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ClinicalTrials.gov public records Last synced Oct 21, 2026, 2:08 AM EDT

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Showing 97–120 of 216 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: ACT Clear all
Completed Not applicable Interventional

Guided Eight-week Online Acceptance and Commitment Therapy for Distressed Family Caregivers of People With Dementia

NCT04847986
View directory record Official record
Conditions
Psychological Distress
Interventions
acceptance and commitment therapy (ACT), Control group
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 28, 2022 · Synced Oct 21, 2026, 2:08 AM EDT
Completed Not applicable Interventional

Digital Intervention for Adults With Misophonia

NCT07220941
View directory record Official record
Conditions
Misophonia
Interventions
Acceptance and commitment therapy
Behavioral
Lead sponsor
Utah State University
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Logan, Utah
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 21, 2026, 2:08 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

ACT Group for Family Caregivers of Stroke Survivors

NCT07528261
View directory record Official record
Conditions
Caregiver Stress, Caregiver Stress Syndrome, Caregiver Burnout, Caregiver Distress, Caregiver Exhaustion, Caregiver Health Related QOL, Caregiver Burden for Those Who Care for Adults With Impaired Functional Status, Caregiver Quality of Life, Caregiver Burden, Caregiver Mental Health, Caregiver Resilience and Stress, Caregiver Sense of Control Over Life, Caregiver Awareness, Caregiver Stress in Chronic Mental Illness
Interventions
Group-based ACT Intervention
Behavioral
Lead sponsor
The Wright Institute
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Alameda, California
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 21, 2026, 2:08 AM EDT
Terminated Not applicable Interventional

ACT for HIV-Positive Men

NCT06625437
View directory record Official record
Conditions
Stress, Anxiety, Mental Disorder, Distress-based Psychopathology
Interventions
Acceptance and commitment therapy
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Male only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 21, 2026, 2:08 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Evaluate the Pharmacokinetics of a Single Dose of Tafenoquine Co-administered With Either Artemether + Lumefantrine or Dihydroartemisinin + Piperaquine Tetraphosphate

NCT02184637
View directory record Official record
Conditions
Malaria, Vivax
Interventions
Tafenoquine, Dihydroartemisinin + Piperaquine tetraphosphate, Artemether + Lumefantrine
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 13, 2017 · Synced Oct 21, 2026, 2:08 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Blood and Stool Sample Collection in Subjects Participating in Colorectal Cancer Screening: Act Bold

NCT03821948
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Not listed
Lead sponsor
Exact Sciences Corporation
Industry
Eligibility
40 Years and older
Enrollment
5,131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
40
States / cities
Tempe, Arizona • Chula Vista, California • Huntington Beach, California + 36 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2020 · Synced Oct 21, 2026, 2:08 AM EDT
Completed No phase listed Observational

Acceptance and Commitment Therapy (ACT) - Based Treatment Development for Cancer Patients Treated for Pain

NCT03910296
View directory record Official record
Conditions
Cancer
Interventions
Acceptance & Commitment Therapy
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 3, 2022 · Synced Oct 21, 2026, 2:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparing Acceptance and Commitment Therapy (ACT) and Cognitive Therapy (CT) for Test Anxiety

NCT00850226
View directory record Official record
Conditions
Anxiety
Interventions
CT, ACT
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 2, 2010 · Synced Oct 21, 2026, 2:08 AM EDT
Completed Phase 1Phase 2 Interventional

Analyzing the Composition of Tears to Identify Cancer

NCT00574678
View directory record Official record
Conditions
Breast Cancer, Ovarian Cancer, Colon Cancer, Benign Disease
Interventions
Tear collection
Other
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2016
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Aug 5, 2021 · Synced Oct 21, 2026, 2:08 AM EDT
Terminated Not applicable Interventional Results available

Carotid Angioplasty and Stenting Versus Endarterectomy in Asymptomatic Subjects Who Are at Standard Risk for Carotid Endarterectomy With Significant Extracranial Carotid Stenotic Disease (ACT I)

NCT00106938
View directory record Official record
Conditions
Carotid Artery Disease, Carotid Stenosis, Stroke, Atherosclerosis
Interventions
Carotid artery stenting with filter (interventional), Carotid artery endarterectomy (surgical)
Device · Procedure
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 79 Years
Enrollment
1,663 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2013
U.S. locations
62
States / cities
Phoenix, Arizona • Mountain View, California • Newport Beach, California + 52 more
Source: ClinicalTrials.gov public record
Updated Jul 19, 2017 · Synced Oct 21, 2026, 2:08 AM EDT
Completed Not applicable Interventional

Enhanced Kidney Follow-up for AKI Survivors in Care Transitions

NCT04505891
View directory record Official record
Conditions
Acute Kidney Injury
Interventions
Education, Education and follow-up
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 5, 2022 · Synced Oct 21, 2026, 2:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Acceptance Based PrEP Intervention to Engage Young Black MSM in the South

NCT05087680
View directory record Official record
Conditions
HIV Prevention
Interventions
ACTPrEP, Enhanced Standard of Care
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 34 Years · Male only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 21, 2026, 2:08 AM EDT
Completed No phase listed Observational

To Determine the Validity of the ACT in an Adolescent Population With Persistent Asthma

NCT02662413
View directory record Official record
Conditions
Asthma
Interventions
Validation of Asthma Control Questionnaire
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
12 Years to 18 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 23, 2018 · Synced Oct 21, 2026, 2:08 AM EDT
Completed Phase 3 Interventional Results available

Clinical Study to Assess the Long-term Safety and Tolerability of ACT 064992 in Patients With Symptomatic Pulmonary Arterial Hypertension

NCT00667823
View directory record Official record
Conditions
Pulmonary Arterial Hypertension
Interventions
Macitentan
Drug
Lead sponsor
Actelion
Industry
Eligibility
12 Years and older
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2020
U.S. locations
39
States / cities
Birmingham, Alabama • Phoenix, Arizona • La Jolla, California + 32 more
Source: ClinicalTrials.gov public record
Updated Mar 30, 2025 · Synced Oct 21, 2026, 2:08 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

An Aging Healthy Intervention for Older Adults Delivered by Community Health Workers in Senior Centers: A Clinical Trial

NCT07428174
View directory record Official record
Conditions
Healthy Aging
Interventions
aCT CHW intervention
Behavioral
Lead sponsor
George Mason University
Other
Eligibility
60 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Hazard, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Oct 21, 2026, 2:08 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Cilostazol and Its Effects on Resumption of Meiosis in the Human Ovary

NCT01915069
View directory record Official record
Conditions
Contraception
Interventions
Cilostazol
Drug
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 33 Years · Female only
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 12, 2015 · Synced Oct 21, 2026, 2:08 AM EDT
Completed Phase 3 Interventional Results available

Trial in Locally Advanced and Metastatic Adrenocortical Carcinoma Treatment (FIRM-ACT)

NCT00094497
View directory record Official record
Conditions
Carcinoma, Adrenal Cortical
Interventions
Etoposide, Doxorubicin, Cisplatin, Streptozotocin, Mitotane
Drug
Lead sponsor
Collaborative Group for Adrenocortical Carcinoma Treatment
Other
Eligibility
18 Years and older
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
2
States / cities
Bethesda, Maryland • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 21, 2016 · Synced Oct 21, 2026, 2:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ACT for Healthy Living: a Brief Acceptance and Commitment Therapy Intervention for Women With Obesity

NCT05885438
View directory record Official record
Conditions
Obesity
Interventions
ACT workshop
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
40 Years to 70 Years · Female only
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 12, 2025 · Synced Oct 21, 2026, 2:08 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

The Active by Choice Today (ACT) Trial to Increase Physical Activity

NCT01028144
View directory record Official record
Conditions
Exercise, Physical Activity, Obesity
Interventions
Physical Activity Program, General Health Program
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
10 Years to 13 Years
Enrollment
1,422 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 19, 2023 · Synced Oct 21, 2026, 2:08 AM EDT
Withdrawn No phase listed Observational

Oral Contraceptives and Asthma Control

NCT00662051
View directory record Official record
Conditions
Asthma, Regulatory T Cell Function
Interventions
Not listed
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 9, 2013 · Synced Oct 21, 2026, 2:08 AM EDT
Recruiting Not applicable Interventional

Achieving Chronic Care equiTy by leVeraging the Telehealth Ecosystem

NCT06598436
View directory record Official record
Conditions
Diabetes
Interventions
Digital Health Coaching (Patient-Level Intervention), Practice Facilitation (Clinic-Level Intervention)
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Oct 21, 2026, 2:08 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

ACT NOW Longitudinal Study: Outcomes of Babies With Opioid Exposure Study

NCT04149509
View directory record Official record
Conditions
Neonatal Opioid Withdrawal Syndrome
Interventions
Not listed
Lead sponsor
Advancing Clinical Trials in Neonatal Opioid Withdrawal (ACT NOW) Program
Network
Eligibility
Up to 1 Month
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
6
States / cities
Birmingham, Alabama • Washington D.C., District of Columbia • Durham, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Oct 21, 2026, 2:08 AM EDT
Completed Not applicable Interventional

ACT for High-risk Pregnancy

NCT04193514
View directory record Official record
Conditions
Acceptance and Commitment Therapy
Interventions
Acceptance and Commitment Therapy
Other
Lead sponsor
Southern Methodist University
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 17, 2022 · Synced Oct 21, 2026, 2:08 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Optimizing an Extended Care Intervention to Promote Weight Loss Maintenance

NCT06785064
View directory record Official record
Conditions
Obesity Prevention, Weight Change, Weight Loss, Weight Loss Maintenance
Interventions
Reduced Food Variety (RFV), Home-based Resistance Training (HBRT), Buddy Training and Support (BTS), Acceptance and Commitment (ACT) Workshops
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
544 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 21, 2026, 2:08 AM EDT