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Obesity clinical trials

Directory of U.S. ClinicalTrials.gov public records for Obesity. Browse Obesity recruiting trials, filter by phase, sponsor, location, or intervention, and open the official ClinicalTrials.gov study record for each result.

By Clinical Trials Finder Guidance last reviewed June 10, 2026 Data synced October 31, 2026 Report an issue

ClinicalTrials.gov public records Last synced Oct 31, 2026, 5:16 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials
6025
Shown on this page
12
Current sort
Recently updated
Condition scope
Obesity
Additional filters apply within this condition.

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

How Obesity studies are organized in the registry

Obesity research spreads across several neighboring registry terms — “overweight,” “weight loss,” and “metabolic syndrome” all label closely related studies — so checking more than one term gives a fuller picture. The portfolio includes many behavioral and lifestyle studies alongside drug trials, which makes the study-type filter (interventional vs. observational) more informative than usual.

Terms that often appear in related listings
weight loss overweight metabolic syndrome bariatric

These describe how studies tend to be titled and grouped on ClinicalTrials.gov — they are search vocabulary, not medical guidance.

Filter and sort this condition

These controls apply only within Obesity. Default order is Recently updated. Add location, sponsor, treatment, or recruitment status to narrow this condition page further.

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Showing 481–492 of 6,025 matching trials for Obesity.
Live ClinicalTrials.gov results.
Local aggregate panels are unavailable or hidden for filtered views. The result list above identifies its data source.

Live official records

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Not yet recruiting Not applicable Interventional

A Randomized Controlled Trial of Prepared vs. Unprepared Food

NCT07800182
View directory record Official record
Conditions
Pregnant Patients at Risk of Gestational Diabetes
Interventions
Prepared meals, Unprepared Pantry/Produce box
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 31, 2026, 5:16 AM EDT
Recruiting Phase 3 Interventional

Early Reinitiation of Semaglutide Post-Sleeve Gastrectomy in Youth

NCT06934655
View directory record Official record
Conditions
Pediatric Obesity, Metabolic and Bariatric Surgery, Semaglutide
Interventions
Semaglutide 2.4 mg
Drug
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
12 Years to 18 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2033
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 31, 2026, 5:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project REST: Regulation of Eating and Sleep Topography

NCT04057716
View directory record Official record
Conditions
Obesity, Childhood, Binge Eating, Sleep, Self-regulation
Interventions
Sleep restriction, Sleep extension
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
8 Years to 12 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 31, 2026, 5:16 AM EDT
Recruiting Phase 1Phase 2 Interventional

The Effect of SGLT2 Inhibition on Adipose Inflammation and Endothelial Function

NCT05972564
View directory record Official record
Conditions
Obesity, Metabolic Syndrome
Interventions
Empagliflozin 25 MG, Placebo
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 31, 2026, 5:16 AM EDT
Completed Not applicable Interventional Results available

Childcare Healthy Beverage Access, Food and Beverage Intake, and Obesity

NCT05112185
View directory record Official record
Conditions
Obesity
Interventions
Healthy Drinks, Healthy Futures
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
2 Years to 105 Years
Enrollment
1,034 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 31, 2026, 5:16 AM EDT
Not yet recruiting Not applicable Interventional

Pilot Study of Endoscopic Sleeve Gastroplasty for Obese Patients With Heart Failure and Preserved Ejection Fraction

NCT07798219
View directory record Official record
Conditions
Obesity (BMI>30), Heart Failure With Preserved Ejection Fraction (HFPEF)
Interventions
Endoscopic sleeve gastroplasty (ESG)
Procedure
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
22 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 31, 2026, 5:16 AM EDT
Active, not recruiting Not applicable Interventional

Telenutrition for Individuals With SCI

NCT05468437
View directory record Official record
Conditions
Spinal Cord Injuries, Obesity, Cardiometabolic Syndrome
Interventions
Telenutrition
Behavioral
Lead sponsor
Santa Clara Valley Health & Hospital System
Other
Eligibility
20 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 31, 2026, 5:16 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

HealthyTogether: RCT of a Dyadic Weight Management Intervention

NCT06619041
View directory record Official record
Conditions
Obesity, Overweight
Interventions
HealthyTogether
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
2
States / cities
Aurora, Colorado • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 31, 2026, 5:16 AM EDT
Active, not recruiting Phase 2 Interventional Accepts healthy volunteers

A Study to Test if Trevogrumab or Trevogrumab With Garetosmab When Taken With Semaglutide is Safe and How Well They Work in Adult Patients With Obesity for Weight Loss, Fat Loss, and Lean Mass Preservation

NCT06299098
View directory record Official record
Conditions
Obesity
Interventions
Trevogrumab-Part A, Trevogrumab-Part B and Part C, Garetosmab, Semaglutide, Matching Placebo-Part A, Matching Placebo-Trevogrumab, Matching Placebo-Garetosmab
Drug
Lead sponsor
Regeneron Pharmaceuticals
Industry
Eligibility
18 Years to 80 Years
Enrollment
1,005 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
58
States / cities
Anniston, Alabama • Cullman, Alabama • Phoenix, Arizona + 51 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 31, 2026, 5:16 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Healthy Children, Healthy Communities: Effectiveness of a Multilevel Rural Community Engagement Model for Improving Children's Dietary Intake in Family Child Care Homes

NCT07160530
View directory record Official record
Conditions
Childhood Obesity Pevention, Diet Quality, Feeding Behaviors, Health Behavior Change, Rural Health
Interventions
EAT Family Style, Better Kid Care
Behavioral
Lead sponsor
University of Nebraska Lincoln
Other
Eligibility
3 Years and older
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 31, 2026, 5:16 AM EDT
Active, not recruiting Not applicable Interventional

Effect of Weight Loss on Urinary Oxalate Excretion in Obese Calcium Oxalate Kidney Stone Formers

NCT04633811
View directory record Official record
Conditions
Kidney Stone
Interventions
Low Oxalate Diet before Weight Loss, Oral load of oxalate and sucralose before Weight Loss, Optifast VLCD Program, Optifast VLCD Transition Phase, Low Oxalate Diet after Weight Loss, Oral load of oxalate and sucralose after Weight Loss
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 31, 2026, 5:16 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

BRIDGE & Friends Trial

NCT07798557
View directory record Official record
Conditions
Obesity & Overweight
Interventions
Social Network Curriculum
Behavioral
Lead sponsor
University of Illinois Chicago
Other
Eligibility
50 Years to 79 Years
Enrollment
532 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 31, 2026, 5:16 AM EDT

About this Obesity clinical trials directory page

What this page lists
U.S. ClinicalTrials.gov public records that list Obesity as a study condition, including recruiting, not yet recruiting, and active not recruiting trials across phase 1, phase 2, and phase 3.
How to narrow results
Use the filters above to scope by intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, age, or NCT ID within Obesity.
Where the data comes from
Records are sourced from the official ClinicalTrials.gov public API. Each result links back to the official study page, which is the source of truth for eligibility, enrollment, and contact information.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, ranking of trials by quality, or AI-generated medical summaries.

Related: all condition pages, browse by drug or therapy, browse by U.S. city, browse by sponsor, or open the full search for Obesity.