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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Adolescent Substance Abuse Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Family-Based Drug Services for Young Disaster Victims

NCT01859000
View directory record Official record
Conditions
Substance Abuse, Families, Trauma
Interventions
Multidimensional Family Therapy, Group CBT
Other
Lead sponsor
University of Miami
Other
Eligibility
13 Years to 17 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
2
States / cities
Miami, Florida • Luling, Louisiana
Source: ClinicalTrials.gov public record
Updated May 20, 2013 · Synced Jun 11, 2026, 1:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family Intervention for Teen Drinking in the ER

NCT01229748
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Standard Care, Multidimensional Family Therapy, Family Motivational Interviewing Intervention
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
12 Years to 18 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
3
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 30, 2015 · Synced Jun 11, 2026, 1:37 AM EDT
Completed Not applicable Interventional Results available

Community Trial in the Cherokee Nation

NCT04839978
View directory record Official record
Conditions
Opioid Abuse
Interventions
Connect Program, Communities Mobilizing for Change and Action (CMCA)
Behavioral
Lead sponsor
Emory University
Other
Eligibility
15 Years to 17 Years
Enrollment
919 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Tahlequah, Oklahoma
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Jun 11, 2026, 1:37 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Comparative Effectiveness of Web-based Versus Traditional Adolescent HIV Prevention

NCT01142882
View directory record Official record
Conditions
HIV Infections, Hepatitis, Sexually Transmitted Infections
Interventions
Traditional Prevention, Web-based Prevention
Behavioral
Lead sponsor
National Development and Research Institutes, Inc.
Other
Eligibility
12 Years to 18 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
3
States / cities
Brooklyn, New York • Jamaica, New York • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jul 19, 2011 · Synced Jun 11, 2026, 1:37 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Brief Intervention for Families of Teens Treated in the Emergency Department for an Alcohol-Related Event

NCT00247221
View directory record Official record
Conditions
Alcohol Abuse
Interventions
MI/Family Check-up, MI only
Behavioral
Lead sponsor
Brown University
Other
Eligibility
13 Years to 17 Years
Enrollment
208 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2008
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 30, 2012 · Synced Jun 11, 2026, 1:37 AM EDT
Completed Phase 2 Interventional

Medical Office Intervention for Adolescent Drug Use

NCT00229983
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Motivational Enhancement Therapy
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 21 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 6, 2016 · Synced Jun 11, 2026, 1:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Computerized Alcohol Screening for Children and Adolescents (cASCA) in Primary Care

NCT02233946
View directory record Official record
Conditions
Prevention Harmful Effects
Interventions
computer-facilitated brief intervention
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
9 Years to 18 Years
Enrollment
871 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
5
States / cities
Boston, Massachusetts • East Boston, Massachusetts • Lexington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 10, 2021 · Synced Jun 11, 2026, 1:37 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Adolescent Substance Abuse: Progressive Treatment

NCT00680576
View directory record Official record
Conditions
Substance Abuse
Interventions
CBT, Cognitive Behavioral Therapy, FFT, Family Functional Therapy
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
13 Years to 18 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Oct 9, 2014 · Synced Jun 11, 2026, 1:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Individual vs. Group Community Reinforcement Training to Help Parents of Substance-using Treatment-refusing Youth

NCT01829789
View directory record Official record
Conditions
Substance Use Disorders, Treatment Refusal
Interventions
Group Community Reinforcement Training for Parents, Individual Community Reinforcement Training for Parents
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
Not listed
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 29, 2016 · Synced Jun 11, 2026, 1:37 AM EDT
Completed Phase 3 Interventional

Adolescent Outpatient and Continuing Care Study

NCT01381133
View directory record Official record
Conditions
Substance Abuse, Substance Dependence
Interventions
Chestnut Bloomington Outpatient (CBOP), Motivational Enhancement Therapy/Cognitive Behavior Treatment (MET/CBT 7), Assertive Continuing Care (ACC)
Behavioral
Lead sponsor
Chestnut Health Systems
Other
Eligibility
12 Years to 18 Years
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Bloomington, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 13, 2013 · Synced Jun 11, 2026, 1:37 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Prenatal Drug Exposure: Effects on the Adolescent Brain and Behavior Development

NCT01020669
View directory record Official record
Conditions
Drug Abuse, Prenatal Drug Exposure
Interventions
Not listed
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
13 Years to 17 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Catonsville, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jun 11, 2026, 1:37 AM EDT
Completed Not applicable Interventional

Motivational Interviews for Incarcerated Teens - 1

NCT00227916
View directory record Official record
Conditions
Alcoholic Intoxication, Marijuana Abuse
Interventions
Behavior Therapy
Behavioral
Lead sponsor
Brown University
Other
Eligibility
14 Years to 19 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2004
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 24, 2014 · Synced Jun 11, 2026, 1:37 AM EDT
Completed Phase 1 Interventional

Family-Based Protocol for Medication Integration in Treatment of Comorbid ASU/ADHD in Routine Care

NCT01539941
View directory record Official record
Conditions
Adolescent Substance Abuse, Attention Deficit Hyperactivity Disorder
Interventions
Medication integration protocol
Behavioral
Lead sponsor
The National Center on Addiction and Substance Abuse at Columbia University
Other
Eligibility
13 Years to 17 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 3, 2015 · Synced Jun 11, 2026, 1:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A High School Program for Preventing Prescription Drug Misuse

NCT03219190
View directory record Official record
Conditions
Prescription Drug Abuse, Substance Abuse, Substance Use (Drugs, Alcohol)
Interventions
LST High School Hybrid
Behavioral
Lead sponsor
National Health Promotion Associates, Inc.
Industry
Eligibility
14 Years to 18 Years
Enrollment
1,804 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Jun 11, 2026, 1:37 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Educational Intervention for Optimizing Adolescent Mental Health Screening and Treatment in Pediatric Residency

NCT00768352
View directory record Official record
Conditions
Mental Health
Interventions
Educational intervention
Other
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 7, 2008 · Synced Jun 11, 2026, 1:37 AM EDT
Withdrawn Not applicable Interventional

Pilot Test of Computerized MET to Reduce Adolescent Alcohol Use

NCT01796158
View directory record Official record
Conditions
Alcohol Abuse
Interventions
cASBI+cMET, cASBI
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 6, 2016 · Synced Jun 11, 2026, 1:37 AM EDT
Completed Not applicable Interventional

Cognitive Skills Training for Homeless Youth

NCT01815398
View directory record Official record
Conditions
Affective Disorders, Anxiety Disorders, Attention Deficit Disorder, Substance Abuse
Interventions
Cognitive Remediation, Computer Skills Training
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 22 Years
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 27, 2017 · Synced Jun 11, 2026, 1:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brief Youth Substance Use Intervention for Primary Care

NCT00292240
View directory record Official record
Conditions
Alcohol Consumption, Drug Abuse
Interventions
Brief motivational substance use intervention
Behavioral
Lead sponsor
RAND
Other
Eligibility
12 Years to 18 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2024 · Synced Jun 11, 2026, 1:37 AM EDT
Completed Not applicable Interventional

Sequenced vs. Integrated Delivery of Treatment for Adolescent Depression and SUD

NCT00680966
View directory record Official record
Conditions
Adolescent, Depression, Substance Use Disorders
Interventions
Adolescent Coping With Depression/Functional Family Therapy
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
13 Years to 17 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 11, 2014 · Synced Jun 11, 2026, 1:37 AM EDT
Completed Phase 1Phase 2 Interventional Results available

An Open-Label Trial of N-Acetylcysteine in Cannabis Dependent Adolescents

NCT00542750
View directory record Official record
Conditions
Cannabis Dependence
Interventions
N-Acetylcysteine
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
12 Years to 20 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 22, 2018 · Synced Jun 11, 2026, 1:37 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Parent-Adolescent Interactions and Adolescent Development

NCT01572441
View directory record Official record
Conditions
Substance Abuse
Interventions
Not listed
Lead sponsor
George Mason University
Other
Eligibility
12 Years to 14 Years
Enrollment
245 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
2
States / cities
New Haven, Connecticut • Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 6, 2019 · Synced Jun 11, 2026, 1:37 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cannabis Effects on Brain Morphology in Aging

NCT01874886
View directory record Official record
Conditions
Study Focuses on Brain Morphology and Cognition in Older Subjects
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
60 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 2, 2020 · Synced Jun 11, 2026, 1:37 AM EDT
Completed Phase 2 Interventional

Validating Interventions for Diverse Adolescents

NCT01018654
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Standard Cognitive Behavioral Treatment, Culturally Adapted Cognitive-Behavioral Treatment
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
13 Years to 18 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced Jun 11, 2026, 1:37 AM EDT
Recruiting Not applicable Interventional

Neuroimaging of Adolescent Cannabis Use Treatment

NCT07340554
View directory record Official record
Conditions
Cannabis Use, Cannabis Dependence, Cannabis Use Disorder, Cannabis Abuse, Cannabis Intoxication, Cannabis Smoking, Cannabis Withdrawal, Cannabis-Related Disorder, Cannabis Abuse, in Remission, Cannabis Abuse, Episodic Use, Marijuana, Marijuana Abuse, Marijuana Use, Marijuana Smoking, Marijuana Dependence, Marijuana User, Marijuana-Related Disorder, Marijuana Use Disorder, Addiction, Addiction, Substance, Substance Use, Substance Use Disorders, Substance Dependence, Substance Abuse, Substance Related Problem, Substance Abuse Drug Chronic
Interventions
Contingency Management, Elastic Net Regression
Behavioral · Device
Lead sponsor
Indiana University
Other
Eligibility
14 Years to 17 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Jun 11, 2026, 1:37 AM EDT