Independent directory Public ClinicalTrials.gov records United States
Healthy Volunteer Hub

Healthy volunteer clinical trials in the U.S.

This page focuses on public ClinicalTrials.gov records that explicitly say they accept healthy volunteers. It starts with recruiting studies by default, and it does not guess the visitor's location. Add a city or state only when you want location-specific results before checking the official study record.

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 15, 2026, 8:38 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials
5029
Shown on this page
12
Default status
Recruiting
The default view starts with recruiting studies because those are usually the most actionable.
Current order
Recently updated
Within the current status filter, results are ordered by the selected sort option.
ClinicalTrials.gov exposes a structured Accepts Healthy Volunteers field, not a standardized compensation amount. Healthy volunteer does not automatically mean control group, low risk, or paid. This page is U.S.-wide unless you add a city or state filter yourself. If payment, reimbursement, screening pay, or tax handling matters, confirm it on the official record or directly with the study team.

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These controls stay within studies whose public record says they accept healthy volunteers. The default view starts with Recruiting studies, and location only changes when you add a city or state.

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Showing 433–444 of 5,029 healthy volunteer trials.
Live ClinicalTrials.gov results.

Live official records

Recruiting No phase listed Observational Accepts healthy volunteers

Evaluation of Patients With Liver Disease

NCT00001971
Conditions
Hepatitis D, Hepatitis C, Hepatitis B, Liver Disease
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
2 Years to 100 Years
Enrollment
8,050 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 1992
U.S. locations
1
States / cities
Bethesda, Maryland
Recruiting No phase listed Observational Accepts healthy volunteers

Rutgers University Study of the Genetics of Blood Cancers

NCT07714044
Conditions
Blood Cancers, Blood Cancer, Leukemia, Lymphoma, Myeloma, Hematologic Cancer, Hematologic Malignancies, Hematologic Neoplasm, Hematologic Tumors
Interventions
Not listed
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 110 Years
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Piscataway, New Jersey
Conditions
Diabetes (DM)
Interventions
Exendin-9 is a 30 amino acid peptide that is an established competitive antagonist of the GLP-1 receptor. Subjects will receive exendin-9 by intravenous infusion at a rate of 600 pmol/kg/min, Dexamethasone, Dextrose 20% solution
Drug
Lead sponsor
David D'Alessio, M.D.
Other
Eligibility
18 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Depression
Interventions
Lung scan, Apremilast, 18F-PF-06445974
Radiation · Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 70 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Healthy
Interventions
Transcutaneous Auricular Vagus Nerve Stimulation, Sham Procedure (No Stimulation)
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Recruiting Not applicable Interventional Accepts healthy volunteers

A Novel Intervention for Weight Loss in Young Adults

NCT06230744
Conditions
Weight Loss
Interventions
Lifestyle, Lifestyle II
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 40 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms

NCT06484075
Conditions
Healthy Volunteers, Alcohol Use Disorder (AUD)
Interventions
Placebo, Suvorexant
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
18 Years to 75 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
End Stage Renal Disease, Renal Impairment, Obesity, Overweight
Interventions
Ribupatide
Drug
Lead sponsor
Kailera
Industry
Eligibility
18 Years to 85 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
2
States / cities
Orlando, Florida • San Antonio, Texas
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Digital STEADI Efficacy

NCT07852650
Conditions
Fall, Mild Cognitive Impairment (MCI), Aging
Interventions
Digital STEADI-1, STEADI Standard of Care, Digital STEADI-2, Attentional control
Behavioral
Lead sponsor
Friendi.fi Corporation
Industry
Eligibility
50 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Atlanta, Georgia
Recruiting No phase listed Observational Accepts healthy volunteers

Blinatumomab Consolidation in Real World

NCT07117136
Conditions
B-Cell Acute Lymphoblastic Leukaemia
Interventions
Not listed
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
5
States / cities
Jacksonville, Florida • Chicago, Illinois • Philadelphia, Pennsylvania + 1 more
Recruiting No phase listed Observational Accepts healthy volunteers

Natural History of Craniofacial Anomalies and Developmental Growth Variants

NCT02639312
Conditions
Prognathism, Retrognathism, Dentofacial Deformities
Interventions
Not listed
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
2 Years to 100 Years
Enrollment
2,400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2046
U.S. locations
1
States / cities
Bethesda, Maryland
Recruiting No phase listed Observational Accepts healthy volunteers

Ultrasound Evaluation for Improving Patient Selection in vNOTES

NCT05623514
Conditions
Surgery
Interventions
Trans-vaginal ultrasound
Diagnostic Test
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older · Female only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Houston, Texas