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Healthy Volunteer Hub

Healthy volunteer clinical trials in the U.S.

This page focuses on public ClinicalTrials.gov records that explicitly say they accept healthy volunteers. It starts with recruiting studies by default, and it does not guess the visitor's location. Add a city or state only when you want location-specific results before checking the official study record.

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 17, 2026, 1:06 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials
5021
Shown on this page
12
Default status
Recruiting
The default view starts with recruiting studies because those are usually the most actionable.
Current order
Recently updated
Within the current status filter, results are ordered by the selected sort option.
ClinicalTrials.gov exposes a structured Accepts Healthy Volunteers field, not a standardized compensation amount. Healthy volunteer does not automatically mean control group, low risk, or paid. This page is U.S.-wide unless you add a city or state filter yourself. If payment, reimbursement, screening pay, or tax handling matters, confirm it on the official record or directly with the study team.
Read the healthy volunteer and paid studies guide

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These controls stay within studies whose public record says they accept healthy volunteers. The default view starts with Recruiting studies, and location only changes when you add a city or state.

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Showing 721–732 of 5,021 healthy volunteer trials.
Live ClinicalTrials.gov results.

Live official records

Read the guide Open in full search
Recruiting Not applicable Interventional Accepts healthy volunteers

Women Informed to Screen Depending on Measures of Risk (Wisdom Study)

NCT02620852
View directory record Official record
Conditions
Breast Cancer Screening, Breast Carcinoma in Situ, Breast Cancer
Interventions
Complete a health questionnaire, Provide a saliva sample for genetic testing, Screening advice based on a comprehensive risk assessment, Screening advice based on a basic risk assessment
Other · Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
30 Years to 74 Years · Female only
Enrollment
100,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2029
U.S. locations
11
States / cities
Birmingham, Alabama • Irvine, California • Los Angeles, California + 8 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 17, 2026, 1:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Hydration & Female Life Stages

NCT07653620
View directory record Official record
Conditions
Dehydration, Menstruation, Pre-menopause, Peri-menopausal Women, Post-menopausal Women, Hydration
Interventions
placebo beverage, electrolyte beverage
Other
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
18 Years to 60 Years · Female only
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
2
States / cities
Bradenton, Florida • Valhalla, New York
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 17, 2026, 1:06 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Clinical Decision Support to Increase Use of Medications for Opioid Use Disorder

NCT06526286
View directory record Official record
Conditions
Medication Abuse, Harm Reduction, Opioid Use Disorder, Supportive Care
Interventions
Medications for Opioid Use Disorder Pathway Clinical Decision Support (CDS)
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
12 Years to 89 Years
Enrollment
200,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 17, 2026, 1:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A SMART Evaluation of an Adaptive Web-based AUD Treatment for Service Members and Their Partners

NCT05619185
View directory record Official record
Conditions
Alcohol Abuse, Alcohol Use Disorder, Alcohol Drinking, Relations, Interpersonal, Military Family
Interventions
CRAFT Web-Based Intervention, Phone-Based CRAFT, CRAFT Workbook, Gottman Self-Guided Resources
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
744 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 17, 2026, 1:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Exploring Neurophysiological Markers of Brain Health

NCT06731452
View directory record Official record
Conditions
Healthy Lifestyle, Health-Related Behavior
Interventions
Strategic Memory Advanced Reasoning Training teaches meta-cognitive strategies for individuals to apply to their daily lives for improved performance
Behavioral
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
22 Years to 100 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 17, 2026, 1:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Study of Mental Health and Relationships

NCT06534827
View directory record Official record
Conditions
Mental Health
Interventions
Great Life Mentoring
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
9 Years to 16 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 17, 2026, 1:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Genomic Uniformed-Screening Against Rare Disease In All Newborns

NCT05990179
View directory record Official record
Conditions
Early Onset Genetic Conditions With Near Complete Penetrance
Interventions
Genome sequencing-based newborn screening
Other
Lead sponsor
Columbia University
Other
Eligibility
1 Day to 1 Month
Enrollment
100,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 17, 2026, 1:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Variability In Mixed Meal Tests: Fixed Versus Adjusted to Energy Needs Caloric Dose

NCT06223555
View directory record Official record
Conditions
Obesity, Healthy Volunteer
Interventions
Fixed Mixed Meal Test, Adjusted Mixed Meal Test
Other
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 99 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 17, 2026, 1:06 AM EDT
Recruiting Phase 3 Interventional Accepts healthy volunteers

Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial

NCT07567040
View directory record Official record
Conditions
Myopia
Interventions
Atropine Sulfate 0.05% Oph Soln, Placebo
Drug
Lead sponsor
Ohio State University
Other
Eligibility
6 Years to 11 Years
Enrollment
664 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
13
States / cities
Birmingham, Alabama • Berkeley, California • Fullerton, California + 10 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 17, 2026, 1:06 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Cyclic vs. Constant Estradiol: Regimens' Effects on Brain Health

NCT07831499
View directory record Official record
Conditions
Menopause, Healthy Adult, Brain, Postmenopausal
Interventions
Cyclic Estradiol, Continuous Estradiol
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
38 Years to 60 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 17, 2026, 1:06 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

A Recovery and Lifespan Study Using INTERCEPT Red Blood Cells Prepared Using the INTERCEPT Blood System for RBCs With AS-1

NCT07015437
View directory record Official record
Conditions
Healthy Subjects
Interventions
INTERCEPT Blood System for RBCs, Infusion of autologous radiolabeled RBCs
Device · Other
Lead sponsor
Cerus Corporation
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
2
States / cities
Cincinnati, Ohio • Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 17, 2026, 1:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Wearable Photoplethysmography for Non-invasive Hydration Assessment

NCT07520344
View directory record Official record
Conditions
Hydration Status
Interventions
Exercise
Other
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
18 Years to 45 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
2
States / cities
Frisco, Texas • Plano, Texas
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 17, 2026, 1:06 AM EDT