Home Institutions Cleveland Clinic clinical trials Institution Directory
Clinical trials at Cleveland Clinic Sites in Cleveland, OH
Institution pages show live ClinicalTrials.gov records that list this campus as a study site, whoever sponsors them. They do not rate, rank, or describe the institution.
ClinicalTrials.gov public records Last synced Oct 21, 2026, 3:31 PM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official matching trials
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Cleveland Clinic, Cleveland, OH
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Showing 277–288 of 1,321 matching trials with a site at Cleveland Clinic, Cleveland, OH.
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Live official records
Conditions Bladder Urothelial Carcinoma, Muscle Invasive Bladder Carcinoma, Stage II Bladder Cancer AJCC v8, Stage IIIA Bladder Cancer AJCC v8
Interventions Biospecimen Collection, Computed Tomography, Durvalumab, Futibatinib, Magnetic Resonance Imaging, Radical Cystectomy Procedure · Biological · Drug
Lead sponsor Yuanquan Yang Other
Eligibility 18 Years and older
Enrollment 24 participants
Healthy volunteers Healthy volunteers not accepted
Timeline 2024 – 2027
U.S. locations 3
States / cities Ann Arbor, Michigan • Cleveland, Ohio • Columbus, Ohio
Conditions Antibody-Mediated Rejection (AMR)
Interventions Mezagitamab, Placebo Drug
Lead sponsor Takeda Industry
Eligibility 18 Years to 80 Years
Enrollment 36 participants
Healthy volunteers Healthy volunteers not accepted
Timeline 2026 – 2029
U.S. locations 14
States / cities Los Angeles, California • San Francisco, California • Miami, Florida + 10 more
Conditions Mitral Valve Regurgitation
Interventions Mitral valve repair, Transcatheter edge-to-edge repair Procedure · Device
Lead sponsor Annetine Gelijns Other
Eligibility 60 Years and older
Enrollment 450 participants
Healthy volunteers Healthy volunteers not accepted
Timeline 2022 – 2034
U.S. locations 29
States / cities Los Angeles, California • San Francisco, California • Stanford, California + 19 more
Conditions Eosinophilic Oesophagitis
Interventions Dupilumab, Placebo Drug
Lead sponsor Sanofi Industry
Eligibility 18 Years and older
Enrollment 69 participants
Healthy volunteers Healthy volunteers not accepted
Timeline 2023 – 2028
U.S. locations 15
States / cities Murrieta, California • San Francisco, California • Jacksonville, Florida + 12 more
Conditions Obesity
Interventions Comprehensive weight loss, Enhanced lifestyle changes, Tirzepatide, Naltrexone-Bupropion, Phentermine-Topiramate, Semaglutide (Wegovy®) Other · Drug
Lead sponsor The Cleveland Clinic Other
Eligibility 25 Years to 65 Years
Enrollment 150 participants
Healthy volunteers Healthy volunteers not accepted
Timeline 2025 – 2028
U.S. locations 1
States / cities Cleveland, Ohio
Conditions Moderate Aortic Valve Stenosis
Interventions Medtronic Evolut PRO+ TAVR System, or Evolut FX TAVR System, and guideline-directed management and therapy (GDMT) Device
Lead sponsor Medtronic Cardiovascular Industry
Eligibility 65 Years and older
Enrollment 650 participants
Healthy volunteers Healthy volunteers not accepted
Timeline 2022 – 2034
U.S. locations 52
States / cities Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 47 more
Conditions BPH With Symptomatic Lower Urinary Tract Symptoms, BPH With Urinary Obstruction
Interventions holmium laser, pulsed thulium laser Device
Lead sponsor Smita De Other
Eligibility 18 Years and older · Male only
Enrollment 50 participants
Healthy volunteers Accepts healthy volunteers
Timeline 2025 – 2026
U.S. locations 1
States / cities Cleveland, Ohio
Conditions Uterine Prolapse
Interventions Minimally invasive supracervical hysterectomy and sacrocolpopexy (MI-SCH+SCP), Vaginal hysterectomy with uterosacral ligament suspension (TVH+USLS) Procedure
Lead sponsor University Hospitals Cleveland Medical Center Other
Eligibility 18 Years to 80 Years · Female only
Enrollment 300 participants
Healthy volunteers Healthy volunteers not accepted
Timeline 2021 – 2029
U.S. locations 7
States / cities Jacksonville, Florida • Chicago, Illinois • Durham, North Carolina + 2 more
Conditions Lymphoma
Interventions Rituximab, Methotrexate, Procarbazine, Temozolomide, Liso-cel, Fludarabine, Cyclophosphamide, Calcium folinate Drug · Biological
Lead sponsor Juno Therapeutics, Inc., a Bristol-Myers Squibb Company Industry
Eligibility 18 Years and older
Enrollment 65 participants
Healthy volunteers Healthy volunteers not accepted
Timeline 2025 – 2028
U.S. locations 14
States / cities Aurora, Colorado • Tampa, Florida • Chicago, Illinois + 11 more
Conditions Benign Prostatic Hyperplasia With Outflow Obstruction, Urinary Retention, Lower Urinary Tract Symptoms
Interventions Preoperative pelvic floor physical therapy Behavioral
Lead sponsor The Cleveland Clinic Other
Eligibility 18 Years and older · Male only
Enrollment 36 participants
Healthy volunteers Healthy volunteers not accepted
Timeline 2023 – 2026
U.S. locations 1
States / cities Cleveland, Ohio
Conditions Non-small Cell Lung Cancer (NSCLC)
Interventions Pumitamig, Durvalumab Drug
Lead sponsor Bristol-Myers Squibb Industry
Eligibility 18 Years and older
Enrollment 850 participants
Healthy volunteers Healthy volunteers not accepted
Timeline 2026 – 2034
U.S. locations 38
States / cities Daphne, Alabama • Golden, Colorado • Newark, Delaware + 32 more
Conditions Recurrent Endometrial Endometrioid Adenocarcinoma, Recurrent Malignant Uterine Corpus Neoplasm, Recurrent Ovarian Carcinoma, Recurrent Ovarian Clear Cell Adenocarcinoma, Recurrent Ovarian Endometrioid Adenocarcinoma
Interventions Computed Tomography, Magnetic Resonance Imaging, Tazemetostat Procedure · Drug
Lead sponsor National Cancer Institute (NCI) NIH
Eligibility 18 Years and older · Female only
Enrollment 62 participants
Healthy volunteers Healthy volunteers not accepted
Timeline 2019 – 2027
U.S. locations 581
States / cities Anchorage, Alaska • Goodyear, Arizona • Kingman, Arizona + 369 more About this Cleveland Clinic institution page
What this page lists ClinicalTrials.gov records that list Cleveland Clinic in Cleveland, OH as a study site, whoever sponsors them, among recruiting, not yet recruiting, and active not recruiting trials.
Site status A study's overall status can differ from this site's status. Sites marked withdrawn, terminated, or completed are not counted here. Each record shows the status listed for this site when the official record provides one.
Where the data comes from Records are sourced from the official ClinicalTrials.gov public API. Each result links back to the official study page, which is the source of truth for eligibility, enrollment, and contact information.
What this page does not do No medical advice, eligibility judgments, ranking of trials, or AI-generated medical summaries. This page does not rank or rate institutions.
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