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ClinicalTrials.gov public records Last synced Nov 15, 2026, 9:06 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 121–144 of 428 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Acute Kidney Insufficiency Clear all

Conditions: Intermittent Hypoxemia, Acute Kidney Injury, Preterm Infant
Interventions: Not listed
Lead sponsor: Elie G. Abu Jawdeh, MD; Other
Eligibility: Up to 2 Months
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Kidney Disease, Nephropathy, Type 2 Diabetes
Interventions: losartan, lisinopril; Drug
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years and older
Enrollment: 1,448 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2014
U.S. locations: 30
States / cities: Phoenix, Arizona • Little Rock, Arkansas • Loma Linda, California + 27 more

Conditions: Acute Renal Failure (ARF), Acute Tubular Necrosis
Interventions: QRX-3; Drug
Lead sponsor: Ebima Clifford Okundaye; Industry
Eligibility: 10 Years to 80 Years
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Rosharon, Texas

Conditions: Heart Failure, Acute Kidney Injury
Interventions: Dapagliflozin 10mg Tab, Placebo; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 130 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 2
States / cities: New Haven, Connecticut

Conditions: Acute Kidney Injury
Interventions: Aminophylline, Placebo; Drug
Lead sponsor: Stanford University; Other
Eligibility: 1 Day to 18 Years
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Acute Kidney Injury, Hemolysis, Thrombocytopenia, Surgery
Interventions: Non-pulsatile blood flow, Pulsatile blood flow; Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 85 Years
Enrollment: 1,100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Ischemia Reperfusion Injury, Myocardial Injury, Acute Kidney Injury
Interventions: Niacinamide, Placebo; Drug
Lead sponsor: Kaiser Permanente; Other
Eligibility: 18 Years and older
Enrollment: 331 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Acute Kidney Injury, Cirrhosis, Decompensated Cirrhosis of Liver
Interventions: Droxidopa capsules, Placebo; Drug · Other
Lead sponsor: Giuseppe Cullaro, MD; Other
Eligibility: 18 Years to 70 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Liver Transplant, Hepatitis C, Chronic Kidney Disease, Acute Rejection
Interventions: Not listed
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2031
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Acute Kidney Injury
Interventions: Kidney Action Team Recommendations; Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 4,003 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Acute Kidney Injury
Interventions: Nitric Oxide, Placebo; Drug · Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Acute Kidney Injury, Fluid Overload, Ultrasonography
Interventions: Portal vein flow, Intra-renal flow, Hepatic vein flow, Pulmonary B-lines, Dimensions of the inferior vena cava, Left ventricular function, Right ventricular function; Diagnostic Test
Lead sponsor: Centre hospitalier de l'Université de Montréal (CHUM); Other
Eligibility: 18 Years and older
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Acute Kidney Injury, Chronic Kidney Diseases, Renal Dialysis
Interventions: CARPEDIEM; Device
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: Not listed
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2031
U.S. locations: 9
States / cities: Palo Alto, California • Aurora, Colorado • Atlanta, Georgia + 6 more

Conditions: Acute Kidney Injury
Interventions: Conventional management arm, AKI sniffer instigated AKI management; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 2,266 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2021
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Acute Kidney Injury, Fluid Overload, Hypotension, Dialysis; Complications, Critical Illness
Interventions: Restrictive UFnet Rate Strategy, Liberal UFnet Rate Strategy; Procedure
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 99 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 2
States / cities: Rochester, Minnesota • Pittsburgh, Pennsylvania

Conditions: Kidney Transplantation
Interventions: Lumason Contrast-Enhanced Ultrasound; Drug
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Kidney Injury, Acute
Interventions: Sodium Nitrate, Placebo; Drug
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Chronic Kidney Diseases, Vascular Function, Women
Interventions: S-equol, Placebo; Drug · Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 50 Years to 69 Years · Female only
Enrollment: 38 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Acute Kidney Injury
Interventions: Furosemide, Peritoneal Dialysis; Drug · Procedure
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: Up to 6 Months
Enrollment: 73 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Covid19, Outcome, Fatal, Respiratory Failure, Acute Kidney Injury, Inflammation
Interventions: SuPAR, C-reactive protein, Ferritin, D-Dimer, Procalcitonin, Interleukin-6, Lactate Dehydrogenase; Diagnostic Test
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 4,463 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Acute Kidney Injury
Interventions: Remote ischemic preconditioning; Procedure
Lead sponsor: Johns Hopkins University; Other
Eligibility: Not listed
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Renal Insufficiency, Congestive Heart Failure
Interventions: tonapofylline, Placebo; Drug
Lead sponsor: Biogen; Industry
Eligibility: 18 Years and older
Enrollment: 420 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 68
States / cities: Huntsville, Alabama • Mobile, Alabama • Fort Smith, Arkansas + 64 more

Conditions: Acute Kidney Injury
Interventions: Angiography; Procedure
Lead sponsor: Tulane University; Other
Eligibility: 18 Years to 100 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: New Orleans, Louisiana

Conditions: Covid19, AKI, CKD, ESRD, Transplant;Failure,Kidney
Interventions: Not listed
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 5
States / cities: Birmingham, Alabama • San Diego, California • Aurora, Colorado + 2 more

Search by objective public record fields.

Intermittent Hypoxemia and Acute Kidney Injury Study (IHAKI Study)

VA NEPHRON-D: Diabetes iN Nephropathy Study

Use of QRX3 for Acute Tubular Necrosis Type of Renal Failure in Hospitalized Patients ( QRX-3 in ARF)

Sodium-Glucose Cotransporter-2 Inhibitor for Patients With Acute Cardiorenal Syndrome

Aminophylline to Prevent Acute Kidney Injury in Children After Cardiac Surgery

Optimizing Pulsatility During Cardiopulmonary Bypass to Reduce Acute Kidney Injury

NAD+ Augmentation in Cardiac Surgery Associated Myocardial Injury Trial

Droxidopa to Increase Mean Arterial Pressure in Decompensated Cirrhosis Patients With Acute Kidney Injury

Proteogenomic Monitoring and Assessment of Liver Transplant Recipients

Personalized Recommendations for Acute Kidney Injury (AKI) Care

Effect of Nitric Oxide in Cardiac Surgery Patients With Endothelial Dysfunction.

Ultrasound Markers of Organ Congestion in Severe Acute Kidney Injury

Improving Continuous Renal Replacement Therapy Outcomes in Neonates and Infants Through Interdisciplinary Collaboration

PRevention of Acute Kidney Injury Initiated With Electronic Surveillance Enhancement

Restrictive Versus Liberal Rate of Extracorporeal Volume Removal Evaluation in Acute Kidney Injury

Contrast-Enhanced Ultrasound for Kidney Transplant

Inorganic Nitrate (NaNO3) Prevention of Contrast-Associated Acute Kidney Injury

Acute Equol Supplementation and Vascular Function in Women With and Without CKD

Peritoneal Dialysis vs Furosemide for Acute Kidney Injury After Cardiopulmonary Bypass

International Study of Inflammation in COVID-19

Remote Ischemic Preconditioning to Prevent Contrast Nephropathy

Study to Assess the Safety and Tolerability of IV Tonapofylline in Subjects With Acute Decompensated Heart Failure (ADHF) and Renal Insufficiency

Ultra-Low Contrast Angiography in AKI

Global Assessment of Acute and Chronic Kidney Disease Incidence and Outcomes in Patients With COVID-19 Infection