Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:14 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 241–264 of 428 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Acute Kidney Insufficiency Clear all

Conditions: Acute Kidney Injury
Interventions: SCD; Device
Lead sponsor: SeaStar Medical; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 134 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 26
States / cities: Birmingham, Alabama • Los Angeles, California • San Diego, California + 21 more

Conditions: ACS - Acute Coronary Syndrome
Interventions: MT1002 for Injection; Drug
Lead sponsor: Shaanxi Micot Pharmaceutical Technology Co., Ltd.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 2 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Miami, Florida

Conditions: End Stage Liver DIsease, Obesity, Acute Kidney Injury
Interventions: Direct Peritoneal Resuscitation; Procedure
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Metabolic Acidosis, Acute Kidney Injury, Acute Kidney Failure
Interventions: Low bicarbonate solution (22 mmol/L), High Bicarbonate solution (32 mmol/L); Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 100 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Acute Kidney Injury, Renal Replacement Therapy, Pediatric Intensive Care Units
Interventions: Not listed
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 3 Months to 25 Years
Enrollment: 420 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2029
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Acute Kidney Injury, Critical Illness Myopathy, Dialysis; Complications
Interventions: Musculoskeletal ultrasound, Assessments of muscle strength and physical function, Metabolomics; Diagnostic Test
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years to 89 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 3
States / cities: Iowa City, Iowa • Lexington, Kentucky • Albuquerque, New Mexico

Conditions: Contrast-induced Nephropathy, Chronic Kidney Diseases
Interventions: Low-frequency therapeutic ultrasound (LOTUS), LOTUS System with Ultrasound Disabled; Device
Lead sponsor: Sonogenix; Industry
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 4
States / cities: Detroit, Michigan • Petoskey, Michigan • Pittsburgh, Pennsylvania + 1 more

Conditions: Acute Kidney Injury, Acute Kidney Injury Due to Sepsis, Neonatal Sepsis
Interventions: Renal Angina Index (RAI); Other
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: Up to 25 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Continuous Renal Replacement Therapy
Interventions: use of continuous renal replacement machine for renal replacement, use of blood volume monitoring device in conjunction with machine used for continuous renal replacement to assess and determine volume removal; Device
Lead sponsor: Dallas VA Medical Center; Federal
Eligibility: 21 Years and older
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Acute Kidney Failure
Interventions: Neseritide; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2007
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Regional Citrate Anticoagulation (RCA), Continuous Renal Replacement Therapy (CRRT), Acute Kidney Injury
Interventions: Prismocitrate 18, No Anticoagulation; Drug · Other
Lead sponsor: Vantive Health LLC; Industry
Eligibility: 18 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 11
States / cities: Birmingham, Alabama • Tucson, Arizona • New Haven, Connecticut + 8 more

Conditions: Acute Renal Failure
Interventions: N-acetylcysteine, Placebo; Drug
Lead sponsor: Baylor Research Institute; Other
Eligibility: 18 Years to 71 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2014
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Cirrhosis, Liver, Acute Kidney Injury, Hepatorenal Syndrome
Interventions: Recommendation: No Further Resuscitation, Recommendation: Resuscitation with Crystalloid, Recommendation: Resuscitation with Colloid, Recommendation: Standard of Care IV Albumin; Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Kidney Injury, Pre-Term
Interventions: Caffeine citrate, Placebo; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 12 Hours to 96 Hours
Enrollment: 114 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Acute Renal Failure, Kidney Disease, Coronary Artery Disease
Interventions: IV isotonic saline, IV isotonic bicarbonate, N-acetylcysteine, Placebo; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 5,177 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 35
States / cities: Tucson, Arizona • Little Rock, Arkansas • Palo Alto, California + 32 more

Conditions: Acute Kidney Injury
Interventions: Saline, Sodium Nitrite; Drug
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 19 Years to 100 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Acute Kidney Injury
Interventions: Urine collection for NEPHROCLEAR CCL14 Test; Diagnostic Test
Lead sponsor: Astute Medical, Inc.; Industry
Eligibility: 21 Years and older
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Acute Kidney Injury
Interventions: Not listed
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Cardiac Surgery, Coronary Artery Bypass Grafting, Valve Surgery, Kidney Injury
Interventions: AP214, Placebo; Drug
Lead sponsor: Action Pharma A/S; Industry
Eligibility: 18 Years and older
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 2
States / cities: Gainesville, Florida

Conditions: Acute Kidney Injury
Interventions: Brilliance device sensor; Device
Lead sponsor: MediBeacon; Industry
Eligibility: 18 Years to 99 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Acute Kidney Injury
Interventions: 0.9% Normal Saline (0.9% Sodium Chloride) injection, Isolyte S injection; Drug
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Cardiac Surgery, Acute Kidney Injury, Congenital Heart Disease, Aortic Surgery
Interventions: Acute normovolemic hemodilution (ANH); Biological
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Acute Kidney Injury
Interventions: Protonix (Pantoprazole) 40 mg q 12 hrs for 2 days, Protonix (pantoprazole) 40 mg q 24 hrs for 2 days; Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Type 2 Diabetes Mellitus, Acute Kidney Injury, Chronic Kidney Diseases
Interventions: Clinical Decision Support Message; Other
Lead sponsor: University of Minnesota; Other
Eligibility: 30 Years to 75 Years
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2032
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Search by objective public record fields.

Efficacy Study of a Selective Cytopheretic Device (SCD) in Patients With Acute Kidney Injury

Evaluate the Effects of Renal Impairment on the Pharmacokinetics and Pharmacodynamics

Use of Direct Peritoneal Resuscitation in High-risk Liver Transplant Recipients

High Versus Low Bicarbonate Bath in Critically-ill Patients Receiving Continuous Renal Replacement Therapy

Use of NGAL for Fluid Dosing and CRRT Initiation in Pediatric AKI

Critical Illness Myopathy and Trajectory of Recovery in AKI Requiring CRRT

Multi-Center Trial Utilizing Low Frequency Ultrasound in the Prevention of Post-Contrast Acute Kidney Injury

Use of NGAL for Fluid Dosing and CRRT Initiation in Pediatric and Neonatal AKI

Continuous Versus Conventional Volume Management During CRRT (Continuous Renal Replacement Therapy)

BNP (Nesiritide) vs. Placebo to Protect Kidney Function in Patients Undergoing Heart Bypass Surgery.

Clinical Evaluation of Use of Prismocitrate 18 in Patients Undergoing Acute Continuous Renal Replacement Therapy (CRRT)

Acute Renal Failure Post Liver Transplantation

Initial Resuscitation for Acute Kidney Injury in Cirrhosis

Improving Preterm Kidney Outcomes With Caffeine

Prevention of Serious Adverse Events Following Angiography

Nitrite Infusion in High Risk Patients Undergoing Cardiopulmonary Bypass

Urine Sample Processing Study

Noninvasive Measurements of Renal Perfusion During Cardiac Surgery

Safety, Tolerability and Pharmacodynamics of AP214 Acetate in Patients Undergoing Cardiac Surgery

Tolerability and Background Fluorescence of the MediBeacon Transdermal GFR Measurement System

Fluid Chloride and AKI in Cardiopulmonary Bypass

Acute Normovolemic Hemodilution in Complex Cardiac Surgery

Comparison of Early Proton Pump Inhibitor Initiation Versus Usual Care on Acute Kidney Injury in Hemorrhagic Shock Patients

Clinical Decision Support for SGLT2i After AKI in Type 2 Diabetes