Institution Directory

Clinical trials at Massachusetts General Hospital

Sites in Boston, MA

Institution pages show live ClinicalTrials.gov records that list this campus as a study site, whoever sponsors them. They do not rate, rank, or describe the institution.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 3:21 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official matching trials

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Conditions: Ascending Aorta Aneurysm, Ascending Aortic Aneurysm Enlargement
Interventions: Thoracic Aortic Surgery; Procedure
Lead sponsor: Ottawa Heart Institute Research Corporation; Other
Eligibility: 18 Years to 79 Years
Enrollment: 610 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2035
U.S. locations: 16
States / cities: San Francisco, California • Iowa City, Iowa • Boston, Massachusetts + 12 more

Conditions: Pyruvate Kinase Deficiency
Interventions: Not listed
Lead sponsor: Agios Pharmaceuticals, Inc.; Industry
Eligibility: Not listed
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2027
U.S. locations: 15
States / cities: Phoenix, Arizona • Little Rock, Arkansas • Orange, California + 10 more

Conditions: Bundle Care, Critical Illness, Delirium, Implementation Science, Sleep Deprivation, Sleep-Wake Disorders
Interventions: Clustering patient-care interactions, Daytime light exposure, Encourage out-of-bed activity, Medication management to support nighttime sleep, Nighttime noise & light reduction, Non-pharmacologic sleep aids; Behavioral · Other
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 62,500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 7
States / cities: La Jolla, California • San Francisco, California • Orlando, Florida + 4 more

Conditions: Gut Microbiome, Gut Microbiota, PARKINSON DISEASE (Disorder), Parkinson Disease (PD), Prodromal Parkinsons Disease
Interventions: Not listed
Lead sponsor: Duke University; Other
Eligibility: 21 Years to 80 Years
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2028
U.S. locations: 7
States / cities: Stanford, California • Chicago, Illinois • Boston, Massachusetts + 3 more

Conditions: Multiple Myeloma
Interventions: JNJ-79635322; Drug
Lead sponsor: Janssen Research & Development, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 168 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 30
States / cities: Birmingham, Alabama • Gilbert, Arizona • Duarte, California + 24 more

Conditions: Immunosuppresion, Immunosuppression After Kidney Transplantation, Kidney Failure, Transplant Recipient (Kidney), Transplant Tolerance
Interventions: Combined Kidney/Bone Marrow Transplant, Conditioning Regimen (Rituxan, Siplizumab (or ATGAM), Cyclophosphamide, Tegoprubart), Donation of Kidney / Bone Marrow; Procedure · Drug
Lead sponsor: Tatsuo Kawai, MD, PhD; Other
Eligibility: 18 Years to 65 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Prostate Cancer (Adenocarcinoma), mCRPC (Metastatic Castration-resistant Prostate Cancer)
Interventions: ACE-232 tablets; Drug
Lead sponsor: Acerand Therapeutics (Hong Kong) Limited; Industry
Eligibility: 18 Years and older · Male only
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 8
States / cities: La Jolla, California • Tampa, Florida • Baltimore, Maryland + 5 more

Conditions: Angioimmunoblastic T-cell Lymphoma, Follicular T-Cell Lymphoma, Lymphoma, T-Cell, Lymphoma, T-Cell, Peripheral, Nodal Peripheral T-Cell Lymphoma With TFH Phenotype, Peripheral T-Cell Lymphoma, Not Otherwise Specified, Systemic Anaplastic Large Cell Lymphoma
Interventions: Belinostat, Pralatrexate, Soquelitinib; Drug
Lead sponsor: Corvus Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 24
States / cities: Duarte, California • Irvine, California • San Francisco, California + 19 more

Conditions: Carcinoma, Hepatocellular, Hepatitis B, Liver Cancer, Liver Cirrhosis
Interventions: GALAD, Liver Ultrasound with or without AFP; Diagnostic Test
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 85 Years
Enrollment: 5,500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2034
U.S. locations: 19
States / cities: Los Angeles, California • Redwood City, California • Roseville, California + 14 more

Conditions: Leukemia, Myeloid, Acute
Interventions: Azacitidine (AZA), Bleximenib, Cytarabine, Daunorubicin or Idarubicin, Venetoclax (VEN); Drug
Lead sponsor: Janssen Research & Development, LLC; Industry
Eligibility: 12 Years and older
Enrollment: 196 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 7
States / cities: Birmingham, Alabama • Duarte, California • Boston, Massachusetts + 4 more

Conditions: Multiple Myeloma
Interventions: Cilta-cel; Drug
Lead sponsor: Janssen Research & Development, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 295 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2041
U.S. locations: 28
States / cities: Phoenix, Arizona • Duarte, California • San Francisco, California + 21 more

Conditions: Wilson Disease
Interventions: Standard of Care (SOC), UX701; Drug · Genetic
Lead sponsor: Ultragenyx Pharmaceutical Inc; Industry
Eligibility: 18 Years and older
Enrollment: 82 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2034
U.S. locations: 12
States / cities: Los Angeles, California • Redwood City, California • Sacramento, California + 9 more

About this Massachusetts General Hospital institution page

What this page lists: ClinicalTrials.gov records that list Massachusetts General Hospital in Boston, MA as a study site, whoever sponsors them, among recruiting, not yet recruiting, and active not recruiting trials.
Site status: A study's overall status can differ from this site's status. Sites marked withdrawn, terminated, or completed are not counted here. Each record shows the status listed for this site when the official record provides one.
Where the data comes from: Records are sourced from the official ClinicalTrials.gov public API. Each result links back to the official study page, which is the source of truth for eligibility, enrollment, and contact information.
What this page does not do: No medical advice, eligibility judgments, ranking of trials, or AI-generated medical summaries. This page does not rank or rate institutions.

Clinical trials at Massachusetts General Hospital

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Stored official records

Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance

Pyruvate Kinase Deficiency Global Longitudinal Registry

Sleep Harmonization Via Bundled Team-Based Interventions in the ICU

GBPDC: Gut-Brain in PD Consortium Master Protocol

A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma

Tolerance Through Mixed Chimerism (Sip-Tego)

Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer

Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma

National Liver Cancer Screening Trial

A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapies

A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel

A Phase 1/2/3 Study of UX701 Gene Therapy in Adults With Wilson Disease

About this Massachusetts General Hospital institution page