- Conditions
- Acute Decompensated Heart Failure
- Interventions
- Cardiac Perfusion and Metabolism with [11C] Acetate PET/CT
- Drug
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
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Showing 25–48
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- Conditions
- Cardiorenal Syndrome, Acute Decompensated Heart Failure
- Interventions
- Not listed
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2013
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Acute Decompensated Heart Failure
- Interventions
- SGLT2i, No SGLT2i
- Drug · Other
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Acute Decompensated Heart Failure
- Interventions
- loop diuretic, tolvaptan, ultrafiltration
- Drug · Procedure
- Lead sponsor
- The Christ Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- Heart Failure, Heart Failure - NYHA II - IV, Heart Failure Acute, Acute Heart Failure (AHF)
- Interventions
- Furosemide intravenous solution
- Drug
- Lead sponsor
- Lakeland Regional Health Systems, Inc.
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 600 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Lakeland, Florida
- Conditions
- Dyspnea, Acute Decompensated Heart Failure
- Interventions
- Recording Doppler ultrasound signals noninvasively
- Device
- Lead sponsor
- Echosense Ltd.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 600 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2018
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Heart Failure, Heart Failure With Reduced Ejection Fraction, Heart Failure Acute, Cardiovascular Diseases
- Interventions
- Metolazone Oral Tablet, Chlorothiazide Injection
- Drug
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- ADHF
- Interventions
- Lung Doppler Signals
- Device
- Lead sponsor
- Echosense Ltd.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 130 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 3
- States / cities
- Detroit, Michigan • Dallas, Texas • Houston, Texas
- Conditions
- Acute Heart Failure
- Interventions
- Not listed
- Lead sponsor
- Vanderbilt University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 835 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2015
- U.S. locations
- 2
- States / cities
- Cincinnati, Ohio • Nashville, Tennessee
- Conditions
- Acute Decompensated Heart Failure, Sleep Disordered Breathing
- Interventions
- MV ASV, Optimized Medical Treatment
- Device · Drug
- Lead sponsor
- ResMed
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 126 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 14
- States / cities
- Huntsville, Alabama • Los Angeles, California • Denver, Colorado + 11 more
- Conditions
- Heart Failure
- Interventions
- Anakinra (high dose), Anakinra (standard dose), Placebo
- Drug
- Lead sponsor
- Virginia Commonwealth University
- Other
- Eligibility
- 21 Years to 99 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Richmond, Virginia
- Conditions
- Acute Decompensated Heart Failure
- Interventions
- Daily pocus exam
- Diagnostic Test
- Lead sponsor
- Riverside University Health System Medical Center
- Other
- Eligibility
- 18 Years to 95 Years
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Moreno Valley, California
- Conditions
- Cardiorenal Syndrome
- Interventions
- Milrinone, Dobutamine
- Drug
- Lead sponsor
- Maimonides Medical Center
- Other
- Eligibility
- 18 Years to 95 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016
- U.S. locations
- 1
- States / cities
- Brooklyn, New York
- Conditions
- Acute Decompensated Heart Failure, Obstructive Sleep Apnea, Motivational Enhancement, PAP Adherence
- Interventions
- Telemedicine Intensive Motivational Enhancement
- Behavioral
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Heart Failure, Decompensated Heart Failure, Acute Heart Failure
- Interventions
- CXL-1427, Placebo
- Drug
- Lead sponsor
- Bristol-Myers Squibb
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 14
- States / cities
- Gainesville, Florida • Jacksonville, Florida • Macon, Georgia + 10 more
- Conditions
- Heart Failure
- Interventions
- Non-invasive hemodynamic monitoring (CVInsight™ [CVI])
- Device
- Lead sponsor
- Intelomed, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Washington D.C., District of Columbia
- Conditions
- Acute Decompensated Heart Failure, Heart Failure
- Interventions
- Not listed
- Lead sponsor
- UConn Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2027
- U.S. locations
- 1
- States / cities
- Farmington, Connecticut
- Conditions
- Congestive Heart Failure(CHF), Pleural Effusion Due to Congestive Heart Failure
- Interventions
- Thoracentesis
- Procedure
- Lead sponsor
- Albany Medical College
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 216 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- Albany, New York
- Conditions
- Heart Failure, Volume Overload, Decompensated Heart Failure, Systolic Heart Failure
- Interventions
- Blood Collection, Blood Volume Analysis
- Procedure
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Acute Decompensated Heart Failure
- Interventions
- Loop diuretics (furosemide, torsemide, bumetanide), Ultrafiltration
- Drug · Other
- Lead sponsor
- University of Cincinnati
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 2
- States / cities
- Cincinnati, Ohio
- Conditions
- Acute Decompensated Heart Failure
- Interventions
- AVIVO™ PiiX Patch Monitor System
- Device
- Lead sponsor
- Medtronic Cardiac Rhythm and Heart Failure
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2013
- U.S. locations
- 7
- States / cities
- La Jolla, California • Tampa, Florida • Saint Paul, Minnesota + 4 more
- Conditions
- Acute Decompensated Heart Failure
- Interventions
- Neuromodulation
- Device
- Lead sponsor
- University of Oklahoma
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2026
- U.S. locations
- 1
- States / cities
- Oklahoma City, Oklahoma
- Conditions
- Acute Decompensated Heart Failure
- Interventions
- Furosemide Injection Solution 8mg/mL
- Drug
- Lead sponsor
- Todd M Koelling, MD
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Acute Heart Failure
- Interventions
- sacubitril/valsartan (LCZ696), Enalapril, sacubitril/valsartan (LCZ696) matching placebo, enalapril matching placebo
- Drug
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 887 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 123
- States / cities
- Birmingham, Alabama • Fort Smith, Arkansas • Little Rock, Arkansas + 105 more