Institution Directory

Clinical trials at Cleveland Clinic

Sites in Cleveland, OH

Institution pages show live ClinicalTrials.gov records that list this campus as a study site, whoever sponsors them. They do not rate, rank, or describe the institution.

ClinicalTrials.gov public records Last synced Nov 3, 2026, 10:22 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials

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Stored official records

Conditions: Hearing Disorder
Interventions: Electrical extracochlear stimulation; Device
Lead sponsor: Auricle Health Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Melanoma
Interventions: Fixed Dose Combination (FDC) cemiplimab+fianlimab, Placebo, cemiplimab; Drug
Lead sponsor: Regeneron Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 151 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2030
U.S. locations: 28
States / cities: La Jolla, California • Los Angeles, California • Newport Beach, California + 22 more

Conditions: Paravalvular Aortic Regurgitation
Interventions: AVP III; Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 14
States / cities: Birmingham, Alabama • Atlanta, Georgia • Boston, Massachusetts + 10 more

Conditions: Atrial Fibrillation, Bleeding, Stroke
Interventions: Left Atrial Appendage Occlusion (Amplatzer Amulet LAA Occluder), Non-Vitamin K Oral Antagonists; Device · Drug
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 2,650 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2031
U.S. locations: 79
States / cities: Birmingham, Alabama • Huntsville, Alabama • Phoenix, Arizona + 65 more

Conditions: Chronic Low Back Pain (CLBP)
Interventions: Lumbar radiofrequency ablation with conventional electrodes (LRFA-C), Lumbar radiofrequency ablation with multi-tined electrodes (LRFA-M), Simulated lumbar radiofrequency ablation; Procedure
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 3
States / cities: Atlanta, Georgia • Cleveland, Ohio • Salt Lake City, Utah

Conditions: Supratentorial Hemorrhage
Interventions: Aurora Surgiscope System; Device
Lead sponsor: Integra LifeSciences Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2029
U.S. locations: 20
States / cities: Burbank, California • Miami, Florida • Tampa, Florida + 17 more

Conditions: Peripheral Arterial Disease
Interventions: Not listed
Lead sponsor: Baylor Research Institute; Other
Eligibility: Not listed
Enrollment: 14,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2033
U.S. locations: 24
States / cities: Little Rock, Arkansas • Denver, Colorado • Atlanta, Georgia + 17 more

Conditions: Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8
Interventions: Degarelix, Enzalutamide, Goserelin Acetate, Leuprolide Acetate, Placebo, Quality-of-Life Assessment, Questionnaire Administration, Rucaparib camsylate; Drug · Other
Lead sponsor: Alliance for Clinical Trials in Oncology; Other
Eligibility: 18 Years and older · Male only
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 414
States / cities: Anchorage, Alaska • Phoenix, Arizona • Hot Springs, Arkansas + 298 more

Conditions: Heart Failure
Interventions: Quadripolar LV Lead; Device
Lead sponsor: Medtronic; Industry
Eligibility: Not listed
Enrollment: 1,092 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2028
U.S. locations: 72
States / cities: Anchorage, Alaska • Chandler, Arizona • Jonesboro, Arkansas + 62 more

Conditions: Deletion and Duplication of Mitochondrial DNA, Disorder of Mitochondrial Respiratory Chain Complexes, Mitochondrial Diseases, Mitochondrial Disorders, Mitochondrial Genetic Disorders
Interventions: Not listed
Lead sponsor: Columbia University; Other
Eligibility: Not listed
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2026
U.S. locations: 16
States / cities: San Diego, California • Stanford, California • Aurora, Colorado + 12 more

Conditions: FSGS
Interventions: DMX-200, Placebo; Drug
Lead sponsor: Dimerix Bioscience Pty Ltd; Industry
Eligibility: 12 Years to 80 Years
Enrollment: 286 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2029
U.S. locations: 54
States / cities: Birmingham, Alabama • Phoenix, Arizona • Loma Linda, California + 44 more

Conditions: BCLC Stage A Hepatocellular Carcinoma, BCLC Stage B Hepatocellular Carcinoma, BCLC Stage C Hepatocellular Carcinoma, Unresectable Hepatocellular Carcinoma
Interventions: Resin microspheres containing yttrium-90 (Y-90); Device
Lead sponsor: Sirtex Medical; Industry
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 22
States / cities: Los Angeles, California • Orange, California • Miami, Florida + 16 more

About this Cleveland Clinic institution page

What this page lists: ClinicalTrials.gov records that list Cleveland Clinic in Cleveland, OH as a study site, whoever sponsors them, among recruiting, not yet recruiting, and active not recruiting trials.
Site status: A study's overall status can differ from this site's status. Sites marked withdrawn, terminated, or completed are not counted here. Each record shows the status listed for this site when the official record provides one.
Where the data comes from: Records are sourced from the official ClinicalTrials.gov public API. Each result links back to the official study page, which is the source of truth for eligibility, enrollment, and contact information.
What this page does not do: No medical advice, eligibility judgments, ranking of trials, or AI-generated medical summaries. This page does not rank or rate institutions.

Clinical trials at Cleveland Clinic

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Stored official records

Evaluation of Cochlear (Promontory) Stimulation During Awake Ear Surgery (TONES Study)

A Trial to Learn if Fianlimab and Cemiplimab Are Safe and Work Better Than Anti-PD1 Alone in Adult Participants With Resectable Stage 3 or 4 Melanoma

PARADIGM: Amplatzer Valvular Plug for PVL Closure

Amplatzer Amulet LAAO vs. NOAC

A Superiority Trial of Radiofrequency Ablation for Low Back Pain

The MIRROR Registry: Minimally Invasive IntRaceRebral HemORrhage Evacuation

Multi-Center Registry for Peripheral Arterial Disease Interventions and Outcomes

A Clinical Study Evaluating The Benefit of Adding Rucaparib to Enzalutamide for Men With Metastatic Prostate Cancer That Has Become Resistant To Testosterone-Deprivation Therapy

Personalized Therapy Study - Attain Stability Quad Post-Approval Study

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

A Study of the Efficacy and Safety of DMX-200 in Patients With FSGS Who Are Receiving an ARB

Selective Internal Radiation Therapy (SIRT) Using SIR-Spheres® Y-90 Resin Microspheres on DoR & ORR in Unresectable Hepatocellular Carcinoma Patients

About this Cleveland Clinic institution page