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ClinicalTrials.gov public records Last synced Oct 17, 2026, 10:41 PM EDT

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Showing 25–48 of 138 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Adenoma Colon Polyp Clear all
Completed No phase listed Observational Accepts healthy volunteers

Study of a Screening Blood Test to Determine Patients' Potential Risk of Adenomatous or Advanced Colon Polyps (ACPs)

NCT01062035
View directory record Official record
Conditions
Colonic Polyp
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
50 Years to 60 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 26, 2014 · Synced Oct 17, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Narrow Band Imaging Colon Polyp Study

NCT00614770
View directory record Official record
Conditions
Adenomatous Polyp, New Imaging Techniques in Colonoscopy
Interventions
standard of care colonoscopy, colonoscopy
Procedure
Lead sponsor
Kansas City Veteran Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
630 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
2
States / cities
Kansas City, Missouri • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 17, 2010 · Synced Oct 17, 2026, 10:41 PM EDT
Completed No phase listed Observational

Collecting Information From Patients and Family Members With Hereditary Colorectal Cancer Syndromes or Who Are at High Risk of Developing Colorectal Cancer

NCT00675636
View directory record Official record
Conditions
Colorectal Cancer, Hereditary Non-polyposis Colon Cancer, Precancerous Condition
Interventions
study of socioeconomic and demographic variables, evaluation of cancer risk factors, study of high risk factors
Other · Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
Up to 100 Years
Enrollment
730 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2017
U.S. locations
3
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 2, 2017 · Synced Oct 17, 2026, 10:41 PM EDT
Completed Not applicable Interventional

Computer Aided Detection of Polyps in Colonoscopy

NCT04754347
View directory record Official record
Conditions
Colorectal Polyp
Interventions
Computer Aided Detection device
Device
Lead sponsor
Iterative Scopes, Inc
Industry
Eligibility
40 Years and older
Enrollment
1,472 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
5
States / cities
Boston, Massachusetts • Cambridge, Massachusetts • Plymouth, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 1, 2021 · Synced Oct 17, 2026, 10:41 PM EDT
Completed Phase 3 Interventional

Celecoxib to Prevent Colorectal Cancer in Patients Who Have Undergone Surgery to Remove Polyps

NCT00005094
View directory record Official record
Conditions
Colon Cancer, Rectal Cancer
Interventions
celecoxib, placebo
Drug · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
30 Years and older
Enrollment
1,170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2000
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 12, 2013 · Synced Oct 17, 2026, 10:41 PM EDT
Completed Phase 2 Interventional Results available

A Clinical Trial of COX and EGFR Inhibition in Familial Polyposis Patients

NCT01187901
View directory record Official record
Conditions
Adenomatous Polyposis Coli
Interventions
Erlotinib, Sulindac, Placebo A, Placebo B
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 69 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 17, 2016 · Synced Oct 17, 2026, 10:41 PM EDT
Completed Not applicable Interventional

Computer Aided Detection of Polyps in the Colon

NCT03925337
View directory record Official record
Conditions
Polyp, Adenomatous, Colo-rectal Cancer
Interventions
Computer Aided Diagnostic Software
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
22 Years and older
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
4
States / cities
Chicago, Illinois • Boston, Massachusetts • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 20, 2021 · Synced Oct 17, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Comparison of Methods to Detect Polyps During Colonoscopy

NCT01025960
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Standard Inspection Colonoscopy, Dual Inspection Colonoscopy
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
768 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 27, 2012 · Synced Oct 17, 2026, 10:41 PM EDT
Completed Not applicable Interventional

Combined Chromoendoscopy and Water Method for Screening Colonoscopy

NCT01383265
View directory record Official record
Conditions
Colon Polyp
Interventions
Water method and chromoendoscopy, Water method
Procedure
Lead sponsor
VA Northern California Health Care System
Federal
Eligibility
50 Years to 75 Years
Enrollment
1,177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Mather, California
Source: ClinicalTrials.gov public record
Updated Jun 17, 2013 · Synced Oct 17, 2026, 10:41 PM EDT
Completed Not applicable Interventional

Impact of Artificial Intelligence on Trainee Polyp Miss Rates

NCT06676930
View directory record Official record
Conditions
Colon Polyps, Colonoscopy, Artificial Intelligence (AI)
Interventions
Colonoscopy With Computer-Aided Detection, Colonoscopy without Computer-Aided Detection
Device · Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 17, 2026, 10:41 PM EDT
Completed Phase 2 Interventional Results available

Trial of Metformin for Colorectal Cancer Risk Reduction for History of Colorectal Adenomas and Elevated BMI

NCT01312467
View directory record Official record
Conditions
Adenomatous Polyp, Colorectal Cancer, Obesity
Interventions
metformin hydrochloride
Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
35 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
3
States / cities
Long Beach, California • Orange, California • Sacramento, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2019 · Synced Oct 17, 2026, 10:41 PM EDT
Terminated Phase 3 Interventional Results available

Rosuvastatin in Treating Patients With Stage I or Stage II Colon Cancer That Was Removed By Surgery

NCT01011478
View directory record Official record
Conditions
Colorectal Cancer, Precancerous Condition
Interventions
rosuvastatin, placebo
Drug · Other
Lead sponsor
NSABP Foundation Inc
Network
Eligibility
18 Years and older
Enrollment
406 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
584
States / cities
Anniston, Alabama • Mobile, Alabama • Fort Smith, Arkansas + 423 more
Source: ClinicalTrials.gov public record
Updated Aug 16, 2023 · Synced Oct 17, 2026, 10:41 PM EDT
Not listed No phase listed Observational

Effect of a Tracking Program on Colon Adenoma Surveillance and Adherence to Guideline Recommendations

NCT01713881
View directory record Official record
Conditions
Colon Polyp Surveillance
Interventions
Not listed
Lead sponsor
United States Department of Defense
Federal
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Fort Gordon, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 20, 2014 · Synced Oct 17, 2026, 10:41 PM EDT
Completed Phase 3 Interventional Results available

Trial of Eflornithine Plus Sulindac in Patients With Familial Adenomatous Polyposis (FAP)

NCT01483144
View directory record Official record
Conditions
Familial Adenomatous Polyposis
Interventions
Eflornithine, Eflornithine Placebo, Sulindac 150 MG, Sulindac placebo
Drug
Lead sponsor
Cancer Prevention Pharmaceuticals, Inc.
Industry
Eligibility
18 Years and older
Enrollment
171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
10
States / cities
La Jolla, California • Atlanta, Georgia • Boston, Massachusetts + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2021 · Synced Oct 17, 2026, 10:41 PM EDT
Terminated Not applicable Interventional

Step Down Colon Cancer Risk

NCT01476631
View directory record Official record
Conditions
Adenomatous Polyps
Interventions
Walking
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
50 Years to 80 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 5, 2013 · Synced Oct 17, 2026, 10:41 PM EDT
Terminated No phase listed Observational

Ileal Pouch-Anal Anastomosis Registry

NCT01026480
View directory record Official record
Conditions
Ileal Pouch-Anal Anastomosis
Interventions
Not listed
Lead sponsor
Boston Medical Center
Other
Eligibility
Not listed
Enrollment
936 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2017 · Synced Oct 17, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Computer Aided Detection of Polyps During Colonoscopy Procedures

NCT04195646
View directory record Official record
Conditions
Colo-rectal Cancer, Polyp of Colon, Adenomatous Polyps
Interventions
EndoVigilant CAD Software
Device
Lead sponsor
EndoVigilant Inc
Industry
Eligibility
18 Years to 85 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
2
States / cities
Palo Alto, California • Greenbelt, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 2, 2021 · Synced Oct 17, 2026, 10:41 PM EDT
Recruiting Phase 1Phase 2 Interventional

FOG-001 in Locally Advanced or Metastatic Solid Tumors

NCT05919264
View directory record Official record
Conditions
Cancer, Colorectal Cancer, Solid Tumor, Locally Advanced Solid Tumor, Metastatic Cancer, WNT Pathway, HCC, Desmoid, Microsatellite Stable Colorectal Cancer, Metastatic Castration-resistant Prostate Cancer, Familial Adenomatous Polyposis (FAP), Endometrial Carcinoma, Prostate Cancer, Microsatellite Instability-High Colorectal Cancer, Adamantinomatous Craniopharyngioma
Interventions
FOG-001, mFOLFOX-6, Nivolumab, Trifluridine/tipiracil, Bevacizumab
Drug
Lead sponsor
Parabilis Medicines, Inc.
Industry
Eligibility
18 Years and older
Enrollment
619 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
31
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Tucson, Arizona + 25 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 17, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Quad Resection (Hot Snare vs Cold Snare vs Hot EMR vs Cold EMR)

NCT03462706
View directory record Official record
Conditions
Colon Cancer, Colon Polyp, Colon Adenoma
Interventions
Cold Snare, Hot Snare, Cold EMR, Hot EMR
Procedure
Lead sponsor
Indiana University
Other
Eligibility
40 Years and older
Enrollment
238 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 15, 2023 · Synced Oct 17, 2026, 10:41 PM EDT
Completed Phase 2 Interventional Results available

Macrogol 3350-based Oral Osmotic Laxative in Preventing Cancer in Patients at Risk of Colorectal Cancer

NCT00828984
View directory record Official record
Conditions
Adenomatous Polyp, Colorectal Carcinoma
Interventions
macrogol 3350-based oral osmotic laxative, Placebo, Laboratory Biomarker Analysis
Drug · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
3
States / cities
Chicago, Illinois • Evanston, Illinois • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Oct 17, 2026, 10:41 PM EDT
Recruiting No phase listed Observational

GelPOINT® Path-Assisted Endoscopic Removal of Colon and Rectal Polyps: A Feasibility and Safety Study

NCT07723937
View directory record Official record
Conditions
Polyp Colorectal, Rectal Adenoma, Adenoma Colon Polyp
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 17, 2026, 10:41 PM EDT
Active, not recruiting Phase 2 Interventional

Trial of ERapa to Prevent Progression in Familial Adenomatous Polyposis Patients Under Active Surveillance

NCT04230499
View directory record Official record
Conditions
Familial Adenomatous Polyposis
Interventions
Encapsulated Rapamycin (eRapa)
Drug
Lead sponsor
Rapamycin Holdings Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
4
States / cities
Ann Arbor, Michigan • Cleveland, Ohio • Columbus, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 9, 2025 · Synced Oct 17, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Does Inspection During Insertion Improve Adenoma Yields During Colonoscopy?

NCT01035775
View directory record Official record
Conditions
Colorectal Cancer, Colorectal Polyps
Interventions
Inspection during insertion, Inspection during withdrawal
Procedure
Lead sponsor
Indiana University
Other
Eligibility
50 Years and older
Enrollment
340 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
2
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 16, 2018 · Synced Oct 17, 2026, 10:41 PM EDT
Recruiting No phase listed Observational

Evaluating Adenoma Recurrence After Endoscopic Mucosal Resection With Margin Marking or Post Treatment With Snare Tip Soft Coagulation

NCT06476145
View directory record Official record
Conditions
Adenoma Colon Polyp
Interventions
Not listed
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
342 participants
Timeline
2023 – 2027
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Oct 17, 2026, 10:41 PM EDT