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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Adolescent Alcohol Use Clear all
Recruiting Not applicable Interventional

Technology Interventions for Youth Alcohol Use

NCT05988931
View directory record Official record
Conditions
Alcohol Drinking
Interventions
Web Program + App, Web Program + App + Text Messages
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
12 Years to 19 Years
Enrollment
1,400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Jul 22, 2026, 5:55 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Journey of Transformation Curriculum for Native American Adolescents

NCT05274217
View directory record Official record
Conditions
Alcohol Use, Tobacco Use, Substance Use, Sexual Health
Interventions
Journey of Transformation-Native Youth Health Leadership Program curriculum
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
13 Years to 16 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 3, 2023 · Synced Jul 22, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mindfulness-Based College: Stage 1

NCT03124446
View directory record Official record
Conditions
Diet Habit, Physical Activity, Sleep, Loneliness, Emotional Regulation, Alcohol Consumption, Youth, Stress, Psychological
Interventions
Mindfulness-Based College, Enhanced Usual Care Control
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 28 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 11, 2019 · Synced Jul 22, 2026, 5:55 AM EDT
Completed Not applicable Interventional Results available

Screening and Brief Advice to Reduce Teen Substance Use

NCT00227877
View directory record Official record
Conditions
Substance Related Disorders
Interventions
cSBA - New England, USA, cSBA - Prague, CZR
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 18 Years
Enrollment
2,695 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
5
States / cities
Boston, Massachusetts • Cambridge, Massachusetts • Worcester, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2019 · Synced Jul 22, 2026, 5:55 AM EDT
Completed Phase 2 Interventional

Brief Voluntary Alcohol and Drug Intervention for Middle School Youth

NCT01081119
View directory record Official record
Conditions
Alcohol Drinking, Cigarette Smoking, Marijuana Smoking
Interventions
Project CHOICE
Behavioral
Lead sponsor
RAND
Other
Eligibility
11 Years to 15 Years
Enrollment
6,455 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2014 · Synced Jul 22, 2026, 5:55 AM EDT
Withdrawn Not applicable Interventional

Reducing Problematic Substance Use in Youth With Chronic Medical Conditions

NCT01709201
View directory record Official record
Conditions
Alcohol Abuse, Drug Abuse
Interventions
Brief Intervention
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
14 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 20, 2017 · Synced Jul 22, 2026, 5:55 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Parent Intervention to Reduce College Student Drinking and Consequences

NCT04247191
View directory record Official record
Conditions
Underage Drinking, Driving Under the Influence, Drinking, Teen, Drinking, College
Interventions
P-Chat+, PBI
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 19 Years
Enrollment
2,061 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Jul 22, 2026, 5:55 AM EDT
Completed Phase 1Phase 2 Interventional

Reducing Health Risk Behavior and Improving Health in Adolescents With Depression

NCT00461539
View directory record Official record
Conditions
Depression, Adolescent Health
Interventions
Treatment as usual, Behavioral health intervention
Other · Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
13 Years to 18 Years
Enrollment
217 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 2, 2022 · Synced Jul 22, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Motivation and Skills for Delta-9-tetrahydrocannabinol/Ethanol (THC/ETOH+) Teens in Jail

NCT00506753
View directory record Official record
Conditions
Alcohol Drinking, Marijuana Smoking
Interventions
MI/CBT, RT/SU
Behavioral
Lead sponsor
University of Rhode Island
Other
Eligibility
14 Years to 19 Years
Enrollment
205 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2011
U.S. locations
1
States / cities
Cranston, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 14, 2019 · Synced Jul 22, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Culturally Enhancing a Motivational Interviewing Intervention For Latinx Adolescents

NCT03947177
View directory record Official record
Conditions
Underage Alcohol Use, Smoking, Non-Tobacco Products
Interventions
GMIT+
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
10 Years to 16 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 29, 2022 · Synced Jul 22, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Respecting the Circle of Life on Pregnancy Prevention Outcomes Among American Indian Adolescents

NCT02904629
View directory record Official record
Conditions
Sex, Unprotected Sex, Contraception, Alcohol Use, Drug Use, Pregnancy
Interventions
Respecting the Circle of Life (RCL), Control Program
Behavioral · Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
11 Years and older
Enrollment
1,072 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Whiteriver, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 18, 2022 · Synced Jul 22, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adolescent Safer Sex Social Network Intervention

NCT00107562
View directory record Official record
Conditions
Sexual Behavior, Alcohol Drinking, Marijuana Smoking
Interventions
Adolescent Safer Sex Social Network Intervention
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
16 Years to 19 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
2
States / cities
Tampa, Florida • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 27, 2017 · Synced Jul 22, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

REAL Parenting Alcohol and Substance Use App

NCT03932097
View directory record Official record
Conditions
Underage Drinking, Alcohol Use, Underage
Interventions
REAL Parenting, Active Control Materials
Behavioral · Other
Lead sponsor
Real Prevention, LLC
Industry
Eligibility
15 Years to 18 Years
Enrollment
306 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Clifton, New Jersey
Source: ClinicalTrials.gov public record
Updated May 24, 2023 · Synced Jul 22, 2026, 5:55 AM EDT
Completed Not applicable Interventional

SafERteens M-Coach

NCT03344666
View directory record Official record
Conditions
Alcohol Drinking, Violence
Interventions
Step 1 Treatment BI+HC, Step 1 Treatment BI+TM, Step 2 Treatment Responders, Step 2 Treatment Non-Responders
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
14 Years to 20 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
4
States / cities
Ann Arbor, Michigan • Detroit, Michigan • Flint, Michigan + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 4, 2024 · Synced Jul 22, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project e-PBI+ - Parent Intervention to Reduce College Student Drinking and Cannabis Use

NCT05345951
View directory record Official record
Conditions
Underage Drinking, Cannabis Use, Drinking, Teen, Drinking, College, College Drinking, Teen Drinking
Interventions
e-PBI
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 19 Years
Enrollment
1,980 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Jul 22, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family Intervention for Teen Drinking in the ER

NCT01229748
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Standard Care, Multidimensional Family Therapy, Family Motivational Interviewing Intervention
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
12 Years to 18 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
3
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 30, 2015 · Synced Jul 22, 2026, 5:55 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effectiveness of Brief Intervention in Primary Care for Diverse Young People (Chat)

NCT06699251
View directory record Official record
Conditions
Adolescent Drinking, Cannabis Use
Interventions
Chat, Enhanced Usual Care
Behavioral
Lead sponsor
RAND
Other
Eligibility
12 Years to 19 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
2
States / cities
Commerce, California • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Jul 22, 2026, 5:55 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

ChangeGradients: Promoting Adolescent Health Behavior Change

NCT04110756
View directory record Official record
Conditions
Alcohol Drinking, Self Efficacy, Adolescent Behavior, Risk-Taking, Cancer
Interventions
ChangeGradients
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
15 Years to 17 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Jul 22, 2026, 5:55 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Norms Re-education to Promote Engagement in Parent-based Interventions

NCT06871982
View directory record Official record
Conditions
Underage Drinking
Interventions
PNF+ PBI, SNMC+ PBI, PH+ PBI
Behavioral
Lead sponsor
Loyola Marymount University
Other
Eligibility
17 Years to 20 Years
Enrollment
2,040 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Jul 22, 2026, 5:55 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Game-Based Intervention to Reduce Alcohol Use Among Youth

NCT07463118
View directory record Official record
Conditions
Alcohol Problem
Interventions
Food4Thought, Singularities
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
14 Years to 18 Years
Enrollment
1,992 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Jul 22, 2026, 5:55 AM EDT
Recruiting Not applicable Interventional

Centralized Virtual SBIRT for Pediatric Primary Care

NCT06486688
View directory record Official record
Conditions
Adolescent Alcohol Use, Mental Health Issue, Alcohol Related Disorders, Adolescents
Interventions
Centralized Virtual SBIRT
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
12 Years to 17 Years
Enrollment
22,320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Jul 7, 2024 · Synced Jul 22, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Experimental Test of Facebook Social Drinking Norms on Adolescent Alcohol Use

NCT03159286
View directory record Official record
Conditions
Feedback, Psychological, Underage Alcohol Use, Risk-Taking
Interventions
Abstainer, Abstainer + User, Control
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
15 Years to 20 Years
Enrollment
306 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 20, 2019 · Synced Jul 22, 2026, 5:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

SBIRT Implementation for Adolescents in Urban Federally Qualified Health Centers

NCT01829308
View directory record Official record
Conditions
Alcohol-induced Disorders, Drug Users, Tobacco Use Disorder
Interventions
The brief interventions are delivered by behavioral health counselors (Specialist), The brief interventions are delivered by the primary care provider (Generalist)
Behavioral
Lead sponsor
Friends Research Institute, Inc.
Other
Eligibility
18 Years to 99 Years
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 13, 2018 · Synced Jul 22, 2026, 5:55 AM EDT
Completed Phase 3 Interventional

EEG/Event-related Brain Potential Risk Markers as Predictors and Outcomes of SUD Treatment in Adolescents

NCT02016378
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Bias retraining, Sham retraining
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
14 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 12, 2022 · Synced Jul 22, 2026, 5:55 AM EDT