PET Imaging of the sigma1 Receptor in Healthy Adults
Public ClinicalTrials.gov record NCT07915323. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
Evaluation of (S)-[18F] FBFP and (R)-[18F] FBFP as a Radioligands for Positron Emission Tomography Imaging of the Sigma-1 Receptor
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Evaluate (S)-\[18F\]FBFP and (R)-\[18F\]FBFP, sigma-1 radiotracers, in humans, to characterize their pharmacokinetic, metabolic, and in vivo binding profiles, assess feasibility for quantitative kinetic modeling analysis of imaging data, and determine the reliability and reproducibility of kinetic and binding parameters. Assess specific binding levels of (S)-\[18F\]FBFP or (R)-\[18F\]FBFP by conducting test-block studies in humans.
Study identification
- NCT ID
- NCT07915323
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 30 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 60 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 1, 2025 (Actual)
- Primary completion
- May 31, 2028 (Estimated)
- Completion
- May 31, 2028 (Estimated)
- Last update posted
- Nov 4, 2026
2025 – 2028
United States locations
- U.S. sites
- 1
- U.S. states
- 1
- U.S. cities
- 1
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Yale University PET Center | New Haven | Connecticut | 06519 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07915323, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 4, 2026 · Synced Nov 5, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07915323 live on ClinicalTrials.gov.