Condition Directory

Parkinson's Disease clinical trials

Directory of U.S. ClinicalTrials.gov public records for Parkinson's Disease. Browse Parkinson's Disease recruiting trials, filter by phase, sponsor, location, or intervention, and open the official ClinicalTrials.gov study record for each result.

By Clinical Trials Finder Guidance last reviewed June 10, 2026 Data synced October 4, 2026 Report an issue

ClinicalTrials.gov public records Last synced Oct 4, 2026, 11:17 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials

256

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How Parkinson's Disease studies are organized in the registry

Records generally use the registry spelling “Parkinson disease.” The portfolio mixes drug studies with a high share of device, exercise, and rehabilitation research, so the study-type filter is unusually useful here. Disease-stage language (“early,” “advanced,” “levodopa-treated”) commonly appears in titles.

Terms that often appear in related listings

early Parkinson deep brain stimulation levodopa gait

These describe how studies tend to be titled and grouped on ClinicalTrials.gov — they are search vocabulary, not medical guidance.

Showing 49–60 of 256 matching trials for Parkinson's Disease.

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Conditions: Parkinson Disease, Dyskinesia, Drug-Induced
Interventions: Intravenous Infusion; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 50 Years and older
Enrollment: 93 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 3
States / cities: Portland, Oregon • Seattle, Washington

Conditions: Parkinson Disease
Interventions: Tavapadon, Placebo; Drug
Lead sponsor: AbbVie; Industry
Eligibility: 40 Years to 80 Years
Enrollment: 507 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 54
States / cities: Phoenix, Arizona • Little Rock, Arkansas • Fountain Valley, California + 48 more

Conditions: Parkinson Disease, Tremor
Interventions: Istradefylline Pill; Drug
Lead sponsor: Georgetown University; Other
Eligibility: 18 Years and older
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: McLean, Virginia

Conditions: Parkinson's Disease
Interventions: Sedation, Original Surgery; Procedure
Lead sponsor: Providence Medical Research Center; Other
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2025
U.S. locations: 1
States / cities: Spokane, Washington

Conditions: Parkinson&Amp;#39;s Disease
Interventions: Folic Acid 1 MG, Vitamin B6 25 MG, Vitamin B12; Dietary Supplement
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 40 Years to 90 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Parkinson's Disease
Interventions: VY-AADC02, Sham (Placebo) Surgery; Biological · Other
Lead sponsor: Neurocrine Biosciences; Industry
Eligibility: 40 Years to 75 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 11
States / cities: Irvine, California • Sacramento, California • San Francisco, California + 8 more

Conditions: Parkinson Disease, Orthostatic Hypotension
Interventions: Autonomic testing on and off levodopa; Drug
Lead sponsor: University of Utah; Other
Eligibility: Not listed
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Parkinson Disease
Interventions: Vibrotactile Coordinated Reset (vCR); Device
Lead sponsor: Stanford University; Other
Eligibility: 35 Years to 92 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Stanford, California

Conditions: Parkinson's Disease (PD)
Interventions: ABBV-951; Drug
Lead sponsor: AbbVie; Industry
Eligibility: 45 Years to 85 Years
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 7
States / cities: Glendale, California • Orlando, Florida • Grayslake, Illinois + 4 more

Conditions: Parkinson's Disease (PD)
Interventions: ABBV-951; Drug
Lead sponsor: AbbVie; Industry
Eligibility: 30 Years to 85 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 12
States / cities: Sun City, Arizona • Loma Linda, California • Orange, California + 9 more

Conditions: Parkinson Disease
Interventions: Spheramine (BAY86-5280), Placebo; Biological · Procedure
Lead sponsor: Bayer; Industry
Eligibility: 30 Years to 70 Years
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2012
U.S. locations: 10
States / cities: Birmingham, Alabama • Los Angeles, California • Tampa, Florida + 7 more

Conditions: Parkinson Disease
Interventions: GOCOVRI; Drug
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 50 Years to 80 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Portland, Oregon

About this Parkinson's Disease clinical trials directory page

What this page lists: U.S. ClinicalTrials.gov public records that list Parkinson's Disease as a study condition, including recruiting, not yet recruiting, and active not recruiting trials across phase 1, phase 2, and phase 3.
How to narrow results: Use the filters above to scope by intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, age, or NCT ID within Parkinson's Disease.
Where the data comes from: Records are sourced from the official ClinicalTrials.gov public API. Each result links back to the official study page, which is the source of truth for eligibility, enrollment, and contact information.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, ranking of trials by quality, or AI-generated medical summaries.

Parkinson's Disease clinical trials

How Parkinson's Disease studies are organized in the registry

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Live official records

Preventing Levodopa Induced Dyskinesia in Parkinson's Disease With HMG-CoA Reductase Inhibitors

Flexible-Dose, Adjunctive Therapy Trial in Adults With Parkinson's Disease With Motor Fluctuations (TEMPO-3)

Istradefylline Effect Protocol on Parkinson's Disease Tremor

Asleep Versus Awake Deep Brain Stimulation Surgery

Pilot Study of Open Label Homocysteine Management Therapy in Levodopa-treated Parkinson's Disease

VY-AADC02 for Parkinson's Disease With Motor Fluctuations (RESTORE-1)

Effect of Levodopa on Cardiovascular Autonomic Function in Parkinson's Disease

Vibrotactile Coordinated Reset for the Treatment of Post Surgery Refractory Parkinson's Disease Patients

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Subcutaneous Infusions of ABBV-951 in Subjects With Parkinson's Disease

A Study in Subjects With Parkinson's Disease to Evaluate the Safety and Tolerability of Titration and Continuous Subcutaneous Infusion of ABBV-951 in an Outpatient Environment

STEPS Trial - Spheramine Safety and Efficacy Study

Effect of GOCOVRI (Amantadine, Extended Release Capsules) on Gait in Parkinson's Disease

About this Parkinson's Disease clinical trials directory page