- Conditions
- Adrenal Gland Tumors, Bladder Cancer, Breast Cancer, Cervical Cancers, Colorectal Cancer, Esophageal Cancer, Gastric Cancer, Head and Neck Cancers, Hepatocellular Carcinoma, Lung Cancer, Melanoma, Ovarian Cancer, Pancreatic Cancer, Prostate Cancer, Renal Cell Carcinoma, Sarcoma
- Interventions
- IDOV-Immune (oncolytic vaccinia virus)
- Biological
- Lead sponsor
- ViroMissile, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 78 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 3
- States / cities
- St Louis, Missouri • Houston, Texas • San Antonio, Texas
Colorectal Cancer clinical trials
Directory of U.S. ClinicalTrials.gov public records for Colorectal Cancer. Browse Colorectal Cancer recruiting trials, filter by phase, sponsor, location, or intervention, and open the official ClinicalTrials.gov study record for each result.
By Clinical Trials Finder Guidance last reviewed June 10, 2026 Data synced October 27, 2026 Report an issue
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
The live registry is temporarily unavailable. These stored records may be incomplete or out of date. Check the official record for current status and contact information.
How Colorectal Cancer studies are organized in the registry
Records may be registered under “colorectal,” “colon,” or “rectal” cancer — the three terms overlap but are not interchangeable in search, so check more than one if your interest spans them. Molecular labels (MSI-high, KRAS, BRAF) and the abbreviation mCRC for metastatic disease appear frequently in titles.
These describe how studies tend to be titled and grouped on ClinicalTrials.gov — they are search vocabulary, not medical guidance.
Stored official records
Open in full search- Conditions
- Anastomotic Leakage, Colorectal Cancer, Colorectal Surgery, Ileostomy - Stoma, Rectal/Anal
- Interventions
- COLO BT™, Stoma Creation
- Device · Other
- Lead sponsor
- JSR Medical Co., Ltd.
- Industry
- Eligibility
- 19 Years to 80 Years
- Enrollment
- 256 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2028
- U.S. locations
- 3
- States / cities
- Buffalo, New York • Hershey, Pennsylvania • Houston, Texas
- Conditions
- ColoRectal Cancer and Inflammatory Bowel Disease
- Interventions
- Enhanced Recovery protocol
- Other
- Lead sponsor
- University of Arkansas
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2028
- U.S. locations
- 1
- States / cities
- Little Rock, Arkansas
- Conditions
- Adenoma, Colorectal Cancer (Diagnosis)
- Interventions
- S-Adenosylmethionine (SAMe)
- Drug
- Lead sponsor
- Jun Gong, MD
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Colorectal Cancer, Minimal Residual Disease
- Interventions
- Cetuximab, Cyclophosphamide, Fludarabine Phosphate, Lymphodepleting Chemotherapy, Rimiducid (AP1903), TROP2-CAR-NK Cells
- Drug · Procedure
- Lead sponsor
- M.D. Anderson Cancer Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2029
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Colorectal Cancer (CRC), Head and Neck Squamous Cell Carcinoma (HNSCC), Malignant Solid Tumor, Melanoma, Non-Small Cell Lung Cancer (NSCLC), Pancreatic Ductal Adenocarcinoma (PDAC)
- Interventions
- 5-FU, Carboplatin, Cisplatin, GEN1042, Gemcitabine, Nab paclitaxel, Paclitaxel, Pembrolizumab, Pemetrexed
- Drug · Biological
- Lead sponsor
- Genmab
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 350 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2027
- U.S. locations
- 23
- States / cities
- Anchorage, Alaska • Los Alamitos, California • San Diego, California + 19 more
- Conditions
- Advanced Solid Tumors, CRC, Colorectal Cancer (CRC), Metastatic Solid Tumors, NSCLC, Non-small Cell Lung Cancer (NSCLC)
- Interventions
- Carboplatin/Cisplatin + Pemetrexed (Cohort B2 Only), Carboplatin/Cisplatin + Pemetrexed (Dose Expansion Only), Daraxonrasib, Daraxonrasib (Cohort B1 only), Elironrasib, Ivonescimab, Zoldonrasib, cetuximab (Cohort C2 Only)
- Drug
- Lead sponsor
- Revolution Medicines, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 370 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 8
- States / cities
- Los Angeles, California • Norwich, Connecticut • Saint Paul, Minnesota + 5 more
- Conditions
- Breast Cancer, Breast Cancer Stage III, Breast Cancer Stage IV, Colorectal Cancer, Colorectal Cancer Stage III, Colorectal Cancer Stage IV, Prostate Cancer, Prostate Cancer Stage III, Prostate Cancer Stage IV, Thyroid Cancer, Thyroid Cancer Stage III, Thyroid Cancer Stage IV
- Interventions
- Meaning-Centered Psychotherapy for Latinos /MCP-L
- Behavioral
- Lead sponsor
- Memorial Sloan Kettering Cancer Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Colorectal Cancer, Endometrial Cancer, Hereditary Cancer Syndromes
- Interventions
- Not listed
- Lead sponsor
- Weill Medical College of Cornell University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,120 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2027
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Biliary Tract Cancer (BTC), Cholangiocarcinoma, Colorectal Cancer, GEJ Adenocarcinoma, Gall Bladder Cancer, Gastric Cancer (GC), Gastro Esophageal Junctional Cancer, PDAC - Pancreatic Ductal Adenocarcinoma
- Interventions
- IKS04 antibody drug conjugate ADC + Isumab04 monoclonal antibody
- Drug
- Lead sponsor
- Iksuda Therapeutics Ltd.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 4
- States / cities
- Los Angeles, California • Boston, Massachusetts • Nashville, Tennessee + 1 more
- Conditions
- Colorectal Cancer, Pancreatic Cancer
- Interventions
- Balstilimab, Botensilimab, KRAS Vaccine with Poly-ICLC adjuvant
- Drug
- Lead sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 54 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2030
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Advanced Malignant Solid Neoplasm, Advanced Microsatellite Stable Colorectal Carcinoma, Hematopoietic and Lymphatic System Neoplasm, Metastatic Malignant Solid Neoplasm, Metastatic Microsatellite Stable Colorectal Carcinoma, Stage III Colorectal Cancer AJCC v8, Stage IV Colorectal Cancer AJCC v8
- Interventions
- Biopsy Procedure, Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging, Temozolomide, Tuvusertib
- Procedure · Drug
- Lead sponsor
- National Cancer Institute (NCI)
- NIH
- Eligibility
- 18 Years and older
- Enrollment
- 42 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 23
- States / cities
- Irvine, California • La Jolla, California • Orange, California + 17 more
About this Colorectal Cancer clinical trials directory page
- What this page lists
- U.S. ClinicalTrials.gov public records that list Colorectal Cancer as a study condition, including recruiting, not yet recruiting, and active not recruiting trials across phase 1, phase 2, and phase 3.
- How to narrow results
- Use the filters above to scope by intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, age, or NCT ID within Colorectal Cancer.
- Where the data comes from
- Records are sourced from the official ClinicalTrials.gov public API. Each result links back to the official study page, which is the source of truth for eligibility, enrollment, and contact information.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, ranking of trials by quality, or AI-generated medical summaries.
Related: all condition pages, browse by drug or therapy, browse by U.S. city, browse by sponsor, or open the full search for Colorectal Cancer.