A Study to Investigate the Effect of LY4086940 Versus Placebo in Participants With Obesity or Overweight and Without Type 2 Diabetes
Public ClinicalTrials.gov record NCT07890376. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Parallel-Group, Double-Blind Study to Investigate Weight Management With LY4086940 Compared With Placebo in Adult Participants With Obesity or Overweight and Without Type 2 Diabetes
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study, performed under the master protocol W8M-MC- CWMM (NCT06143956), is to evaluate the efficacy and safety of LY4086940 compared with placebo in participants without type 2 diabetes who have obesity or who have overweight with a weight-related health condition. Participation in the study will last about 58 weeks.
Study identification
- NCT ID
- NCT07890376
- Recruitment status
- Not yet recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 460 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 2026 (Estimated)
- Primary completion
- Jan 2028 (Estimated)
- Completion
- Jun 2028 (Estimated)
- Last update posted
- Oct 22, 2026
2026 – 2028
United States locations
- U.S. sites
- 39
- U.S. states
- 20
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The Institute for Liver Health II dba Arizona Clinical Trials - Mesa | Chandler | Arizona | 85225 | — |
| Headlands Research - Scottsdale | Scottsdale | Arizona | 85260 | — |
| The Institute for Liver Health II dba Arizona Liver Health-Tucson | Tucson | Arizona | 85712 | — |
| NorCal Medical Research, Inc | Greenbrae | California | 94904 | — |
| Velocity Clinical Research, Huntington Park | Huntington Park | California | 90255 | — |
| Peninsula Research Associates | Rolling Hills Estates | California | 90274 | — |
| Diablo Clinical Research, Inc. | Walnut Creek | California | 94598 | — |
| Stamford Therapeutics Consortium | Stamford | Connecticut | 06905 | — |
| New Horizon Research Center | Miami | Florida | 33165 | — |
| Indago Research & Health Center, Inc | Miami Lakes | Florida | 33016 | — |
| Suncoast Clinical Research, Inc. | New Port Richey | Florida | 34652 | — |
| Charter Research - Winter Park | Orlando | Florida | 32803 | — |
| Charter Research - Lady Lake | The Villages | Florida | 32162 | — |
| Medical Research Partners | Ammon | Idaho | 83406 | — |
| Great Lakes Clinical Trials - Ravenswood | Chicago | Illinois | 60640 | — |
| Iowa Diabetes and Endocrinology Research Center | West Des Moines | Iowa | 50266 | — |
| Cotton O'Neil Diabetes & Endocrinology | Topeka | Kansas | 66606 | — |
| Knownwell | Needham | Massachusetts | 02492 | — |
| Lucida Clinical Trials | New Bedford | Massachusetts | 02740 | — |
| Headlands Research - Detroit | Southfield | Michigan | 48034 | — |
| Arcturus Healthcare , PLC, Troy Internal Medicine Research Division | Troy | Michigan | 48098 | — |
| StudyMetrix Research | City of Saint Peters | Missouri | 63303 | — |
| Clinvest Headlands Llc | Springfield | Missouri | 65807 | — |
| Las Vegas Medical Research | Las Vegas | Nevada | 89128 | — |
| Dent Neurologic Institute | Amherst | New York | 14226 | — |
| Rochester Clinical Research, LLC | Rochester | New York | 14609 | — |
| Monroe Biomedical Research | Monroe | North Carolina | 28112 | — |
| Lucas Research, Inc | Morehead City | North Carolina | 28557 | — |
| Lucas Research, Inc. | New Bern | North Carolina | 28562 | — |
| CTI Clinical Research Center | Cincinnati | Ohio | 45212 | — |
| Tribe Clinical Research, LLC | Greenville | South Carolina | 29607 | — |
| Quality Medical Research | Nashville | Tennessee | 37211 | — |
| IMA Clinical Research Austin | Austin | Texas | 78745 | — |
| Velocity Clinical Research, Dallas | Dallas | Texas | 75230 | — |
| FutureSearch Trials of Dallas | Dallas | Texas | 75251 | — |
| Endeavor Clinical Trials | San Antonio | Texas | 78240 | — |
| Texas Valley Clinical Research | Weslaco | Texas | 78596 | — |
| Sovah Clinical Research-River District | Danville | Virginia | 24541 | — |
| Central Washington Health Services Association d/b/a Confluence Health | Wenatchee | Washington | 98801 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07890376, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 22, 2026 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07890376 live on ClinicalTrials.gov.