Non-invasive Spinal Stimulation for Gait in Genetic Spasticity

ClinicalTrials.gov ID: NCT07930481

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 8:01 AM EST

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Official title

Non-invasive Electrical Spinal Cord Stimulation to Improve Locomotor Function in Patients With Genetic Causes of Spasticity

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This trial is a double-blind, crossover, sham-controlled pilot study to evaluate the feasibility, safety, and preliminary efficacy of repeated transcutaneous spinal cord stimulation (tSCS) over the lower thoracic and upper lumbar spinal segments in adults with hereditary spastic paraplegias (HSPs) and other genetic causes of spasticity. The investigators will recruit four people with hereditary lower extremity spasticity who are able to ambulate with or without assistive devices to participate in the trial. The investigators will assess a range of outcome measures to evaluate tSCS in this patient population and to inform the design of a larger study.

Study identification

NCT ID: NCT07930481
Recruitment status: Enrolling by invitation
Study type: Interventional
Phase: Not applicable
Lead sponsor: University of Washington; Other
Enrollment: 4 participants

Conditions and interventions

Conditions

Interventions

Transcutaneous spinal cord stimulation Device
Sham transcutaneous spinal cord stimulation Device

Device

Eligibility (public fields only)

Age range: 18 Years to 70 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Nov 2026 (Estimated)
Primary completion: Jun 2027 (Estimated)
Completion: Nov 2027 (Estimated)
Last update posted: Nov 12, 2026

2026 – 2027

United States locations

U.S. sites: 1
U.S. states: 1
U.S. cities: 1

Facility	City	State	ZIP	Site status
John Wallace Hall, Amplify Movement and Performance Laboratory	Seattle	Washington	98105	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07930481, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Nov 12, 2026 · Synced Nov 15, 2026