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ClinicalTrials.gov public records Last synced Oct 2, 2026, 2:17 PM EDT

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Showing 25–48 of 49 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Adverse Childhood Experiences Clear all
Not listed Phase 2 Interventional Accepts healthy volunteers

Evaluation of the Building Healthy Life Skills Program

NCT05611060
View directory record Official record
Conditions
Adverse Childhood Experiences, Housing Problems, Emotion Regulation
Interventions
Building Healthy Life Skills Program
Behavioral
Lead sponsor
University of California, Merced
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Merced, California
Source: ClinicalTrials.gov public record
Updated Nov 9, 2022 · Synced Oct 2, 2026, 2:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Healing Experiences of Adversity Among Latinos (HEALthy4You)

NCT05676281
View directory record Official record
Conditions
Stress, Childhood Obesity
Interventions
Healthy Together (Control), Healthy Together + Promotora Support, Healthy Together + Parenting Training, Healthy Togethers + Parenting Training + Promotora support
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
5 Years to 11 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 1, 2025 · Synced Oct 2, 2026, 2:17 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

ACEs, SIRT1, and Premature Vascular Aging in Humans

NCT07073352
View directory record Official record
Conditions
Adverse Childhood Experiences, Endothelial Dysfunction
Interventions
Nicotinamide Riboside, Placebo
Dietary Supplement
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 30 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
2
States / cities
Iowa City, Iowa • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 2, 2026, 2:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Resilience Clinic Evaluation

NCT05690256
View directory record Official record
Conditions
Early Life Adversity, Caregiver Stress
Interventions
Resilience Clinic, Enhanced primary care
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
2 Years to 5 Years
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
4
States / cities
Oakland, California • San Leandro, California
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Oct 2, 2026, 2:17 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Relationship of Adverse Childhood Experiences to Overweight and Obesity

NCT00632346
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Not listed
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 23 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 10, 2008 · Synced Oct 2, 2026, 2:17 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

BLOOM: Boldly Living outdOOrs for Mental Health

NCT05973123
View directory record Official record
Conditions
Anxiety, Stress Disorder, Posttraumatic, Loneliness, Adverse Childhood Experiences
Interventions
Group Nature Outings, Family Outings
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
9 Years to 12 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 2, 2026, 2:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ACEs Referral From PED

NCT06574633
View directory record Official record
Conditions
Adverse Childhood Experiences
Interventions
In-person therapy, Telehealth therapy
Behavioral
Lead sponsor
Emory University
Other
Eligibility
12 Years to 17 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
4
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 25, 2025 · Synced Oct 2, 2026, 2:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Today Not Tomorrow Pregnancy and Infant Support Program (TNT- PISP)

NCT04100577
View directory record Official record
Conditions
Infant Mortality, Infant Death, Racial Bias, Prenatal Stress, Prenatal Care, Maternal Child Health, Health Problems in Pregnancy, Adverse Childhood Experiences, Mental Health, Support Groups, Minority Health, Healthcare Disparities, Maternal-child Health Services, Social Determinants of Health, Trust, Physician-Patient Relations, Quality of Care
Interventions
Today Not Tomorrrow Pregnancy and Infant Support Program
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 14, 2022 · Synced Oct 2, 2026, 2:17 PM EDT
Recruiting Not applicable Interventional

Early Life Exposures Among Children With Sickle Cell Disease

NCT05377372
View directory record Official record
Conditions
Sickle Cell Disease, Adverse Childhood Experiences, Breastfeeding
Interventions
Breastfeeding support group, Observation
Behavioral · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 2, 2026, 2:17 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs Studies

NCT06454344
View directory record Official record
Conditions
Adverse Childhood Experiences, Vascular Dilatation, Sleep, Sleep Disturbance, Psychosocial Stressor, Psychological Trauma, Endothelial Dysfunction, Inflammation, Oxidative Stress
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-i)
Behavioral
Lead sponsor
Nathaniel Jenkins
Other
Eligibility
18 Years to 29 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Oct 2, 2026, 2:17 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Probing the Role of Mitochondrial Oxidative Stress in Impaired Vascular Function Among Young Adults With Early Life Adversity

NCT07244809
View directory record Official record
Conditions
Adverse Childhood Experience, Endothelial Function (FMD), Endothelial Injury, Mitochondrial Function, Oxidative Stress, Psychosocial Influence on Cardiovascular Disease
Interventions
Mitoquinone mesylate (MitoQ), Placebo
Dietary Supplement
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 29 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Oct 2, 2026, 2:17 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Adversity, Brain and Opioid Use Study

NCT06355778
View directory record Official record
Conditions
Opioid Use Disorder, Healthy
Interventions
Magnetic Resonance Imaging (MRI), Computer Tasks
Other · Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 55 Years
Enrollment
185 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 2, 2026, 2:17 PM EDT
Recruiting Not applicable Interventional

Trauma-Informed Peer Aggression and Dating Violence Prevention for Preteens Receiving Intensive Mental Health Services

NCT06769282
View directory record Official record
Conditions
Aggression Childhood, Teen Dating Violence
Interventions
Experimental: Intervention (SPARE) plus Treatment as Usual, Treatment as Usual (TAU)
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
11 Years to 13 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 10, 2025 · Synced Oct 2, 2026, 2:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Testing a Scalable Model For ACEs-Related Care Navigation

NCT05567250
View directory record Official record
Conditions
Adverse Childhood Experiences, Child Development
Interventions
Behavioral: Telephone-based ACEs care coordination
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
Up to 11 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 14, 2024 · Synced Oct 2, 2026, 2:17 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Assessing the Gut Microbiome and Its Association With Pediatric Stress and Cognition

NCT06269614
View directory record Official record
Conditions
Autism Spectrum Disorder, Adverse Childhood Experiences, Stress Reaction
Interventions
Probiotic
Dietary Supplement
Lead sponsor
Nova Southeastern University
Other
Eligibility
4 Years to 95 Months
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Davie, Florida
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 2, 2026, 2:17 PM EDT
Completed Not applicable Interventional

Caregiver Adverse Childhood Experiences (ACEs) in Pediatric Primary Care

NCT05013138
View directory record Official record
Conditions
Child Development
Interventions
Training for ACEs and study procedures, Training on study procedures
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chamblee, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Oct 2, 2026, 2:17 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Telephone-Based Care Coordination for Services Addressing Childhood Adversity

NCT07686614
View directory record Official record
Conditions
Health Services, Mental Health, Well-being
Interventions
Telephone-based Screening and Care Coordination
Behavioral
Lead sponsor
Paul Chung
Other
Eligibility
Not listed
Enrollment
778 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Pasadena, California
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 2, 2026, 2:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pediatric ACEs Screening and Resiliency Study

NCT04182906
View directory record Official record
Conditions
Fibrinogen Abnormality, Telomere Length, Mean Leukocyte, Atopic, Acute Infection, Inflammatory Response, Self-regulation
Interventions
Care Coordination, Resiliency Clinic, Usual Care
Behavioral
Lead sponsor
UCSF Benioff Children's Hospital Oakland
Other
Eligibility
3 Months to 11 Years
Enrollment
555 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Apr 21, 2021 · Synced Oct 2, 2026, 2:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Examine the Effects of Mindfulness in Woman With a History of Child Adversity

NCT05255380
View directory record Official record
Conditions
Stress, Psychological Stress, Child Maltreatment, Depressive Symptoms, Signs and Symptoms
Interventions
Mindfulness and compassion-based practices; approximately 5-10 minutes two times/day, Mindful awareness and reporting of current thoughts and feelings, 2 times/day
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
30 Years to 50 Years · Female only
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 4, 2025 · Synced Oct 2, 2026, 2:17 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Cyclic vs. Constant Estradiol: Regimens' Effects on Brain Health

NCT07831499
View directory record Official record
Conditions
Menopause, Healthy Adult, Brain, Postmenopausal
Interventions
Cyclic Estradiol, Continuous Estradiol
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
38 Years to 60 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 2, 2026, 2:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Exercise on Young Adult Women With ACEs: an Integrative Pilot Study

NCT03521401
View directory record Official record
Conditions
Life Experiences
Interventions
Exercise
Behavioral
Lead sponsor
Oklahoma State University
Other
Eligibility
18 Years to 29 Years · Female only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Stillwater, Oklahoma
Source: ClinicalTrials.gov public record
Updated Mar 3, 2021 · Synced Oct 2, 2026, 2:17 PM EDT
Enrolling by invitation Not applicable Interventional

A Two-Part Intervention to Target Cardiovascular Health

NCT07673172
View directory record Official record
Conditions
Autism, Adverse Childhood Experience, Stress, Cardiovascular (CV) Risk
Interventions
Lifestyle Medicine, Cognitive Behavioral Therapy (CBT), Lifestyle Medicine with CBT Group
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
9 Years to 26 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 2, 2026, 2:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An App-based Mindfulness Intervention for Sexual Minority Women With a History of Early Life Adversities (ELA)

NCT05201391
View directory record Official record
Conditions
Overweight and Obesity
Interventions
"Eat Right Now" (ERN) mobile application
Behavioral
Lead sponsor
Brown University
Other
Eligibility
30 Years to 55 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 8, 2022 · Synced Oct 2, 2026, 2:17 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Calling All Dads! Evaluation of APAs ACT Program: Engaging Fathers to Prevent Adverse Childhood Experiences

NCT06075446
View directory record Official record
Conditions
Child Abuse
Interventions
ACT Raising Safe Kids
Behavioral
Lead sponsor
Georgia State University
Other
Eligibility
18 Years and older · Male only
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 2, 2026, 2:17 PM EDT