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ClinicalTrials.gov public records Last synced Oct 18, 2026, 12:29 AM EDT

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Showing 97–120 of 138 matching trials from the live ClinicalTrials.gov search.
Completed No phase listed Observational Accepts healthy volunteers

Plasma ctDNA in Patients Undergoing Diagnostic Colonoscopy

NCT02665299
Conditions
Colon Cancer, Colon Adenomas, Colon Polyps
Interventions
Not listed
Lead sponsor
Pathway Genomics
Industry
Eligibility
18 Years and older
Enrollment
206 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
San Diego, California
Conditions
Attenuated Familial Adenomatous Polyposis, Familial Adenomatous Polyposis
Interventions
Erlotinib, Erlotinib Hydrochloride
Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 69 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
7
States / cities
Scottsdale, Arizona • Ann Arbor, Michigan • Rochester, Minnesota + 4 more
Conditions
Colorectal Cancer, Esophageal Cancer, Gastric Cancer, Pancreatic Cancer, Precancerous Condition
Interventions
Not listed
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2045
U.S. locations
2
States / cities
Nashville, Tennessee
Conditions
Colorectal Adenomatous Polyp, Colorectal Carcinoma, Familial Adenomatous Polyposis, Multiple Adenomatous Polyps
Interventions
Biopsy Procedure, Biospecimen Collection, Colonoscopy, Dordaviprone Hydrochloride, Endoscopic Procedure, Questionnaire Administration, Sigmoidoscopy
Procedure · Drug · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
5
States / cities
Ann Arbor, Michigan • St Louis, Missouri • Cleveland, Ohio + 2 more
Conditions
Colonic Polyps
Interventions
AmplifEYE
Device
Lead sponsor
Loma Linda University
Other
Eligibility
50 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Loma Linda, California
Conditions
Colorectal Cancer, Precancerous Condition
Interventions
Vitamin E, Selenium, Vitamin E placebo, selenium placebo
Drug
Lead sponsor
SWOG Cancer Research Network
Network
Eligibility
50 Years to 120 Years · Male only
Enrollment
8,094 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2018
U.S. locations
1
States / cities
Tucson, Arizona
Conditions
Familial Adenomatous Polyposis
Interventions
Exercise Therapy
Procedure
Lead sponsor
University of Michigan Rogel Cancer Center
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Ann Arbor, Michigan • Cleveland, Ohio
Conditions
Metastatic Colorectal Carcinoma (mCRC), Colorectal Cancer (CRC), Adenomatous Polyposis Coli (APC) Gene Mutation, Catenin Beta-1 (CTNNB1) Gene Mutation
Interventions
Tegavivint
Drug
Lead sponsor
HonorHealth Research Institute
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Scottsdale, Arizona
Completed Not applicable Interventional Results available

EndoRotor® Endoscopic Mucosal Resection System for the Colon

NCT04203667
Conditions
Polyp of Colon, Endoscopic Mucosal Resection, Recurrent Colon Adenoma
Interventions
EndoRotor Resection
Device
Lead sponsor
Interscope, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Danville, Pennsylvania
Conditions
Colorectal Adenoma, Colorectal Polyp, Colorectal Adenocarcinoma, Colorectal SSA
Interventions
Ultivision Artificial Intelligence Software, No Artificial Intelligence Software enhancement
Device
Lead sponsor
Docbot, Inc.
Industry
Eligibility
45 Years to 75 Years
Enrollment
978 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
9
States / cities
Birmingham, Alabama • San Diego, California • Kansas City, Kansas + 6 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Post-resection Treatment of Large Colon Polyps

NCT03654209
Conditions
Recurrence
Interventions
Argon Plasma Coagulation, Snare Tip Soft Coagulation
Device
Lead sponsor
Indiana University
Other
Eligibility
25 Years and older
Enrollment
384 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
10
States / cities
Washington D.C., District of Columbia • Orlando, Florida • Indianapolis, Indiana + 5 more
Conditions
Familial Adenomatous Polyposis
Interventions
Personalized surveillance and intervention protocol
Procedure
Lead sponsor
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Colorectal Cancer and Pre-Cancerous Adenoma Non-Invasive Detection Test Study

NCT04739722
Conditions
Colorectal Cancer, Advanced Adenocarcinoma, Serrated Polyp
Interventions
ColoSense
Diagnostic Test
Lead sponsor
Geneoscopy, Inc.
Industry
Eligibility
45 Years and older
Enrollment
14,263 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
St Louis, Missouri • Austin, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Endocuff Vision Colonoscopy vs. AmplifEYE Colonoscopy

NCT03560128
Conditions
Colorectal Adenoma, Colorectal Polyp, Colorectal Cancer
Interventions
Endocuff Vision device, AmplifEYE device
Device
Lead sponsor
Indiana University
Other
Eligibility
40 Years and older
Enrollment
634 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Indianapolis, Indiana
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

Selenium for Prevention of Adenomatous Colorectal Polyps

NCT00078897
Conditions
Colorectal Cancer, Adenomatous Colorectal Polyps, Precancerous Condition
Interventions
Selenium
Drug
Lead sponsor
University of Arizona
Other
Eligibility
40 Years to 80 Years
Enrollment
1,621 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2018
U.S. locations
7
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Tucson, Arizona + 3 more
Completed Not applicable Interventional Accepts healthy volunteers

Practice-Based Learning to Predict Polyp Histology at Colonoscopy

NCT01638091
Conditions
Colonic Polyps, Adenomatous Polyps
Interventions
Ex vivo module, In vivo practice-base learning phase
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
Not listed
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2011
U.S. locations
2
States / cities
Stanford, California • Ann Arbor, Michigan
Completed Not applicable Interventional Accepts healthy volunteers Results available

Polyp Detection With the EndoRings™: A Randomized Tandem Colonoscopy Study

NCT01955122
Conditions
Colon Cancer
Interventions
Tandem Colonoscopy
Device
Lead sponsor
EndoAid
Industry
Eligibility
40 Years to 75 Years
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Screening Colonoscopy, Surveillance Colonoscopy
Interventions
Screening or Surveillance Conventionall colonoscopy
Procedure
Lead sponsor
Magentiq Eye LTD
Industry
Eligibility
18 Years to 90 Years
Enrollment
952 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
4
States / cities
Baltimore, Maryland • New York, New York • Cleveland, Ohio + 1 more
Conditions
Rectal Cancer, Ulcerative Colitis, Familial Adenomatous Polyposis, Diverticulitis
Interventions
GORE SEAMGUARD® Bioabsorbable Staple Line Reinforcement, Staple line without reinforcement
Device · Procedure
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
258 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
16
States / cities
Mobile, Alabama • Los Angeles, California • Weston, Florida + 12 more
Completed Phase 1 Interventional Accepts healthy volunteers

Effect of Folate on Colon and Blood Cells

NCT00220012
Conditions
Subjects Will Have a Pre-cancerous Colorectal Polyp, Family Member Has History of Colorectal Adenoma of Adenocarcinoma
Interventions
Folate depletion and supplementation
Procedure
Lead sponsor
Rockefeller University
Other
Eligibility
40 Years to 72 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Third Eye Retroscope Randomized Clinical Evaluation

NCT01044732
Conditions
Colorectal Neoplasms
Interventions
Third Eye Retroscope
Device
Lead sponsor
Avantis Medical Systems
Industry
Eligibility
Not listed
Enrollment
448 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
5
States / cities
Baltimore, Maryland • Kansas City, Missouri • Lebanon, New Hampshire + 2 more
Conditions
Familial Adenomatous Polyposis (FAP)
Interventions
eRapa (encapsulated rapamycin), Placebo
Drug
Lead sponsor
Rapamycin Holdings Inc.
Industry
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
18
States / cities
Arcadia, California • New Haven, Connecticut • Washington D.C., District of Columbia + 14 more
Recruiting No phase listed Observational Accepts healthy volunteers

Integrated Cancer Repository for Cancer Research

NCT02012699
Conditions
Pancreatic Cancer, Thyroid Cancer, Lung Cancer, Esophageal Cancer, Thymus Cancer, Colon Cancer, Rectal Cancer, Gastrointestinal Stromal Tumors, Anal Cancer, Bile Duct Cancer, Duodenal Cancer, Gallbladder Cancer, Gastric Cancer, Liver Cancer, Small Intestine Cancer, Peritoneal Surface Malignancies, Familial Adenomatous Polyposis, Lynch Syndrome, Bladder Cancer, Kidney Cancer, Penile Cancer, Prostate Cancer, Testicular Cancer, Ureter Cancer, Urethral Cancer, Hypopharyngeal Cancer, Laryngeal Cancer, Lip Cancer, Oral Cavity Cancer, Nasopharyngeal Cancer, Oropharyngeal Cancer, Paranasal Sinus Cancer, Nasal Cavity Cancer, Salivary Gland Cancer, Skin Cancer, Central Nervous System Tumor, Central Nervous System Cancer, Mesothelioma, Breast Cancer, Leukemia, Melanoma, Sarcoma, Unknown Primary Tumor, Multiple Myeloma, Ovarian Cancer, Endometrial Cancer, Vaginal Cancer, Neuroendocrine Tumors, Plasma Cell Dyscrasia, Healthy Control
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 110 Years
Enrollment
999,999 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2099
U.S. locations
42
States / cities
Greenwood Village, Colorado • Manchester, Connecticut • Daytona Beach, Florida + 34 more
Completed Phase 2Phase 3 Interventional Results available

Vitamin D/Calcium Polyp Prevention Study

NCT00153816
Conditions
Colorectal Cancer, Polyps, Adenomas
Interventions
Calcium Carbonate, Vitamin D3, placebo
Drug
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
45 Years to 75 Years
Enrollment
2,813 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2016
U.S. locations
10
States / cities
Los Angeles, California • Denver, Colorado • Atlanta, Georgia + 7 more