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ClinicalTrials.gov public records Last synced Oct 19, 2026, 12:12 AM EDT

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Showing 769–792 of 1,923 matching trials from the local directory fallback.

Filters: Durham, North Carolina Clear all

Conditions: Previously Treated Non-Small Cell Lung Cancer
Interventions: Screening Platform; Drug
Lead sponsor: SWOG Cancer Research Network; Network
Eligibility: 18 Years and older
Enrollment: 10,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2029
U.S. locations: 1229
States / cities: Birmingham, Alabama • Daphne, Alabama • Fairhope, Alabama + 807 more

Conditions: Respiratory Viral Infection
Interventions: Ozone; Drug
Lead sponsor: Robert Tighe, MD; Other
Eligibility: 18 Years to 55 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Adolescent and Young Adult Cancer, Cancer Survivorship, Family Planning
Interventions: Nurse Navigator-Delivered Family Building Decision Support, Survivorship Education; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 39 Years · Female only
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Cancer, Early Menopause, Premature Menopause, Surgical Menopause
Interventions: Education Control, Nurse Navigator Intervention; Other · Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 44 Years · Female only
Enrollment: 117 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Multiple Myeloma
Interventions: Linvoseltamab; Drug
Lead sponsor: Regeneron Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 149 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2035
U.S. locations: 13
States / cities: Los Angeles, California • Orange, California • Denver, Colorado + 9 more

Conditions: Alport Syndrome, Focal Segmental Glomerulosclerosis, IgA Vasculitis, Immunoglobulin A Nephropathy, Minimal Change Disease
Interventions: Sparsentan; Drug
Lead sponsor: Travere Therapeutics, Inc.; Industry
Eligibility: 1 Year to 17 Years
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 23
States / cities: Los Angeles, California • Wilmington, Delaware • Miami, Florida + 17 more

Conditions: Acute Respiratory Failure
Interventions: Colorimetric carbon dioxide (CO2) detection, Waveform capnography; Diagnostic Test
Lead sponsor: Brian Driver; Other
Eligibility: 18 Years and older
Enrollment: 2,092 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 9
States / cities: Chicago, Illinois • Burlington, Massachusetts • Minneapolis, Minnesota + 6 more

Conditions: Atrial Fibrillation, Intracerebral Hemorrhage
Interventions: Apixaban, Aspirin; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 700 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2027
U.S. locations: 186
States / cities: Birmingham, Alabama • Mobile, Alabama • Chandler, Arizona + 141 more

Conditions: Aging, Sickle Cell Disease
Interventions: SickleFit Exercise plus Nutrition; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 35 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Chronic Insomnia
Interventions: Implementation Strategy: Foundational Arm, Implementation Strategy: REACH arm; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 60 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Knee Osteoarthritis
Interventions: Implementation Strategy: Foundational Arm, Implementation Strategy: REACH Arm; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: Not listed
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: FSHD
Interventions: Not listed
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: Not listed
Enrollment: 450 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2028
U.S. locations: 16
States / cities: Los Angeles, California • Stanford, California • Aurora, Colorado + 13 more

Conditions: Cancer, Distress, Psychological, Young Adult Cancer, Youth Cancer
Interventions: Mindset Moments; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 19 Years to 25 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Abdominal Trauma
Interventions: Nutrition Supplement; Dietary Supplement
Lead sponsor: Duke University; Other
Eligibility: 15 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: AL Amyloidosis
Interventions: Autologous Hematopoietic Stem Cell Transplantation, Biopsy, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Bortezomib, Computed Tomography, Cyclophosphamide, Daratumumab and Hyaluronidase-fihj, Dexamethasone, Echocardiography, Magnetic Resonance Imaging, Melphalan, Positron Emission Tomography, Stem Cell Isolation, Survey Administration; Procedure · Drug · Other
Lead sponsor: SWOG Cancer Research Network; Network
Eligibility: 18 Years and older
Enrollment: 338 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2030
U.S. locations: 117
States / cities: Goodyear, Arizona • Tucson, Arizona • Duarte, California + 93 more

Conditions: Spinal Deformity, Spinal Injuries
Interventions: Placebo, Tranexamic Acid; Drug
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 252 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2027
U.S. locations: 4
States / cities: San Francisco, California • Louisville, Kentucky • New York, New York + 1 more

Conditions: ADHD, ADHD - Attention Deficit Disorder With Hyperactivity
Interventions: Not listed
Lead sponsor: Duke University; Other
Eligibility: 6 Years to 9 Years
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Heart Failure
Interventions: Sham-control procedure, Splanchnic nerve block; Other · Device
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Fragility Fracture, Osteoporosis, Osteoporotic Fractures
Interventions: Augmented-Fracture Liaison Service Arm, Enhanced Usual Care Arm; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 50 Years and older
Enrollment: 2,634 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 23
States / cities: Birmingham, Alabama • Scottsdale, Arizona • North Little Rock, Arkansas + 19 more

Conditions: Chronic Pain, Sickle Cell Disease
Interventions: Quantitative sensory testing; Other
Lead sponsor: Duke University; Other
Eligibility: 15 Years to 40 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Malignant Solid Neoplasm
Interventions: Biospecimen Collection, Questionnaire Administration; Procedure · Other
Lead sponsor: SWOG Cancer Research Network; Network
Eligibility: 18 Years and older
Enrollment: 2,062 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2028
U.S. locations: 843
States / cities: Anchorage, Alaska • Fairbanks, Alaska • Kingman, Arizona + 550 more

Conditions: GLYCOGEN STORAGE DISEASE IXa1, GLYCOGEN STORAGE DISEASE IXa2, GSD 6, GSD 9 (All Subtypes), Glycogen Storage Disease IXB, Glycogen Storage Disease IXC, Glycogen Storage Disease VI
Interventions: No intervention; Other
Lead sponsor: Duke University; Other
Eligibility: 0 Years to 90 Years
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2030
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Surgery
Interventions: COMPAS Participants; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years to 90 Years
Enrollment: 10,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: APBD, Adult Polyglucosan Body Disease, GSD IV, GSD4, Glycogen Storage Disease Type IV
Interventions: No intervention; Other
Lead sponsor: Duke University; Other
Eligibility: 0 Years to 90 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2035
U.S. locations: 1
States / cities: Durham, North Carolina

Search by objective public record fields.

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

Macrophage Regulation of Ozone-Induced Lung Inflammation

Family Building Decision Support for Female Adolescent and Young Adult Cancer Survivors

Improving Outcomes in Early Menopause After Cancer

A Window of Opportunity Trial to Learn if Linvoseltamab is Safe and Well Tolerated, and How Well it Works in Adult Participants With Recently Diagnosed Multiple Myeloma Who Have Not Already Received Treatment

Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases

Waveform Capnography Compared to Colorimetric Carbon Dioxide Detection During Tracheal Intubation of Critically Ill Adults

Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

SickleFit Exercise and Nutrition Study

Implementing Cognitive Behavioral Therapy for Insomnia (SWELL): Function QUERI 3.0

Implementing a Group Physical Therapy Program for Veterans (GroupPT): Function QUERI 3.0

Motor Outcomes to Validate Evaluations in FSHD (MOVE FSHD)

Pilot Study of Mindset Moments Among Adolescent and Young Adult Cancer Survivors

Personalized Nutrition to Improve Recovery in Trauma

Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

Tranexamic Acid to Reduce Blood Loss in Spine Surgery

Advancing Identification of Circadian Delay in ADHD Youth: Associations With Clinical Heterogeneity and Cognition

Splanchnic X: Splanchnic Nerve Block in Heart Failure With Reduced Ejection Fraction

RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE

Predictors of Pain in Sickle Cell Disease

Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

GSD VI and GSD IX Natural History

Collecting Outcomes and Managing Pain After Surgery

GBE Deficiency (GSD IV and APBD) Natural History Study