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ClinicalTrials.gov public records Last synced Oct 25, 2026, 2:57 AM EDT

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Showing 481–504 of 1,647 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Aging Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Effects of NAD3 Supplementation on Biomarkers of Aging

NCT04276948
View directory record Official record
Conditions
Aging
Interventions
NAD3
Dietary Supplement
Lead sponsor
The Center for Applied Health Sciences, LLC
Industry
Eligibility
40 Years to 60 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Canfield, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 14, 2022 · Synced Oct 25, 2026, 2:57 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Blackcurrants Modify Gut Microbiota and Reduce Osteoporosis and CVD Risk

NCT04431960
View directory record Official record
Conditions
Postmenopausal Osteoporosis, Gut Microbiota, Cardiovascular Diseases
Interventions
blackcurrant (BC) extract
Drug
Lead sponsor
University of Connecticut
Other
Eligibility
45 Years to 60 Years · Female only
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Oct 25, 2026, 2:57 AM EDT
Terminated Phase 1 Interventional

Effect of Increasing Testosterone on Insulin Sensitivity in Men With the Metabolic Syndrome

NCT00438321
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Zoladex, Testosterone gel, Anastrozole Pill, Placebo
Drug · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
50 Years to 75 Years · Male only
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Oct 25, 2026, 2:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Effect of Aging on Value Based Decision-making

NCT03341611
View directory record Official record
Conditions
Healthy Aging
Interventions
Neuro-imaging during behavioral decision-making task
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 22, 2019 · Synced Oct 25, 2026, 2:57 AM EDT
Completed Not applicable Interventional Results available

A Novel Neurorehabilitation Approach for Cognitive Aging With HIV

NCT02391311
View directory record Official record
Conditions
HIV, Aging
Interventions
transcranial direct current stimulation (tDCS)
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
50 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 15, 2017 · Synced Oct 25, 2026, 2:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Role of Inflammation and Aging in HIV-Associated Cardiovascular Risk

NCT01333644
View directory record Official record
Conditions
HIV Infection, Cardiovascular Disease, Inflammation
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
40 Years to 80 Years
Enrollment
270 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 2, 2015 · Synced Oct 25, 2026, 2:57 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Leveraging Social Networks to Improve Sleep and Mindfulness Among Older Adults in Residential Housing Facilities

NCT06989619
View directory record Official record
Conditions
Aging, Cognitive Impairment, Sleep
Interventions
Sleep health and mindfulness intervention
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
55 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 25, 2025 · Synced Oct 25, 2026, 2:57 AM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

A Deep Longitudinal Analysis of Next Generation Influenza Vaccines in Older Adults

NCT05518500
View directory record Official record
Conditions
Aging, Influenza Vaccine, Dendritic Cell, Vaccine Response
Interventions
Flu Vaccine (Year 1), Flu Vaccine (Year 2), Flu Vaccine (Year 3), Flu Vaccine (Year 4)
Biological
Lead sponsor
The Jackson Laboratory
Other
Eligibility
65 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 25, 2026, 2:57 AM EDT
Completed Not applicable Interventional

Macular Degeneration and Aging Study

NCT02224963
View directory record Official record
Conditions
Age-related Macular Degeneration
Interventions
Preventive Problem-Solving Training, Life and Health Review
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
60 Years and older
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2019
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Oct 25, 2026, 2:57 AM EDT
Active, not recruiting Early Phase 1 Interventional Accepts healthy volunteers

MitoQ and Exercise Effects on Vascular Health

NCT05686967
View directory record Official record
Conditions
Aging, Menopause
Interventions
MitoQ, Placebo, Aerobic exercise
Dietary Supplement · Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
50 Years to 120 Years · Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Oct 25, 2026, 2:57 AM EDT
Completed Phase 2 Interventional Results available

Depressed Mood Improvement Through Nicotine Dosing 2

NCT04433767
View directory record Official record
Conditions
Depressive Disorder
Interventions
Transdermal Nicotine patch
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
60 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 6, 2023 · Synced Oct 25, 2026, 2:57 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

AvoCog - the Effect of Daily Avocado Intake on Cognitive Function in Older Adults

NCT06137339
View directory record Official record
Conditions
Brain Aging
Interventions
Avocado Group
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
65 Years to 85 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Oct 25, 2026, 2:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

UCLA Fitness and Memory Study of Activity In Mild Cognitive Impairment (AIM)

NCT02001441
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
60 Years to 89 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 2, 2018 · Synced Oct 25, 2026, 2:57 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Secretome Treatment for Facial Rejuvenation

NCT07227883
View directory record Official record
Conditions
Facial Aging, Rejuvenation, Stem Cell, Stem Cell Banking
Interventions
Autologous Hair Follicle-Derived Secretome, Control Saline
Other
Lead sponsor
Acorn Biolabs Inc.
Industry
Eligibility
30 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Newport Beach, California
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 25, 2026, 2:57 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Digital Tools to Support Healthcare Decision Making

NCT07485725
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Project 3, Phase 2: Clinical Trial
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
60 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
3
States / cities
Tallahassee, Florida • Champaign, Illinois • New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 25, 2026, 2:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study to Identify if Chemist Confessions Retinol Cream Works to Improve the Appearance of Early Signs of Aging.

NCT05039476
View directory record Official record
Conditions
Wrinkle, Aging
Interventions
Retinol face cream, Placebo face cream
Dietary Supplement
Lead sponsor
Chemist Confessions, Inc.
Industry
Eligibility
30 Years to 50 Years · Female only
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 25, 2026, 2:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Anti-ageing Efficacy of a Cosmetic Formulation Containing NMN (2%) Versus Placebo

NCT04685096
View directory record Official record
Conditions
Wrinkle, Fatigue, Puffiness Around the Eyes
Interventions
Test product creme, Reference creme
Other
Lead sponsor
Seneque SA
Industry
Eligibility
40 Years to 65 Years · Female only
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 23, 2021 · Synced Oct 25, 2026, 2:57 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Community-Based Falls Prevention Program for Adults At-Risk for Falls

NCT05771818
View directory record Official record
Conditions
Accidental Fall, Neurologic Disorder, Old Age; Debility, Healthy Aging
Interventions
Falls Prevention Program
Other
Lead sponsor
University of St. Augustine for Health Sciences
Other
Eligibility
18 Years to 100 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 16, 2023 · Synced Oct 25, 2026, 2:57 AM EDT
Completed Not applicable Interventional

Behavioral Treatment of Insomnia in Aging

NCT00280020
View directory record Official record
Conditions
Aging, Insomnia
Interventions
Tai Chi Chih (TCC), Cognitive Behavior Therapy (CBT), Sleep Seminar (SS)
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
55 Years to 90 Years
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 11, 2012 · Synced Oct 25, 2026, 2:57 AM EDT
Not listed Not applicable Interventional

Noise-Enhanced Sensory Function in Elders at Risk for Falls

NCT00421759
View directory record Official record
Conditions
Aging, Somatosensory Deficit
Interventions
Vibrating Insoles
Device
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
70 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 14, 2009 · Synced Oct 25, 2026, 2:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

SystemCHANGE™ Intervention on Medication Adherence in Older Adults With Heart Failure

NCT03162848
View directory record Official record
Conditions
Medication Adherence, Heart Failure, Aging
Interventions
SystemCHANGE
Behavioral
Lead sponsor
University of Missouri, Kansas City
Other
Eligibility
50 Years and older
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Belleville, Illinois
Source: ClinicalTrials.gov public record
Updated May 28, 2019 · Synced Oct 25, 2026, 2:57 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

A Clinical Study to Evaluate the Efficacy of Activated Silk™ 27P-α in Subjects, Aged 35-65 Years of Age, to Improve the Signs of Aging

NCT06804759
View directory record Official record
Conditions
Skin Aging
Interventions
Investigational Facial Serum #1, Investigational Facial Serum #2, Investigational Facial Serum #3
Other
Lead sponsor
Victoria Collotta
Industry
Eligibility
35 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Needham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 3, 2025 · Synced Oct 25, 2026, 2:57 AM EDT
Completed Not applicable Interventional Results available

Guiding Aging Long-Term Opioid Therapy Users Into Safer Use Patterns

NCT05808127
View directory record Official record
Conditions
Pain, Opioid Use
Interventions
PainTracker, Current Opioid Misuse Measure
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
65 Years and older
Enrollment
286 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 25, 2026, 2:57 AM EDT
Recruiting Not applicable Interventional

Strength and Pain-Coping Through Resilience and Knowledge

NCT07228520
View directory record Official record
Conditions
Pain, Depressive Symptoms, Aging
Interventions
SPARK
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 25, 2026, 2:57 AM EDT