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Showing 25–46 of 22 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Adverse Childhood Experiences Clear all
Completed Not applicable Interventional Accepts healthy volunteers

ACEs Referral From PED

NCT06574633
View directory record Official record
Conditions
Adverse Childhood Experiences
Interventions
In-person therapy, Telehealth therapy
Behavioral
Lead sponsor
Emory University
Other
Eligibility
12 Years to 17 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
4
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Jun 11, 2026, 2:32 AM EDT
Completed Not applicable Interventional

Life Experiences in Adolescents and the Development of Skills

NCT04719897
View directory record Official record
Conditions
Depression in Adolescence, Adverse Childhood Experiences
Interventions
FIRST: Repairing Thoughts
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 15 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Jun 11, 2026, 2:32 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Neurobehavioral Mechanisms Linking Childhood Adversity to Increased Risk for Smoking

NCT05665465
View directory record Official record
Conditions
Adverse Childhood Experiences, Nicotine Dependence, Cigarettes
Interventions
Nicotine nasal spray 0.5 mg, Placebo
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 21 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Jun 11, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Building Resilience Program: Examining Self-Regulation, Behavior, and Resilience in Under-Resourced Preschoolers With ACEs

NCT07170605
View directory record Official record
Conditions
Preschool Age Children, Preschool Education, Adverse Childhood Experience, Mental Health, Resilience, Minority Groups
Interventions
Mental health, positive coping strategies promoting self-regulation and adaptive skills, Standard care/School Readiness Condition
Behavioral · Other
Lead sponsor
Cleveland State University
Other
Eligibility
24 Months to 66 Months
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Jun 11, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Testing a Scalable Model For ACEs-Related Care Navigation

NCT05567250
View directory record Official record
Conditions
Adverse Childhood Experiences, Child Development
Interventions
Behavioral: Telephone-based ACEs care coordination
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
Up to 11 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 13, 2024 · Synced Jun 11, 2026, 2:32 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

BLOOM: Boldly Living outdOOrs for Mental Health

NCT05973123
View directory record Official record
Conditions
Anxiety, Stress Disorder, Posttraumatic, Loneliness, Adverse Childhood Experiences
Interventions
Group Nature Outings, Family Outings
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
9 Years to 12 Years
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Aug 27, 2023 · Synced Jun 11, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Healing Experiences of Adversity Among Latinos (HEALthy4You)

NCT05676281
View directory record Official record
Conditions
Stress, Childhood Obesity
Interventions
Healthy Together (Control), Healthy Together + Promotora Support, Healthy Together + Parenting Training, Healthy Togethers + Parenting Training + Promotora support
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
5 Years to 11 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 31, 2025 · Synced Jun 11, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Today Not Tomorrow Pregnancy and Infant Support Program (TNT- PISP)

NCT04100577
View directory record Official record
Conditions
Infant Mortality, Infant Death, Racial Bias, Prenatal Stress, Prenatal Care, Maternal Child Health, Health Problems in Pregnancy, Adverse Childhood Experiences, Mental Health, Support Groups, Minority Health, Healthcare Disparities, Maternal-child Health Services, Social Determinants of Health, Trust, Physician-Patient Relations, Quality of Care
Interventions
Today Not Tomorrrow Pregnancy and Infant Support Program
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 13, 2022 · Synced Jun 11, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Randomized Controlled Trial to Improve Mother-Infant Synchrony Among Women With Childhood Adversity

NCT04818112
View directory record Official record
Conditions
Parent-Child Relations, Maternal Behavior, Infant Behavior
Interventions
ATVV, Attention control
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older · Female only
Enrollment
262 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Jun 11, 2026, 2:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Adversity, Brain and Opioid Use Study

NCT06355778
View directory record Official record
Conditions
Opioid Use Disorder, Healthy
Interventions
Magnetic Resonance Imaging (MRI), Computer Tasks
Other · Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 55 Years
Enrollment
185 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Jun 11, 2026, 2:32 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Childhood Trauma, Exercise, and Cognition

NCT05972265
View directory record Official record
Conditions
Adverse Childhood Experiences
Interventions
Moderate Intensity Exercise (one day), Placebo - Light Intensity Exercise (one day), Moderate Intensity Exercise (9 wks), Day 1 Assessments, Symptom Measures and Neuropsychological Tests, Day 36 Assessments, Day 57 Assessments, Day 78 Assessments
Behavioral · Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
40 Years to 60 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Nov 30, 2023 · Synced Jun 11, 2026, 2:32 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Calling All Dads! Evaluation of APAs ACT Program: Engaging Fathers to Prevent Adverse Childhood Experiences

NCT06075446
View directory record Official record
Conditions
Child Abuse
Interventions
ACT Raising Safe Kids
Behavioral
Lead sponsor
Georgia State University
Other
Eligibility
18 Years and older · Male only
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Jun 11, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An App-based Mindfulness Intervention for Sexual Minority Women With a History of Early Life Adversities (ELA)

NCT05201391
View directory record Official record
Conditions
Overweight and Obesity
Interventions
"Eat Right Now" (ERN) mobile application
Behavioral
Lead sponsor
Brown University
Other
Eligibility
30 Years to 55 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 7, 2022 · Synced Jun 11, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Building Wealth and Health Network: A Microfinance/TANF Demonstration Project

NCT02577705
View directory record Official record
Conditions
Hunger, Child Development, Social Isolation
Interventions
Self Empowerment Groups, Financial Empowerment, Matched Savings
Behavioral
Lead sponsor
Center for Hunger-Free Communities
Other
Eligibility
18 Years and older
Enrollment
145 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Jun 11, 2026, 2:32 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Evaluation of the Building Healthy Life Skills Program

NCT05611060
View directory record Official record
Conditions
Adverse Childhood Experiences, Housing Problems, Emotion Regulation
Interventions
Building Healthy Life Skills Program
Behavioral
Lead sponsor
University of California, Merced
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Merced, California
Source: ClinicalTrials.gov public record
Updated Nov 8, 2022 · Synced Jun 11, 2026, 2:32 AM EDT
Active, not recruiting Not applicable Interventional

Perinatal Depression and Adverse Childhood Experiences: Prevention Trial

NCT05795114
View directory record Official record
Conditions
Perinatal Depression
Interventions
Reach Out, Stand Strong, Essentials for New Mothers (ROSE) Program
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Jun 11, 2026, 2:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

ACEs, SIRT1, and Premature Vascular Aging in Humans

NCT07073352
View directory record Official record
Conditions
Adverse Childhood Experiences, Endothelial Dysfunction
Interventions
Nicotinamide Riboside, Placebo
Dietary Supplement
Lead sponsor
Nathaniel Jenkins
Other
Eligibility
18 Years to 30 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 17, 2025 · Synced Jun 11, 2026, 2:32 AM EDT
Completed Not applicable Interventional

Shaping Actions and Responses to Emotions

NCT04719949
View directory record Official record
Conditions
Depression in Adolescence, Adverse Childhood Experiences
Interventions
Behavioral Activation (BA) Therapy, Problem Solving Therapy (PST)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 15 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 9, 2023 · Synced Jun 11, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Examine the Effects of Mindfulness in Woman With a History of Child Adversity

NCT05255380
View directory record Official record
Conditions
Stress, Psychological Stress, Child Maltreatment, Depressive Symptoms, Signs and Symptoms
Interventions
Mindfulness and compassion-based practices; approximately 5-10 minutes two times/day, Mindful awareness and reporting of current thoughts and feelings, 2 times/day
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
30 Years to 50 Years · Female only
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 3, 2025 · Synced Jun 11, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Exercise on Young Adult Women With ACEs: an Integrative Pilot Study

NCT03521401
View directory record Official record
Conditions
Life Experiences
Interventions
Exercise
Behavioral
Lead sponsor
Oklahoma State University
Other
Eligibility
18 Years to 29 Years · Female only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Stillwater, Oklahoma
Source: ClinicalTrials.gov public record
Updated Mar 2, 2021 · Synced Jun 11, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CEDARS Intervention: A Coping, Emotional Development, & Stress Reduction Intervention

NCT04958694
View directory record Official record
Conditions
Adolescent Behavior, Stress Reduction, Adverse Childhood Experiences, Positive Attitude
Interventions
CEDARS
Behavioral
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
14 Years to 19 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Jun 11, 2026, 2:32 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Journey of Hope in Appalachia: Supporting Resilience in the Region's Youth

NCT04096937
View directory record Official record
Conditions
Adverse Childhood Experiences
Interventions
Focus groups
Other
Lead sponsor
Gia Mudd
Other
Eligibility
10 Years to 99 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
2
States / cities
Hazard, Kentucky • Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Nov 24, 2022 · Synced Jun 11, 2026, 2:32 AM EDT