ClinicalTrials.gov record
Recruiting Phase 1 Interventional Accepts healthy volunteers

[18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET

ClinicalTrials.gov ID: NCT05703685

Public ClinicalTrials.gov record NCT05703685. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 29, 2026, 8:53 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Study identification

NCT ID
NCT05703685
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 1
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Enrollment
108 participants

Conditions and interventions

Conditions

Interventions

  • 18F-PF-06445974 Drug
  • Apremilast Drug
  • Lung scan Radiation

Drug · Radiation

Eligibility (public fields only)

Age range
18 Years to 70 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 21, 2023
Primary completion
Oct 2, 2028
Completion
Apr 10, 2029
Last update posted
Apr 23, 2026

2023 – 2029

United States locations

U.S. sites
1
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
National Institutes of Health Clinical Center Bethesda Maryland 20892 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05703685, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 23, 2026 · Synced Apr 29, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05703685 live on ClinicalTrials.gov.

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