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Recruiting Phase 1 Interventional

Comparing the Extent to Which Maridebart Cafraglutide is Made Available in the Body of Participants Living With Overweight or Obesity After Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA)

ClinicalTrials.gov ID: NCT07908316

Public ClinicalTrials.gov record NCT07908316. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Nov 6, 2026, 6:11 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1, Randomized, Double-blind, Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Maridebart Cafraglutide After Switching From Glucagon-like Peptide-1 Receptor Agonists in Participants Living With Overweight or Obesity

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary purpose of the study is to assess the pharmacokinetics of maridebart cafraglutode after switching from weekly GLP-1RA in participants living with overweight or obesity.

Study identification

NCT ID
NCT07908316
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 1
Lead sponsor
Amgen
Industry
Enrollment
180 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 70 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 13, 2026 (Estimated)
Primary completion
Dec 20, 2027 (Estimated)
Completion
Feb 25, 2028 (Estimated)
Last update posted
Nov 2, 2026

2026 – 2028

United States locations

U.S. sites
9
U.S. states
7
U.S. cities
9
Facility City State ZIP Site status
Arizona Research Center Phoenix Arizona 85053 Recruiting
Catalina Research Institute LLC (CRI) - Montclair Montclair California 91763 Recruiting
Fortrea Clinical Research Unit - Daytona Beach Daytona Beach Florida 32117-5116 Recruiting
AGA Clinical Trials Hialeah Florida 33012-3437 Recruiting
K2 Medical Research Orlando Maitland Florida 32751-7240 Recruiting
The Alliance for Multispecialty Research - Lexington Lexington Kentucky 40509 Recruiting
Alliance for Multispecialty Research - Knoxville Knoxville Tennessee 37920-1534 Recruiting
Fortrea Clinical Research Unit - Dallas Dallas Texas 75247-4968 Recruiting
Fortrea Clinical Research Unit Inc. - Madison Madison Wisconsin 53704-2526 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07908316, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 2, 2026 · Synced Nov 6, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT07908316 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →