Mercury Street Medical Group, PLLC Butte Montana 59701 —
Accellacare - Wilmington Wilmington North Carolina 28401 —
Velocity Clinical Research, Mt. Auburn Cincinnati Ohio 45219 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07845500, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 29, 2026 · Synced Oct 1, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT07845500 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →