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ClinicalTrials.gov public records Last synced Oct 29, 2026, 7:03 AM EDT

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Showing 25–48 of 108 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Acute Respiratory Illness Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Echinacea and Acute Respiratory Illness

NCT02003651
View directory record Official record
Conditions
Acute Respiratory Infections
Interventions
Quick Defense, Placebo
Dietary Supplement
Lead sponsor
Appalachian State University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 13, 2016 · Synced Oct 29, 2026, 7:03 AM EDT
Recruiting Phase 3 Interventional

Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome

NCT06066502
View directory record Official record
Conditions
Acute Respiratory Distress Syndrome, Respiratory Failure
Interventions
Precision ventilation, Guided usual care ventilation
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
1,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
33
States / cities
Tucson, Arizona • Little Rock, Arkansas • La Jolla, California + 25 more
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 29, 2026, 7:03 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Colorado-Oregon Altitude Study

NCT05734716
View directory record Official record
Conditions
Acute Mountain Sickness
Interventions
Erythropoietin, Iron sucrose (Venofer), Sterile Sodium Chloride
Drug
Lead sponsor
University of Oregon
Other
Eligibility
18 Years to 40 Years
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
Leadville, Colorado • Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 10, 2023 · Synced Oct 29, 2026, 7:03 AM EDT
Not yet recruiting Not applicable Interventional

ICU-SUCCEED for Survivors of Acute Respiratory Failure and Their Caregivers

NCT07778004
View directory record Official record
Conditions
Acute Respiratory Failure, Critical Illness, Sepsis, Hypoxia, Hypercapnia
Interventions
ICU-SUCCEED, Augmented Usual Care
Behavioral · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 29, 2026, 7:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Gut-microbiota Targeted Nutritional Intervention for Gut Barrier Integrity at High Altitude

NCT04111263
View directory record Official record
Conditions
Gastrointestinal Injury, Acute Mountain Sickness
Interventions
FP, Placebo, High altitude, Sea level
Dietary Supplement · Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
17 Years to 39 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 23, 2022 · Synced Oct 29, 2026, 7:03 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Apple Respiratory Study

NCT04912180
View directory record Official record
Conditions
Acute Respiratory Infection, Coronavirus Infection, Influenza
Interventions
Not listed
Lead sponsor
Apple Inc.
Industry
Eligibility
22 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 14, 2021 · Synced Oct 29, 2026, 7:03 AM EDT
Not yet recruiting Not applicable Interventional

Optimizing Dysphagia Treatment Delivery in Acute Care: A Hybrid Efficacy Implementation Trial

NCT07736105
View directory record Official record
Conditions
Dysphagia, Critical Illness
Interventions
Expiratory muscle strength training (EMST), Standard of Care Dysphagia Treatment, Intensive Dysphagia Treatment
Device · Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 29, 2026, 7:03 AM EDT
Active, not recruiting Not applicable Interventional

tVNS in Long COVID-19

NCT06585254
View directory record Official record
Conditions
Long COVID, Chronic Fatigue Syndrome
Interventions
Transcutaneous vagus nerve stimulator
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
21 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 29, 2026, 7:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Wells and Enteric Disease Transmission Trial (WET - Trial)

NCT04258059
View directory record Official record
Conditions
Gastrointestinal Infection, Respiratory Viral Infection
Interventions
Active household UV water treatment device, Inactive household UV water treatment device
Device
Lead sponsor
Temple University
Other
Eligibility
6 Months to 59 Months
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 29, 2026, 7:03 AM EDT
Terminated Phase 2 Interventional Results available

Study of Nitazoxanide in Adults With Acute Uncomplicated Influenza

NCT01056380
View directory record Official record
Conditions
Influenza
Interventions
Nitazoxanide, Placebo
Drug
Lead sponsor
Romark Laboratories L.C.
Industry
Eligibility
18 Years to 65 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Elmira, New York
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Oct 29, 2026, 7:03 AM EDT
Enrolling by invitation Not applicable Interventional

Examination of Personalized SpO2 Targets

NCT07536984
View directory record Official record
Conditions
Acute Respiratory Failure
Interventions
Personalized SpO2 Target, Usual Care
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 29, 2026, 7:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

FluSAFE: Flu SMS Alerts to Freeze Exposure

NCT03274310
View directory record Official record
Conditions
Influenza, Acute Respiratory Infection, Influenza-like Illness
Interventions
Educational text messages
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
Not listed
Enrollment
1,918 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 16, 2025 · Synced Oct 29, 2026, 7:03 AM EDT
Completed Not applicable Interventional

TelePORT Pilot Study

NCT03926533
View directory record Official record
Conditions
Critical Illness, Acute Respiratory Distress Syndrome, Septic Shock
Interventions
Telehealth
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 3, 2023 · Synced Oct 29, 2026, 7:03 AM EDT
Completed Not applicable Interventional Results available

A Study Promoting Critical Illness Recovery in the Elderly

NCT02963558
View directory record Official record
Conditions
Acute Respiratory Distress Syndrome, Critical Illness, Critical Care
Interventions
cycle ergometry
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
55 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 18, 2024 · Synced Oct 29, 2026, 7:03 AM EDT
Recruiting Not applicable Interventional

Care for Veterans Post-COVID-19

NCT05787379
View directory record Official record
Conditions
Post-Acute COVID-19 Syndrome
Interventions
Concordant Care Training, Education Packet Training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
348 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
East Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 24, 2025 · Synced Oct 29, 2026, 7:03 AM EDT
Completed Phase 4 Interventional Results available

Randomized Trial of Sedative Choice for Intubation

NCT05277896
View directory record Official record
Conditions
Acute Respiratory Failure
Interventions
Ketamine, Etomidate
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
2,367 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
6
States / cities
Birmingham, Alabama • Aurora, Colorado • Denver, Colorado + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 25, 2026 · Synced Oct 29, 2026, 7:03 AM EDT
Completed Not applicable Interventional

Feeding the Critically Ill During Phases of Altered Redox Status

NCT03085615
View directory record Official record
Conditions
Acute Respiratory Distress Syndrome, Oxidative Stress, Euthyroid Sick Syndromes, Systemic Inflammatory Response Syndrome
Interventions
Jevity 1.5
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Oct 29, 2026, 7:03 AM EDT
Completed Not applicable Interventional

C-reactive Protein (CRP)-Guided Management Algorithm for Adults With Acute Cough

NCT00221351
View directory record Official record
Conditions
Cough
Interventions
CRP point of care testing
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
2
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated May 23, 2011 · Synced Oct 29, 2026, 7:03 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Efficacy of Prophylactic Treatment of Oral Prochlorperazine for Acute Mountain Sickness

NCT06310642
View directory record Official record
Conditions
AMS, Acute Mountain Sickness
Interventions
Immediate descent from altitude., Diphenhydramine, Prochlorperazine 10 mg
Other · Drug
Lead sponsor
CHRISTUS Health
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Corpus Christi, Texas
Source: ClinicalTrials.gov public record
Updated May 28, 2024 · Synced Oct 29, 2026, 7:03 AM EDT
Withdrawn No phase listed Observational

Airway Inflammatory Response During Illness in Children With Respiratory Failure

NCT02047877
View directory record Official record
Conditions
Acute Respiratory Failure, Acute Respiratory Infection, Acute Respiratory Distress Syndrome
Interventions
Not listed
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
Up to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 14, 2017 · Synced Oct 29, 2026, 7:03 AM EDT
Completed Not applicable Interventional Results available

Treatment of Critical Illness Polyneuromyopathy

NCT01058421
View directory record Official record
Conditions
Acute Respiratory Failure
Interventions
intensive physical therapy, control group
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
5
States / cities
Aurora, Colorado • Denver, Colorado • Englewood, Colorado + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2017 · Synced Oct 29, 2026, 7:03 AM EDT
Completed Not applicable Interventional Results available

DirEct Versus VIdeo LaryngosCopE Trial

NCT05239195
View directory record Official record
Conditions
Acute Respiratory Failure
Interventions
Video Laryngoscope, Direct Laryngoscope
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
1,420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
12
States / cities
Birmingham, Alabama • Aurora, Colorado • Denver, Colorado + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 19, 2024 · Synced Oct 29, 2026, 7:03 AM EDT
Completed Not applicable Interventional

Impact of a Multiplex Respiratory PCR Test on Outcomes for Patients Presenting With Respiratory Illness in the Urgent Care Setting: A Hybrid-Effectiveness Quasi-Experimental Trial

NCT07513519
View directory record Official record
Conditions
Acute Respiratory Infections (ARIs)
Interventions
SPOTFIRE R/ST Diagnostic Test
Device
Lead sponsor
BioMérieux
Industry
Eligibility
1 Year and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Gardendale, Alabama • Hoover, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 29, 2026, 7:03 AM EDT
Enrolling by invitation Not applicable Interventional

Hyperangulated Versus Standard Geometry Laryngoscope Blade Trial

NCT07223762
View directory record Official record
Conditions
Acute Respiratory Failure
Interventions
Hyperangulated video laryngoscope blade, Standard geometry video laryngoscope blade
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
2,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
19
States / cities
Birmingham, Alabama • Los Angeles, California • Stanford, California + 15 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 29, 2026, 7:03 AM EDT