Condition Directory

Obesity clinical trials

Directory of U.S. ClinicalTrials.gov public records for Obesity. Browse Obesity recruiting trials, filter by phase, sponsor, location, or intervention, and open the official ClinicalTrials.gov study record for each result.

By Clinical Trials Finder Guidance last reviewed June 10, 2026 Data synced November 3, 2026 Report an issue

ClinicalTrials.gov public records Last synced Nov 3, 2026, 6:00 AM EST

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

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How Obesity studies are organized in the registry

Obesity research spreads across several neighboring registry terms — “overweight,” “weight loss,” and “metabolic syndrome” all label closely related studies — so checking more than one term gives a fuller picture. The portfolio includes many behavioral and lifestyle studies alongside drug trials, which makes the study-type filter (interventional vs. observational) more informative than usual.

Terms that often appear in related listings

weight loss overweight metabolic syndrome bariatric

These describe how studies tend to be titled and grouped on ClinicalTrials.gov — they are search vocabulary, not medical guidance.

Showing 985–996 of 6,028 matching trials for Obesity.

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Local aggregate panels are unavailable or hidden for filtered views. The result list above identifies its data source.

Live official records

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Conditions: Respiratory Failure, Obesity
Interventions: transpulmonary pressure guided positive end expiratory pressure, standard positive end expiratory pressure; Other
Lead sponsor: University of Mississippi Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Jackson, Mississippi

Conditions: Obesity, Overweight
Interventions: LY3549492, Placebo; Drug
Lead sponsor: Eli Lilly and Company; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 288 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 49
States / cities: Chandler, Arizona • Phoenix, Arizona • Scottsdale, Arizona + 43 more

Conditions: Healthy Aging, Overweight and Obesity
Interventions: monounsaturated fatty acids (MUFA) peanut meal; Behavioral
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 55 Years and older
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 2
States / cities: New Brunswick, New Jersey

Conditions: Insulin Resistance, Insulin Sensitivity, Obesity, Inflammation
Interventions: Not listed
Lead sponsor: Stanford University; Other
Eligibility: 30 Years to 65 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2026
U.S. locations: 1
States / cities: Stanford, California

Conditions: Psoriatic Arthritis, Obesity
Interventions: Ixekizumab, Tirzepatide; Drug
Lead sponsor: Eli Lilly and Company; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 279 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 81
States / cities: Avondale, Arizona • Chandler, Arizona • Flagstaff, Arizona + 75 more

Conditions: Type 1 Diabetes, Eating Behavior, Adolescent Obesity
Interventions: T1DAL Program; Behavioral
Lead sponsor: The Miriam Hospital; Other
Eligibility: 13 Years to 18 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Obesity, Inflammation, Dietary Fat
Interventions: Low Fat Diet (LFD), High Fat Diet (HFD); Other
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 50 Years to 79 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Obesity
Interventions: 300 mg SC, 500 mg SC, Placebo; Dietary Supplement
Lead sponsor: Rutgers University; Other
Eligibility: 20 Years to 59 Years
Enrollment: 51 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: New Brunswick, New Jersey

Conditions: Obesity
Interventions: Survodutide, Semaglutide; Drug
Lead sponsor: Boehringer Ingelheim; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: Orlando, Florida • Baton Rouge, Louisiana

Conditions: Prader-Willi Syndrome
Interventions: Pitolisant oral tablets, Placebo oral tablet; Drug
Lead sponsor: Harmony Biosciences Management, Inc.; Industry
Eligibility: 6 Years to 65 Years
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 13
States / cities: San Diego, California • San Ramon, California • Santa Monica, California + 10 more

Conditions: Pregnancy
Interventions: Not listed
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 0 Years to 39 Years
Enrollment: 140 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Health Behavior, Obesity, Motor Activity
Interventions: Mentoring to be Active with Accelerometers, Planning to be Active with Accelerometers; Behavioral
Lead sponsor: Ohio State University; Other
Eligibility: 14 Years to 64 Years
Enrollment: 571 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 20
States / cities: Bidwell, Ohio • Chillicothe, Ohio • Coal Grove, Ohio + 13 more

About this Obesity clinical trials directory page

What this page lists: U.S. ClinicalTrials.gov public records that list Obesity as a study condition, including recruiting, not yet recruiting, and active not recruiting trials across phase 1, phase 2, and phase 3.
How to narrow results: Use the filters above to scope by intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, age, or NCT ID within Obesity.
Where the data comes from: Records are sourced from the official ClinicalTrials.gov public API. Each result links back to the official study page, which is the source of truth for eligibility, enrollment, and contact information.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, ranking of trials by quality, or AI-generated medical summaries.

Obesity clinical trials

How Obesity studies are organized in the registry

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Live official records

Transpulmonary Pressure Guided Mechanical Ventilation Weaning in Obesity

A Study to Investigate Weight Management With LY3549492 Compared With Placebo in Adult Participants With Obesity or Overweight

Postprandial Inflammation and Nuts (PIN) in Older Adults

Adaptive Immune Response in Visceral and Subcutaneous Fat: Role in Human Insulin Resistance

Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Psoriatic Arthritis and Obesity or Overweight

Type 1 Diabetes Adolescents for Healthier Lifestyles Study

Lean and Obese: Dietary Inflammation

Satiety and Glucose Indices in Adults

A Study to Test Whether Survodutide Improves How the Body Uses Energy and Breaks Down Fat in People With Obesity

A Phase 2 Study to Evaluate the Safety and Efficacy of Pitolisant in Patients With Prader-Willi Syndrome, Followed by an Open Label Extension

The Early and Late Contribution of Fasting and Postprandial Triglycerides on Newborn Subcutaneous and Intrahepatic Fat in Pregnancy

A Skills-based RCT for Physical Activity Using Peer Mentors

About this Obesity clinical trials directory page