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ClinicalTrials.gov public records Last synced May 22, 2026, 5:45 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Adolescent Substance Use Clear all
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Cannabis Use
Interventions
Teen Marijuana Check Up, Treatment as Usual, Gold Standard Coaching, As Needed Coaching
Behavioral · Other
Lead sponsor
University of Washington
Other
Eligibility
14 Years and older
Enrollment
264 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 14, 2023 · Synced May 22, 2026, 5:45 AM EDT
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
HIV/AIDS, Young Adult, Mobile Health, Mental Health Issue, Substance Use
Interventions
Standard of Care, Video-counseling+app
Other · Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 29 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced May 22, 2026, 5:45 AM EDT
Completed Phase 1 Interventional
View directory record Official record
Conditions
Adolescent Substance Abuse, Attention Deficit Hyperactivity Disorder
Interventions
Medication integration protocol
Behavioral
Lead sponsor
The National Center on Addiction and Substance Abuse at Columbia University
Other
Eligibility
13 Years to 17 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 3, 2015 · Synced May 22, 2026, 5:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Smoking Status
Interventions
Control, Media Literacy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
13 Years to 18 Years
Enrollment
1,211 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
3
States / cities
McKeesport, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 25, 2017 · Synced May 22, 2026, 5:45 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Borderline Personality Disorder in Adolescence
Interventions
DBT-A
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
13 Years to 20 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced May 22, 2026, 5:45 AM EDT
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Bipolar Disorder, Alcohol Abuse
Interventions
quetiapine and placebo, Quetiapine and Topiramate
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
12 Years to 25 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated May 22, 2017 · Synced May 22, 2026, 5:45 AM EDT
Not listed Not applicable Interventional
View directory record Official record
Conditions
Substance Use Disorders, Recidivism
Interventions
Adolescent Community Reinforcement Approach, Assertive Continuing Care, Trauma Affect Regulation Guide for Education and Therapy, Motivational Interviewing, Opioid Education Workbook
Behavioral · Other
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
15 Years to 25 Years
Enrollment
215 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Olympia, Washington
Source: ClinicalTrials.gov public record
Updated Oct 26, 2022 · Synced May 22, 2026, 5:45 AM EDT
Completed Phase 1 Interventional
View directory record Official record
Conditions
Opioid Use Disorder, Opioid Dependence
Interventions
Naltrexone
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
16 Years to 25 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 30, 2018 · Synced May 22, 2026, 5:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Substance Use, Sexual Risk Behavior
Interventions
Group MI risk reduction program
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years to 24 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
2
States / cities
Hollywood, California • Venice Beach, California
Source: ClinicalTrials.gov public record
Updated Apr 18, 2016 · Synced May 22, 2026, 5:45 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Vaping, Adolescent, Electronic Cigarette Use, Nicotine, Cannabis
Interventions
Vaping Device Labeling
Other
Lead sponsor
University of Southern California
Other
Eligibility
11 Years to 19 Years
Enrollment
3,900 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced May 22, 2026, 5:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Violence, Substance Use, Criminal Behavior, Violence in Adolescence
Interventions
Remote Therapy Intervention (RTI), Artificial Intelligence Remote Therapy Intervention
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
14 Years to 24 Years
Enrollment
584 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
4
States / cities
Atlanta, Georgia • Detroit, Michigan • Flint, Michigan + 1 more
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced May 22, 2026, 5:45 AM EDT
Terminated Phase 4 Interventional Results available
View directory record Official record
Conditions
Vaping, Nicotine Dependence
Interventions
Varenicline, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 25 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 3, 2024 · Synced May 22, 2026, 5:45 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Substance-Related Disorders, Depressive Disorder, Anxiety Disorder
Interventions
OutPatient Treatment for Adolescents (OPT-A), Treatment As Usual
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
10 Years to 17 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced May 22, 2026, 5:45 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Diet Modification, Substance Use Disorders, Diabetes Mellitus Risk, Cardiovascular Risk Factor, Lifestyle Risk Reduction, Parenting
Interventions
Nutrition/substance use prevention, Substance use prevention only, Academic success program
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
12 Years and older
Enrollment
844 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 25, 2024 · Synced May 22, 2026, 5:45 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Behavior, Health
Interventions
Computer-based Intervention
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
12 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
2
States / cities
Detroit, Michigan • Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced May 22, 2026, 5:45 AM EDT
Completed Phase 1Phase 2 Interventional
View directory record Official record
Conditions
Use; Tobacco, Harmful, Alcohol Abuse, Drug Abuse
Interventions
iMET, iMET/TE
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 21 Years
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 6, 2016 · Synced May 22, 2026, 5:45 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Health Behavior, Wellness, Psychological, Substance Use
Interventions
Cue reactivity paradigm
Other
Lead sponsor
Brown University
Other
Eligibility
13 Years to 16 Years
Enrollment
224 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 1, 2025 · Synced May 22, 2026, 5:45 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Very low nicotine content cigarettes, Standard nicotine content cigarettes
Other
Lead sponsor
Brown University
Other
Eligibility
15 Years to 19 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 26, 2022 · Synced May 22, 2026, 5:45 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Nicotine Dependence, Nicotine Use Disorder
Interventions
Bupropion SR, Contingency Management, Placebo
Drug · Behavioral · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
12 Years to 21 Years
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 1, 2018 · Synced May 22, 2026, 5:45 AM EDT
Terminated Phase 3 Interventional Results available
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
Brief Early Intervention, Parent Training with Adolescent Cognitive Behavioral Therapy, Methylphenidate
Behavioral · Drug
Lead sponsor
Florida International University
Other
Eligibility
12 Years to 16 Years
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced May 22, 2026, 5:45 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Nicotine Dependence, Cigarettes, Uncomplicated
Interventions
Very Low Nicotine Content Cigarettes, Normal Nicotine Content Cigarettes
Drug
Lead sponsor
Brown University
Other
Eligibility
15 Years to 20 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 18, 2023 · Synced May 22, 2026, 5:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Substance Use, Delinquency, Risk for HIV Infection
Interventions
Multidimensional Family Therapy Cross-Systems, Enhanced Services as Usual
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
13 Years to 17 Years
Enrollment
154 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
5
States / cities
Clearwater, Florida • Largo, Florida • Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 21, 2014 · Synced May 22, 2026, 5:45 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
PTSD, Alcohol Use Disorders, Substance Use Disorders
Interventions
Risk Reduction through Family Therapy, Treatment as Usual
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
13 Years to 18 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 2, 2018 · Synced May 22, 2026, 5:45 AM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Substance Use Disorders, Risk Behavior, Psychiatric Disorders, Family Dysfunction
Interventions
Family Therapy based on Structural Family Therapy, Group Therapy, Psychoeducational Sessions, Individual Adolescent Therapy Sessions
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
14 Years to 17 Years
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Dec 15, 2015 · Synced May 22, 2026, 5:45 AM EDT