Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 15, 2026, 9:53 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 169–192 of 428 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Acute Kidney Insufficiency Clear all

Conditions: Acute Kidney Injury
Interventions: Protonix (Pantoprazole) 40 mg q 12 hrs for 3 days, Pepcid (Famotidine) 20 mg q 12 hrs for 3 days; Drug
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years to 90 Years
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic, Leukemia, Myeloid, Acute, Renal Insufficiency, Liver Disease, Neoplasms
Interventions: Azacitidine, Pevonedistat; Drug
Lead sponsor: Takeda; Industry
Eligibility: 18 Years and older
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 2
States / cities: New York, New York • Chapel Hill, North Carolina

Conditions: Acute Heart Failure, Acute Renal Failure
Interventions: BARD® Intra-abdominal Pressure monitor; Device
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Staten Island, New York

Conditions: Chronic Disease, Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight, Hypertension, Cardiovascular Disease Acute, Hyperlipidemia, Chronic Kidney Disease (CKD), Stages 3-4 Exercise Tolerance / Functional Capacity Vascular Health / Arterial Stiffness Fatigue in CKD, Peripheral Artery Disease, Metabolic Syndrome, Prediabetes
Interventions: Truway Portable Ultrasound Device, Truway Blood Glucose Monitor, Standard Oral Hypoglycemic Agent; Device · Drug
Lead sponsor: Truway Health, Inc.; Industry
Eligibility: Not listed
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Kidney Failure, Chronic
Interventions: Thymoglobulin, Daclizumab, Plasmapheresis, Mycophenolate mofetil, Tacrolimus, Dexamethasone, Prednisone, Cytogam; Drug · Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Kidney Failure, Acute, Renal Insufficiency, Acute, Kidney Failure, Renal Insufficiency
Interventions: Early Renal Involvement; Other
Lead sponsor: Saint Louis VA Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Postoperative Complications
Interventions: Risk estimation; Other
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 100 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2028
U.S. locations: 2
States / cities: Gainesville, Florida • Jacksonville, Florida

Conditions: Acute Kidney Injury
Interventions: Alert; Other
Lead sponsor: Yale University; Other
Eligibility: 18 Years and older
Enrollment: 2,046 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Biomarkers, Acute Kidney Injury, Sepsis
Interventions: Not listed
Lead sponsor: Nutromics; Industry
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 5
States / cities: Oakland, California • San Francisco, California • Stanford, California + 2 more

Conditions: Renal Dysfunction, Acute Renal Failure, Mortality
Interventions: URODILATIN (ULARITIDE, ATRIAL NATRIURETIC PEPTIDE), MANNITOL; Drug
Lead sponsor: Rocky Mountain Cancer Centers; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2006
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Acute Kidney Injury, COVID
Interventions: Not listed
Lead sponsor: Children's Healthcare of Atlanta; Other
Eligibility: 7 Days to 25 Years
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 33
States / cities: Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 29 more

Conditions: Pneumonia, Syncope, Congestive Heart Failure, Cellulitis, Pyelonephritis, AKI - Acute Kidney Injury, Diabetic Foot Infection, Osteomyelitis
Interventions: Next Day Clinic; Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 570 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Acute Myocardial Infarction, Moderate Renal Impairment
Interventions: CSL_112, Placebo; Biological · Other
Lead sponsor: CSL Behring; Industry
Eligibility: 18 Years and older
Enrollment: 83 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 13
States / cities: Birmingham, Alabama • Huntsville, Alabama • Concord, California + 10 more

Conditions: Renal Insufficiency, Acute
Interventions: Not listed
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 90 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 2
States / cities: Aurora, Colorado • Seattle, Washington

Conditions: Kidney Failure, Acute, Renal Replacement Therapy
Interventions: Sodium bicarbonate, Normal saline, Bicarbonate, Placebo; Drug · Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 123 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2013
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Surgeries Undergoing General Anesthesia
Interventions: Lower FiO2, Intermediate FiO2, Higher FiO2; Other
Lead sponsor: Frederic T Billings IV; Other
Eligibility: 18 Years and older
Enrollment: 54,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 4
States / cities: Ann Arbor, Michigan • Omaha, Nebraska • Nashville, Tennessee + 1 more

Conditions: End Stage Kidney Disease, End Stage Renal Disease, Acute Kidney Injury
Interventions: Intermittent Renal Replacement Therapy using the Tablo Hemodialysis System, Intermittent Renal Replacement Therapy using Conventional Hemodialysis Systems; Device
Lead sponsor: Outset Medical; Industry
Eligibility: 18 Years and older
Enrollment: 458 participants
Timeline: 2021 – 2022
U.S. locations: 2
States / cities: Orlando, Florida • Fort Worth, Texas

Conditions: Acute Kidney Failure
Interventions: ertapenem; Drug
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Acute Renal Failure
Interventions: Fenoldopam Mesylate and/or MESNA; Drug
Lead sponsor: Southeast Renal Research Institute; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 2
States / cities: Washington D.C., District of Columbia • Chattanooga, Tennessee

Conditions: Heart Decompensation, Acute, Acute Kidney Injuries
Interventions: Furosemide (Standard Diuretic) Treatment, POCUS-Assessed Diuretic Management; Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 588 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 5
States / cities: Pittsburgh, Pennsylvania

Conditions: Fluid Balance, Input and Output, Inflammatory Mediators, Acute Kidney Injury, Mortality
Interventions: Not listed
Lead sponsor: University of Florida; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Critical Illness, Acute Kidney Injury
Interventions: 0.9% Saline, Physiologically-balanced isotonic crystalloid; Other
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years and older
Enrollment: 10,421 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Acute Kidney Injury
Interventions: Niyad (nafamostat mesylate), Placebo (0.9% NaCl); Device
Lead sponsor: Talphera, Inc; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 10
States / cities: Los Angeles, California • Orlando, Florida • Detroit, Michigan + 7 more

Conditions: Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis, Acute Pancreatitis, Rheumatoid Arthritis, Diabetes Mellitus, Dyslipidemias, Multiple Sclerosis, Irritable Bowel Syndrome, Chronic Pain, Chronic Disease, Chronic Kidney Diseases, Crohn Disease, Celiac Disease, Biliary Cirrhosis, Bile Acid Synthesis Defect, Gastritis, Cholecystitis, Cholelithiases, IPMN, Cyst Pancreas, Cystic Fibrosis, Pancreatic Exocrine Insufficiency, Diarrhea Chronic, Constipation - Functional, Constipation Chronic Idiopathic
Interventions: venipuncture, Questionnaires, Additional Sample Collections; Other · Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 12 Years and older
Enrollment: 120,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2026
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Search by objective public record fields.

Post-Cardiac Surgery Acute Kidney Injury Prevention by Administration of Proton Pump Inhibitor (P2 Trial)

A Study of Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems

Bladder Pressure Predicting Renal Failure in Critically Ill Patients as Compared to Hemodynamic Parameters

Truway Diagnostic Tools in Primary Care

Induction Therapy Study in Live Donor Kidney Transplant Recipients With a Positive Crossmatch

Impact of Early Renal Involvement on the Development of Severe In-hospital Renal Failure

Integrating Data, Algorithms and Clinical Reasoning for Surgical Risk Assessment

Learning Alerts for Acute Kidney Injury

Vancomycin Exposure and Biomarker Tracking Using Real-time Monitoring of Interstitial Fluid

Prevention Of Nephrotoxicity Following Bone Marrow Transplantation Using Urodilatin and Mannitol

Pediatric Acute Kidney Injury in COVID-19

Quasi-Randomized Evaluation of the UCLA Next Day Clinic (NDC)

A Study of CSL112 in Adults With Moderate Renal Impairment and Acute Myocardial Infarction

New Urine and Blood Markers for Acute Kidney Injury in Liver Transplant Patients

Use of Bicarbonate to Reduce the Incidence of Acute Renal Failure After Cardiac Surgery

Impact of Intraoperative Oxygenation Practices on Patient Outcomes

Comparative Outcome Measures of Patients Receiving Acute Renal ThErapy Study

Pharmacokinetics of Ertapenem in Continuous Venovenous Hemodialysis

Vasodilators and Anti-Oxidant Therapy in Early ATN

POCUS-Guided Diuresis for Decompensated Heart Failure

Fluid Balance and Clinical Outcomes

Isotonic Solutions and Major Adverse Renal Events Trial in the Non-Medical Intensive Care Unit (SMART-SURG)

Nafamostat Efficacy in Phase 3 Registrational CRRT Study

Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study