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Showing 169–192 of 298 matching trials from the live ClinicalTrials.gov search.
Completed Phase 4 Interventional Results available

The Home INR Study

NCT00032591
Conditions
Atrial Fibrillation
Interventions
Weekly patient self-testing of prothrombin time, High quality anticoagulation management (HQACM) with conventional monthly testing
Procedure · Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
2,922 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
28
States / cities
Birmingham, Alabama • Fresno, California • Loma Linda, California + 25 more
Conditions
Age Related Macular Degeneration
Interventions
adaptive optics AO-OCT/AF instrument
Diagnostic Test
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
60 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Conditions
Atrial Fibrillation (AF), Atrial Flutter
Interventions
Cardiac computed tomography angiography, Standard of care management
Diagnostic Test · Other
Lead sponsor
Ottawa Heart Institute Research Corporation
Other
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Hershey, Pennsylvania
Conditions
Atrial Fibrillation
Interventions
AF at Home
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
3
States / cities
Chapel Hill, North Carolina • Durham, North Carolina • Winston-Salem, North Carolina
Completed Not applicable Interventional Results available

SDM for Stroke Prevention in Atrial Fibrillation

NCT02905032
Conditions
Atrial Fibrillation
Interventions
Decision Aid
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
1,186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
5
States / cities
Birmingham, Alabama • Minneapolis, Minnesota • Rochester, Minnesota + 2 more
Conditions
Atrial Fibrillation
Interventions
High intensity interval training, Moderate intensity continuous training, No Exercise
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Atrial Fibrillation
Interventions
Electronic Health Record Best Practice Advisory
Other
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
608 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Cincinnati, Ohio
Completed Phase 3 Interventional Results available

Tailored Treatment of Permanent Atrial Fibrillation

NCT00514735
Conditions
Atrial Fibrillation
Interventions
Medtronic Cardiac Ablation System, Class I or III Antiarrhythmic Medications
Procedure · Drug
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years to 70 Years
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
23
States / cities
Scottsdale, Arizona • Los Angeles, California • Jacksonville, Florida + 18 more
Conditions
Acute Injury of Anterior Cruciate Ligament
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
13 Years to 70 Years
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
San Francisco, California
Conditions
Atrial Fibrillation
Interventions
64 pole basket catheter
Procedure
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
21 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Richmond, Virginia
Completed No phase listed Observational

Ten-year Outcomes After AF Ablation

NCT01867099
Conditions
Atrial Fibrillation
Interventions
Not listed
Lead sponsor
Valley Health System
Other
Eligibility
18 Years to 85 Years
Enrollment
445 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2012
U.S. locations
1
States / cities
Ridgewood, New Jersey
Conditions
Stroke, Atrial Fibrillation
Interventions
Non-vitamin K oral anticoagulant (NOAC)
Drug
Lead sponsor
Population Health Research Institute
Other
Eligibility
55 Years and older
Enrollment
2,270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
2
States / cities
Los Angeles, California • Houston, Texas
Conditions
Atrial Fibrillation (AF), Persistant Atrial Fibrillation
Interventions
FARAPOINT Pulsed Field Ablation System, OptiMap System (non-ablative), FARAPULSE Pulsed Field Ablation (PFA) System and Opal HDx Mapping System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
699 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
11
States / cities
Jonesboro, Arkansas • Santa Monica, California • Athens, Georgia + 8 more
Conditions
Atrial Fibrillation
Interventions
rate control via CRT-D and AVN ablation, rhythm control via pharmacologic, electrical or ablative therapies
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Terminated Not applicable Interventional Results available

Deviating the Esophagus in Atrial Fibrillation Ablation

NCT01546168
Conditions
Esophageal Deviation, Atrial Fibrillation, Ablation
Interventions
esophageal deviation with IDE device
Device
Lead sponsor
Vivek Reddy
Other
Eligibility
18 Years to 80 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
4
States / cities
Orlando, Florida • Boston, Massachusetts • New York, New York + 1 more
Conditions
Atrial Fibrillation
Interventions
Pulsed Field Ablation
Device
Lead sponsor
Heart Rhythm Clinical and Research Solutions, LLC
Other
Eligibility
18 Years and older
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
36
States / cities
Birmingham, Alabama • Jonesboro, Arkansas • Los Angeles, California + 32 more
Recruiting Not applicable Interventional

Medtronic Terminate AF Study

NCT03546374
Conditions
Persistent Atrial Fibrillation, Longstanding Persistent Atrial Fibrillation
Interventions
Surgical Ablation, Cardioblate and Cryoflex hand held devices
Procedure · Device
Lead sponsor
Medtronic Cardiac Surgery
Industry
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
15
States / cities
Palo Alto, California • St. Helena, California • Hartford, Connecticut + 11 more
Conditions
Long-standing Persistent AF
Interventions
Farawave PFA catheter
Device
Lead sponsor
Vivek Reddy
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
New York, New York
Conditions
Atrial Fibrillation (AF)
Interventions
Bachmann's Bundle Pacing, Right Atrial Appendage Pacing
Device
Lead sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Other
Eligibility
18 Years and older
Enrollment
334 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Persistent Atrial Fibrillation
Interventions
AtriCure EPi-Sense-AF Guided Coagulation System with VisiTrax, Endocardial RF Catheter ablation using Open Irrigated-tip RF Abaltion Catheter with unidirectional or bidirectional steering
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
25
States / cities
Birmingham, Alabama • Huntsville, Alabama • Denver, Colorado + 22 more
Conditions
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation, Ventricular Arrhythmia
Interventions
Catheter ablation
Device
Lead sponsor
Heart Rhythm Clinical and Research Solutions, LLC
Other
Eligibility
18 Years and older
Enrollment
20,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
71
States / cities
Birmingham, Alabama • Mobile, Alabama • Chandler, Arizona + 64 more
Conditions
Arrhythmias, Cardiac, Atrial Fibrillation
Interventions
Intravenous Sotalol Administered as a Loading Dose to Initiate Oral Sotalol Therapy in Adult Patients with Atrial Fibrillation
Drug
Lead sponsor
Kansas City Heart Rhythm Research Foundation
Other
Eligibility
18 Years to 85 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Overland Park, Kansas
Completed No phase listed Observational Accepts healthy volunteers

WHOOP ECG Software Performance Assessment Study

NCT06622265
Conditions
Atrial Fibrillation (AF)
Interventions
Electrocardiogram recording
Device
Lead sponsor
Whoop Inc.
Industry
Eligibility
22 Years and older
Enrollment
540 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
7
States / cities
Phoenix, Arizona • Covina, California • Northridge, California + 4 more
Conditions
Osteoarthritis of the Knee
Interventions
Amniotic Fluid 4.0ml dose, Amniotic Fluid 2.0ml dose, Placebo Control
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
30 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
2
States / cities
Birmingham, Alabama • Des Plaines, Illinois