A Study to Evaluate the Immune Response and Safety of a Vaccine Against Influenza in Adults 18-64 Years of Age
Public ClinicalTrials.gov record NCT07851246. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Observer-Blind, Controlled Study to Evaluate the Immunogenicity, Reactogenicity and Safety of an mRNA-based Seasonal Influenza Vaccine, in Adults 18-64 Years of Age
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This clinical trial will study an investigational seasonal influenza vaccine in adults 18 to 64 years of age. The vaccine is based on messenger ribonucleic acid, also called mRNA. The main goals of the study are to learn how well the vaccine helps the body make an immune response against influenza and what medical problems participants may have after vaccination. Researchers will also compare immune responses in adults 18 to 64 years of age from this study, with immune responses in adults 65 years of age and older from another study. Participants will receive 1 injection into the upper arm muscle and will be followed for about 6 months.
Study identification
- NCT ID
- NCT07851246
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 3,000 participants
Conditions and interventions
Conditions
Interventions
- mRNA Seasonal Flu vaccine Biological
- Comparator 1 Biological
- Comparator 2 Biological
Biological
Eligibility (public fields only)
- Age range
- 18 Years to 64 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 1, 2026 (Actual)
- Primary completion
- Jul 9, 2027 (Estimated)
- Completion
- Jul 9, 2027 (Estimated)
- Last update posted
- Oct 9, 2026
2026 – 2027
United States locations
- U.S. sites
- 12
- U.S. states
- 9
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| GSK Investigational Site | Glendale | Arizona | 85308 | Recruiting |
| GSK Investigational Site | Tucson | Arizona | 85711 | Recruiting |
| GSK Investigational Site | San Diego | California | 92123 | Recruiting |
| GSK Investigational Site | Miami | Florida | 33186 | Recruiting |
| GSK Investigational Site | Miami Lakes | Florida | 33016 | Recruiting |
| GSK Investigational Site | Meridian | Idaho | 83642-3154 | Recruiting |
| GSK Investigational Site | Valparaiso | Indiana | 46383 | Recruiting |
| GSK Investigational Site | Lenexa | Kansas | 66219 | Recruiting |
| GSK Investigational Site | Hartsdale | New York | 10530 | Recruiting |
| GSK Investigational Site | Spartanburg | South Carolina | 29303 | Recruiting |
| GSK Investigational Site | DeSoto | Texas | 75115 | Recruiting |
| GSK Investigational Site | Fort Worth | Texas | 76135 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07851246, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 9, 2026 · Synced Oct 12, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07851246 live on ClinicalTrials.gov.