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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Adenoma Colon Polyp Clear all
Completed Phase 3 Interventional

Celecoxib to Prevent Colorectal Cancer in Patients Who Have Undergone Surgery to Remove Polyps

NCT00005094
View directory record Official record
Conditions
Colon Cancer, Rectal Cancer
Interventions
celecoxib, placebo
Drug · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
30 Years and older
Enrollment
1,170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2000
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 11, 2013 · Synced Sep 1, 2026, 10:04 PM EDT
Completed Phase 2 Interventional Results available

Molecular Targeting of 15-Lipoxygenase-1 (15-LOX-1) for Apoptosis Induction in Human Colorectal Cancers

NCT00503035
View directory record Official record
Conditions
Familial Adenomatous Polyposis
Interventions
Celecoxib, Colonoscopy Biopsy
Drug · Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
16 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 12, 2023 · Synced Sep 1, 2026, 10:04 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Aspirin/Folate Prevention of Large Bowel Polyps

NCT00272324
View directory record Official record
Conditions
Colorectal Cancer, Polyps, Adenomas
Interventions
Aspirin, Folate
Drug
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
21 Years to 80 Years
Enrollment
1,121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1992 – 2007
U.S. locations
8
States / cities
Los Angeles, California • Denver, Colorado • Iowa City, Iowa + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 12, 2020 · Synced Sep 1, 2026, 10:04 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Enchasing Polyp Detection: The Effect of Adding Polyp Detection Attachment Device to Computer Aid Detection System.

NCT06116864
View directory record Official record
Conditions
Colon Cancer Screening, Colon Cancer Surveillance
Interventions
Endocuff and GI Genius, GI Genius
Device
Lead sponsor
Marshall University
Other
Eligibility
18 Years and older
Enrollment
1,766 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Huntington, West Virginia
Source: ClinicalTrials.gov public record
Updated Nov 2, 2023 · Synced Sep 1, 2026, 10:04 PM EDT
Completed Phase 3 Interventional Results available

Trial of Eflornithine Plus Sulindac in Patients With Familial Adenomatous Polyposis (FAP)

NCT01483144
View directory record Official record
Conditions
Familial Adenomatous Polyposis
Interventions
Eflornithine, Eflornithine Placebo, Sulindac 150 MG, Sulindac placebo
Drug
Lead sponsor
Cancer Prevention Pharmaceuticals, Inc.
Industry
Eligibility
18 Years and older
Enrollment
171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
10
States / cities
La Jolla, California • Atlanta, Georgia • Boston, Massachusetts + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 7, 2021 · Synced Sep 1, 2026, 10:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Third Eye Retroscope Randomized Clinical Evaluation

NCT01044732
View directory record Official record
Conditions
Colorectal Neoplasms
Interventions
Third Eye Retroscope
Device
Lead sponsor
Avantis Medical Systems
Industry
Eligibility
Not listed
Enrollment
448 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
5
States / cities
Baltimore, Maryland • Kansas City, Missouri • Lebanon, New Hampshire + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 24, 2017 · Synced Sep 1, 2026, 10:04 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Prevalence and Topography of Adenomas in 40-49 Year Old Patients With a Family History of Colon Cancer

NCT02289053
View directory record Official record
Conditions
Colorectal Cancer, Colon Polyps, Adenomatous Polyp of Colon
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
40 Years to 49 Years
Enrollment
1,623 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2014
U.S. locations
6
States / cities
Bethesda, Maryland • Ann Arbor, Michigan • Detroit, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated May 14, 2017 · Synced Sep 1, 2026, 10:04 PM EDT
Recruiting Phase 1 Interventional

Testing for Safety and Colorectal Cancer Preventive Effects of ONC201

NCT05630794
View directory record Official record
Conditions
Colorectal Adenomatous Polyp, Colorectal Carcinoma, Familial Adenomatous Polyposis, Multiple Adenomatous Polyps
Interventions
Biopsy Procedure, Biospecimen Collection, Colonoscopy, Dordaviprone Hydrochloride, Questionnaire Administration, Sigmoidoscopy
Procedure · Drug · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
5
States / cities
Ann Arbor, Michigan • St Louis, Missouri • Cleveland, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 1, 2026, 10:04 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Prospective, Single Blinded Study for Predicting Colon Polyp Histology With Narrow Band Imaging

NCT00613262
View directory record Official record
Conditions
Colonoscopy, Adenomatous Polyp, Neoplastic
Interventions
Narrow Band Imaging
Other
Lead sponsor
Midwest Biomedical Research
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 8, 2012 · Synced Sep 1, 2026, 10:04 PM EDT
Completed No phase listed Observational

Study of Gut Microbiome and Colorectal Tumors

NCT03297996
View directory record Official record
Conditions
Serrated Polyp, Hyperplastic Polyp, Sessile Serrated Adenoma, Colorectal Cancer
Interventions
Mobio PowerSoil DNA Isolation Kit
Diagnostic Test
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
540 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 28, 2017 · Synced Sep 1, 2026, 10:04 PM EDT
Recruiting Not applicable Interventional

Colonoscopy vs Stool Testing for Older Adults With Colon Polyps

NCT05612347
View directory record Official record
Conditions
Colorectal Polyp, Colorectal Neoplasms, Colorectal Adenoma, Colorectal Cancer, Digestive System Disease
Interventions
FIT, Colonoscopy
Diagnostic Test
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
65 Years to 82 Years
Enrollment
8,946 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2035
U.S. locations
20
States / cities
Birmingham, Alabama • Tucson, Arizona • San Diego, California + 17 more
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 1, 2026, 10:04 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Does the Cap Increase the Finding of Polyps When Water Exchange Colonoscopy is Used

NCT03566615
View directory record Official record
Conditions
Colonoscopy, Polyp of Colon
Interventions
CAP-straight, CAP-daisy, water
Device · Other
Lead sponsor
VA Greater Los Angeles Healthcare System
Federal
Eligibility
50 Years to 75 Years
Enrollment
1,630 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
2
States / cities
Mather, California • Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2022 · Synced Sep 1, 2026, 10:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study to Evaluate the Safety and Efficacy of the Use of ME-APDS During Colonoscopy

NCT04640792
View directory record Official record
Conditions
Screening Colonoscopy, Surveillance Colonoscopy
Interventions
Screening or Surveillance Conventionall colonoscopy
Procedure
Lead sponsor
Magentiq Eye LTD
Industry
Eligibility
18 Years to 90 Years
Enrollment
952 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
4
States / cities
Baltimore, Maryland • New York, New York • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated May 4, 2022 · Synced Sep 1, 2026, 10:04 PM EDT
Completed No phase listed Observational

Calcium/Vitamin D, Biomarkers & Colon Polyp Prevention

NCT00399607
View directory record Official record
Conditions
Colorectal Adenomatous Polyps
Interventions
Rectal biopsy during colonoscopy, Rectal biopsy at randomization, Rectal biopsy at 1 year, Rectal biopsy prior to colonoscopy, Biopsies during colonoscopy
Procedure
Lead sponsor
Emory University
Other
Eligibility
45 Years to 75 Years
Enrollment
264 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2016
U.S. locations
9
States / cities
Los Angeles, California • Denver, Colorado • Atlanta, Georgia + 6 more
Source: ClinicalTrials.gov public record
Updated Dec 7, 2016 · Synced Sep 1, 2026, 10:04 PM EDT
Completed Not applicable Interventional

Multimedia Intervention in Patients With Familial Adenomatous Polyposis (FAP)

NCT00525655
View directory record Official record
Conditions
Familial Adenomatous Polyposis, Colorectal Cancer
Interventions
Web-Based Multimedia Intervention, Questionnaire
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
13 Years to 24 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 22, 2021 · Synced Sep 1, 2026, 10:04 PM EDT
Terminated No phase listed Observational

Review of Post-Study Clinical Endoscopy Reports in Follow Up to MAY2016-07-01

NCT04674228
View directory record Official record
Conditions
Familial Adenomatous Polyposis
Interventions
Electronic Health Record Review
Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
Not listed
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
Rochester, Minnesota • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 1, 2026, 10:04 PM EDT
Completed Not applicable Interventional

Ambient Lighting During Colonoscopy and Its Effect on Adenoma Detection Rate and Eye Fatigue

NCT04441242
View directory record Official record
Conditions
Colorectal Cancer Screening, Colon Adenomatous Polyp
Interventions
Ambient lighting, Low lighting
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
1,109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Park Ridge, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Sep 1, 2026, 10:04 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Detection and Classification of Colon Polyps

NCT00825292
View directory record Official record
Conditions
Colon Polyps
Interventions
Polp removal and identification, colon polyp removal, ETMI colonoscope (ETMI scope is a FDA approved device)
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 20, 2009 · Synced Sep 1, 2026, 10:04 PM EDT
Recruiting No phase listed Observational

Gastrointestinal Biomarkers in Tissue and Biological Fluid Samples From Colorectal Cancer Patients

NCT00899626
View directory record Official record
Conditions
Colorectal Cancer, Esophageal Cancer, Gastric Cancer, Pancreatic Cancer, Precancerous Condition
Interventions
Not listed
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2045
U.S. locations
2
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Sep 1, 2026, 10:04 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Vitamin D/Calcium Polyp Prevention Study

NCT00153816
View directory record Official record
Conditions
Colorectal Cancer, Polyps, Adenomas
Interventions
Calcium Carbonate, Vitamin D3, placebo
Drug
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
45 Years to 75 Years
Enrollment
2,813 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2016
U.S. locations
10
States / cities
Los Angeles, California • Denver, Colorado • Atlanta, Georgia + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 14, 2017 · Synced Sep 1, 2026, 10:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Does Cap Assisted Colonoscopy Improve Detection of Adenomatous Polyps? (CAP Trial)

NCT01935180
View directory record Official record
Conditions
Adenomatous Polyps
Interventions
Colonoscopy Cap
Device
Lead sponsor
White River Junction Veterans Affairs Medical Center
Federal
Eligibility
50 Years to 85 Years
Enrollment
1,148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
2
States / cities
Lebanon, New Hampshire • White River Junction, Vermont
Source: ClinicalTrials.gov public record
Updated Sep 24, 2018 · Synced Sep 1, 2026, 10:04 PM EDT
Completed Not applicable Interventional

Real-time Computer-Aided Detection of Colonic Adenomas With NEC WISE VISION® Endoscopy

NCT05611151
View directory record Official record
Conditions
Colorectal Cancer, Adenoma Colon, Polyp of Colon
Interventions
Computer Aided Detection (CADe)
Diagnostic Test
Lead sponsor
NEC Corporation
Industry
Eligibility
45 Years to 75 Years
Enrollment
830 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 1, 2026, 10:04 PM EDT
Terminated Not applicable Interventional

Study of Performance of Confocal Endomicroscope With Fluorescein Imaging Agent in the Colon

NCT03220711
View directory record Official record
Conditions
Colonic Dysplasia, Adenomatous Polyps, Irritable Bowel Disease
Interventions
confocal endomicroscope, Fluorescein
Device · Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 100 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 21, 2022 · Synced Sep 1, 2026, 10:04 PM EDT
Recruiting Phase 1Phase 2 Interventional

FOG-001 in Locally Advanced or Metastatic Solid Tumors

NCT05919264
View directory record Official record
Conditions
Cancer, Colorectal Cancer, Solid Tumor, Locally Advanced Solid Tumor, Metastatic Cancer, WNT Pathway, HCC, Desmoid, Microsatellite Stable Colorectal Cancer, Metastatic Castration-resistant Prostate Cancer, Familial Adenomatous Polyposis (FAP), Endometrial Carcinoma, Prostate Cancer, Microsatellite Instability-High Colorectal Cancer, Adamantinomatous Craniopharyngioma
Interventions
FOG-001, mFOLFOX-6, Nivolumab, Trifluridine/tipiracil, Bevacizumab
Drug
Lead sponsor
Parabilis Medicines, Inc.
Industry
Eligibility
18 Years and older
Enrollment
619 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
31
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Tucson, Arizona + 25 more
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 1, 2026, 10:04 PM EDT