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ClinicalTrials.gov public records Last synced Nov 15, 2026, 8:10 AM EST

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Showing 49–72 of 428 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Acute Kidney Insufficiency Clear all

Conditions: Acute Kidney Injury
Interventions: Auxora, Placebo; Drug
Lead sponsor: CalciMedica, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 122 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 33
States / cities: Birmingham, Alabama • Chandler, Arizona • Little Rock, Arkansas + 28 more

Conditions: Endothelial Dysfunction, Acute Kidney Injury
Interventions: Not listed
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 50 Years to 70 Years
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Acute Kidney Injury, Congenital Heart Disease
Interventions: Sodium Bicarbonate, Sodium Chloride; Drug
Lead sponsor: Northwell Health; Other
Eligibility: Up to 21 Years
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: New Hyde Park, New York

Conditions: Acute Kidney Injury
Interventions: Creatine Monohydrate, Creatine Ethyl Ester; Dietary Supplement
Lead sponsor: Beth Israel Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009
U.S. locations: 1
States / cities: New York, New York

Conditions: Acute Kidney Injury
Interventions: Education, Education and follow-up; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Heart Failure
Interventions: Stepped pharmacologic care, Ultrafiltration; Drug · Device
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 188 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 8
States / cities: Phoenix, Arizona • Atlanta, Georgia • Minneapolis, Minnesota + 5 more

Conditions: Acute Kidney Failure
Interventions: Furosemide; Drug
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2022
U.S. locations: 4
States / cities: San Francisco, California • Washington D.C., District of Columbia • Chicago, Illinois + 1 more

Conditions: Kidney Failure, Acute, Renal Insufficiency
Interventions: Not listed
Lead sponsor: Yale University; Other
Eligibility: Not listed
Enrollment: 1,550 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2014
U.S. locations: 6
States / cities: Denver, Colorado • Danbury, Connecticut • New Haven, Connecticut + 3 more

Conditions: AKI, AKI - Acute Kidney Injury, Dialysis Patients
Interventions: Transmission of additional AKI-D recovery information, No additional AKI-D recovery information; Behavioral · Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Acute Kidney Injury
Interventions: Early Nephrology Consult (ENC), Standard of Care (SOC); Other
Lead sponsor: University of Chicago; Other
Eligibility: 18 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Acute Kidney Injury
Interventions: RMC-035, Placebo; Drug
Lead sponsor: Guard Therapeutics AB; Industry
Eligibility: 18 Years to 84 Years
Enrollment: 177 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 8
States / cities: Fort Wayne, Indiana • Lincoln, Nebraska • Rochester, New York + 5 more

Conditions: Acute Kidney Injury (AKI)
Interventions: ASP1128, Placebo; Drug
Lead sponsor: Astellas Pharma Inc; Industry
Eligibility: 35 Years and older
Enrollment: 351 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 27
States / cities: Huntsville, Alabama • Tucson, Arizona • Clearwater, Florida + 23 more

Conditions: Acute Renal Failure
Interventions: Not listed
Lead sponsor: Asha Moudgil; Other
Eligibility: 1 Year to 21 Years
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Acute Kidney Injury
Interventions: ProNephro AKI™ (NGAL); Diagnostic Test
Lead sponsor: BioPorto Diagnostics; Industry
Eligibility: 22 Years and older
Enrollment: 800 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 4
States / cities: Birmingham, Alabama • New Haven, Connecticut • Boston, Massachusetts + 1 more

Conditions: Acute Kidney Injury, Inflammation
Interventions: Blue light; Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Urinary Retention, Acute Kidney Injury
Interventions: Bladder Volume Measurement bladder scanner RN, Bladder Volume Measurement Ultrasound APRN, Bladder Volume Measurement bladder scanner APRN, Bladder Volume Measurement Ultrasound MD, Intermittent Straight Catheterization; Other
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 90 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Acute Kidney Injury
Interventions: Not listed
Lead sponsor: Stanford University; Other
Eligibility: Up to 3 Months
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Acute Kidney Injury
Interventions: CXA-10, CXA-10 placebo; Drug · Other
Lead sponsor: Complexa, Inc.; Industry
Eligibility: 18 Years to 60 Years · Male only
Enrollment: 43 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 1
States / cities: Kalamazoo, Michigan

Conditions: Acute Kidney Injury
Interventions: AKI in Care Transitions (ACT) program; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: End Stage Renal Disease, Renal Transplant
Interventions: Anti-Thymocyte Globulin, TOL101, Steroids, Tacrolimus, Mycophenolate mofetil (MMF); Drug
Lead sponsor: Tolera Therapeutics, Inc; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 85 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 12
States / cities: Aurora, Colorado • Lexington, Kentucky • Ann Arbor, Michigan + 9 more

Conditions: Cirrhosis, Ascites, Hepatorenal Syndrome, Acute Kidney Injury
Interventions: OCE-205, Placebo; Drug
Lead sponsor: Ocelot Bio, Inc; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 22
States / cities: Phoenix, Arizona • Los Angeles, California • San Francisco, California + 18 more

Conditions: COVID, Severe Acute Respiratory Syndrome, Sars-CoV2, Acute Kidney Injury, Acute Respiratory Distress Syndrome
Interventions: LSALT peptide, Placebo; Drug
Lead sponsor: Arch Biopartners Inc.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 3
States / cities: San Diego, California • Fort Lauderdale, Florida • Shreveport, Louisiana

Conditions: NIRS, Cardiac Surgery Associated - Acute Kidney Injury, Cardiac Surgery Requiring Cardiopulmonary Bypass, AKI - Acute Kidney Injury
Interventions: NIRS sensor placement; Device
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Acute Renal Failure
Interventions: Renal tubule assist device; Device
Lead sponsor: RenaMed Biologics; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2007
U.S. locations: 13
States / cities: Birmingham, Alabama • Augusta, Georgia • Chicago, Illinois + 10 more

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A Study of Auxora in Patients With AKI and Injurious Lung "Crosstalk"

Optimizing Pulsatility During Cardiopulmonary Bypass

Sodium Bicarbonate to Prevent Acute Kidney Injury in Children Undergoing Cardiac Surgery

Effect of Creatine on Serum and Urine Creatinine

Enhanced Kidney Follow-up for AKI Survivors in Care Transitions

Effectiveness of Ultrafiltration in Treating People With Acute Decompensated Heart Failure and Cardiorenal Syndrome (The CARRESS Study)

The Effect of Loop Diuretics on Severity and Outcome of Acute Kidney Injury

Examining New Diagnostic Tests for Acute Kidney Injury After Heart Surgery

Outpatient Recovery From Acute Kidney Injury Requiring Dialysis - 2

An Early Real-Time Electronic Health Record Risk Algorithm for the Prevention and Treatment of Acute Kidney Injury

Efficacy and Safety of RMC-035 in Subjects at High Risk for Acute Kidney Injury Following Open-Chest Cardiac Surgery

Study to Evaluate the Efficacy of ASP1128 (MA-0217) in Subjects at Risk for Acute Kidney Injury (AKI) Following Coronary Artery Bypass Graft (CABG) and/or Valve Surgery

Carnitine, Aclycarnitine, Myocardial Function, and CRRT

ProNephro NGAL Test for Early Detection of Acute Kidney Injury in Adult ICU Patients (ALPACA)

Light Therapy in Cardiopulmonary Bypass Surgery

Measuring Bladder Volumes Scanning in the ICU

Pharmacology of Aminophylline for Acute Kidney Injury in Neonates

PK and PD of Sequential Multiple Ascending, Repeat Doses of Oral CXA-10 in Healthy Obese Male Subjects

A Study of Acute Kidney Injury in Care Transitions

Evaluating Safety and Efficacy of TOL101 Induction Versus Anti-Thymocyte Globulin to Prevent Kidney Transplant Rejection

A Study of OCE-205 in Participants With Cirrhosis With Ascites Who Developed Hepatorenal Syndrome-Acute Kidney Injury

LSALT Peptide vs. Placebo to Prevent ARDS and Acute Kidney Injury in Patients Infected With SARS-CoV-2 (COVID-19)

A Comparison of Renal vs Limb NIRS for Predicting Cardiac Surgery Associated Acute Kidney Injury

Open-Label Study To Evaluate the Safety and Efficacy of the Renal Assist Device In Patients With Acute Renal Failure