Improving Implementation of Guideline-Recommended LDL-C Management in High-Risk Cardiovascular Patients
Public ClinicalTrials.gov record NCT07883564. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Improving Implementation of Guideline-Recommended LDL-C Management in High-Risk Cardiovascular Patients: A Multilevel Implementation Science Study
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The goal of this observational study is to learn whether implementing evidence-based strategies in cardiology practices can improve guideline-recommended low-density lipoprotein cholesterol (LDL-C) management in adults at high risk for cardiovascular disease. Participants include adults with a recent myocardial infarction (heart attack), coronary stent placement, percutaneous coronary intervention (PCI), ischemic heart disease, or a coronary artery calcium (CAC) score of 300 or higher. The main questions it aims to answer are: * Do implementation strategies increase the proportion of patients who receive LDL-C testing, have lipid-lowering therapy (LLT) started or intensified, and achieve guideline-recommended LDL-C goals within 6 months of their index visit? * Do implementation strategies improve cardiovascular risk factor management and LDL-C goal attainment at 3 and 12 months after the index visit? * How acceptable, feasible, and effective are these implementation strategies for patients, clinicians, and healthcare sites? Researchers will compare outcomes among patients receiving care after implementation of the study strategies with outcomes from a retrospective cohort of similar patients treated before the strategies were introduced. Participants will: * Receive usual cardiovascular care from their healthcare providers. * Be cared for at sites implementing one or more evidence-based strategies, which may include clinician performance scorecards, electronic health record best practice alerts, clinician education, patient education, and/or follow-up through an Advanced Practice Provider (APP) care pathway. * Attend routine follow-up visits and undergo LDL-C testing and other cardiovascular assessments as part of standard clinical care. * Have information from their electronic health records reviewed, including laboratory results, medications, blood pressure measurements, smoking status, and cardiovascular outcomes. * Complete surveys about their experiences with the implementation strategies, if applicable. * Be followed for up to 12 months after their index visit.
Study identification
- NCT ID
- NCT07883564
- Recruitment status
- Not yet recruiting
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 2,500 participants
Conditions and interventions
Conditions
Interventions
Not listed
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 2026 (Estimated)
- Primary completion
- Mar 2028 (Estimated)
- Completion
- Oct 2028 (Estimated)
- Last update posted
- Oct 20, 2026
2026 – 2028
United States locations
- U.S. sites
- 5
- U.S. states
- 4
- U.S. cities
- 5
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clearwater Cardiovascular Consultants | Clearwater | Florida | 33756 | — |
| First Coast Cardiovascular Institute | Jacksonville | Florida | 32216 | — |
| Cardiovascular Institute of the South | Houma | Louisiana | 70360 | — |
| Capital Cardiology Associates | Albany | New York | 12211 | — |
| Cardiology Consultants of Philadelphia | Philadelphia | Pennsylvania | 19107 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07883564, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 20, 2026 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07883564 live on ClinicalTrials.gov.