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ClinicalTrials.gov public records Last synced Oct 16, 2026, 5:37 PM EDT

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Showing 73–96 of 1,088 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Alcohol Addiction Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

The Network Study: Soldiers Connecting for Work and Health

NCT04463225
View directory record Official record
Conditions
Alcohol Use Disorder, Depression
Interventions
Internet-Delivered Brief Intervention
Other
Lead sponsor
Cornell University
Other
Eligibility
18 Years to 62 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated May 26, 2023 · Synced Oct 16, 2026, 5:37 PM EDT
Completed Phase 1Phase 2 Interventional

12-step Facilitation for the Dually Diagnosed

NCT00583440
View directory record Official record
Conditions
Alcoholism, Diagnosis, Dual (Psychiatry)
Interventions
12-step facilitation, Treatment as usual
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jan 30, 2013 · Synced Oct 16, 2026, 5:37 PM EDT
Completed Phase 4 Interventional Results available

Paroxetine for Comorbid Social Anxiety Disorder and Alcoholism

NCT00246441
View directory record Official record
Conditions
Social Anxiety Disorder, Social Phobia, Alcohol Use Disorder, Alcohol Abuse, Alcohol Dependence
Interventions
Paroxetine, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 27, 2018 · Synced Oct 16, 2026, 5:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Individualized Assessment and Treatment for Alcoholism II

NCT03233802
View directory record Official record
Conditions
Alcoholism
Interventions
Individualized Assess & Treatment (IATP), Packaged Cognitive-Behavioral (PCBT), Case Management (CaseM)
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
173 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 17, 2022 · Synced Oct 16, 2026, 5:37 PM EDT
Recruiting Not applicable Interventional

Non-invasive Vagal Nerve Stimulation as Novel Treatment to Improve Functional Outcomes in Veterans With Alcohol Use Disorder

NCT06399653
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Cervical transcutaneous vagus nerve stimulation (active comparator), Cervical transcutaneous vagus nerve stimulation (sham comparator)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Oct 16, 2026, 5:37 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Impact of a Brief Motivational Interview on Drinking Behaviors of At Risk Drinkers Screened in the Emergency Room

NCT00183183
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Screening and Brief Intervention
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
1,137 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
15
States / cities
Los Angeles, California • San Diego, California • Denver, Colorado + 10 more
Source: ClinicalTrials.gov public record
Updated May 24, 2010 · Synced Oct 16, 2026, 5:37 PM EDT
Terminated Early Phase 1 Interventional Accepts healthy volunteers

FAAH Availability in Psychiatric Disorders: A PET Study

NCT04404712
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Alcohol Use Disorder, Psychosis
Interventions
[11C]MK-3168
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 21, 2023 · Synced Oct 16, 2026, 5:37 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Oxytocin Treatment of Alcohol Dependence

NCT02251912
View directory record Official record
Conditions
Alcohol Dependence
Interventions
Intranasal Oxytocin, Placebo
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2017 · Synced Oct 16, 2026, 5:37 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Functional Neuroimaging of Alcoholism Vulnerability: Probing Glutamate and Reward, Using the mGluR5 Inhibitor Mavoglurant

NCT05203965
View directory record Official record
Conditions
Familial Alcoholism Vulnerability
Interventions
Mavoglurant (AFQ056), Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 45 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 16, 2026, 5:37 PM EDT
Completed Phase 3 Interventional Results available

Lemborexant Augmentation of Naltrexone for Alcohol Craving and Sleep

NCT05458609
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Lemborexant 10 mg, Naltrexone
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Oct 16, 2026, 5:37 PM EDT
Withdrawn Phase 2 Interventional

Use of Kudzu Extract in the Study of Its Ability to Reduce Alcohol Drinking in Treatment Seeking Alcohol Dependent Persons

NCT01853293
View directory record Official record
Conditions
Alcohol Abuse, Alcohol Dependence, Heavy Drinking Days
Interventions
Kudzu extract, Placebo, Medical Management
Drug · Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
21 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2014
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2015 · Synced Oct 16, 2026, 5:37 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Imaging CRF X NOP Interactions in Alcohol Use Disorder

NCT07612631
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Baseline [C-11]NOP-1A PET scan, Hydrocortisone, Post-hydrocortisone [C-11]NOP-1A PET scan
Radiation · Drug
Lead sponsor
Rajesh Narendran
Other
Eligibility
18 Years to 55 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2032
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 16, 2026, 5:37 PM EDT
Recruiting Not applicable Interventional

AAT for Alcohol Use Disorder in Veterans

NCT05372029
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Approach Avoidance Training, Sham Training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 16, 2026, 5:37 PM EDT
Withdrawn Not applicable Interventional

cSBI-M for Young Military Personnel

NCT01847300
View directory record Official record
Conditions
Alcohol Abuse, Tobacco Dependence, Substance Abuse
Interventions
cSBI-M
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
18 Years to 25 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2016 · Synced Oct 16, 2026, 5:37 PM EDT
Completed Phase 4 Interventional

Behavioral Therapy Plus Naltrexone for Alcoholism

NCT00000456
View directory record Official record
Conditions
Alcoholism, Alcohol Dependence
Interventions
naltrexone (Revia), cognitive behavior therapy, motivational enhancement therapy
Drug · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 70 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1992 – 2002
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 4, 2010 · Synced Oct 16, 2026, 5:37 PM EDT
Recruiting Phase 2 Interventional

Study of Tirzepatide for Recovery and Alcohol Use Management

NCT06727331
View directory record Official record
Conditions
Alcohol Use Disorder (AUD)
Interventions
Tirzepatide, Saline Placebo
Drug · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • Jamaica Plain, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 16, 2026, 5:37 PM EDT
Active, not recruiting Phase 2 Interventional

PsiloStudy: Psilocybin With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring PTSD & Alcohol Use Disorder (AUD)

NCT06853912
View directory record Official record
Conditions
Alcohol Use Disorder (AUD), PTSD
Interventions
Psilocybin 25 mg, Maltodextrin (Placebo)
Drug
Lead sponsor
Nathan Brashares Sackett
Other
Eligibility
21 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 16, 2026, 5:37 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Varenicline Treatment for Active Alcoholic Smokers

NCT01347112
View directory record Official record
Conditions
Smoking, Tobacco Dependence, Alcohol Dependence
Interventions
Varenicline, placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
2
States / cities
Rochester, Minnesota • La Crosse, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 5, 2018 · Synced Oct 16, 2026, 5:37 PM EDT
Completed Phase 2 Interventional

Study of Sunobinop on Craving in Alcohol Use Disorder

NCT06545929
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Sunobinop, Placebo to match sunobinop
Drug
Lead sponsor
Knoa Pharma LLC
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 16, 2026, 5:37 PM EDT
Terminated Not applicable Interventional

Assessing the Fit of Motivational Interviewing by Cultures With Adolescents

NCT01948700
View directory record Official record
Conditions
Alcoholism
Interventions
Motivational Interviewing, Education
Behavioral · Other
Lead sponsor
University of New Mexico
Other
Eligibility
13 Years to 18 Years
Enrollment
506 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Oct 16, 2026, 5:37 PM EDT
Completed Phase 2 Interventional Results available

Buproprion for Binge Drinking

NCT03169244
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Bupropion, Placebo Oral Tablet
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
21 Years to 44 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 26, 2020 · Synced Oct 16, 2026, 5:37 PM EDT
Completed Not applicable Interventional

Cognitive Processing Intervention for Trauma, HIV/STI Risks, and Substance Use Among Native Women

NCT01849029
View directory record Official record
Conditions
Post Traumatic Stress Disorders, Unsafe Sex, Substance Use Disorders
Interventions
Cognitive Processing Therapy-Cognitive
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Toppenish, Washington
Source: ClinicalTrials.gov public record
Updated Aug 22, 2017 · Synced Oct 16, 2026, 5:37 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Weaving Healthy Families Program

NCT03924167
View directory record Official record
Conditions
Alcohol Abuse, Drug Use, Violence, Domestic, Child Abuse, Diet Modification, Health Behavior, Health Knowledge, Attitudes, Practice, Relationship, Family, Relation, Parent-Child, Emotional Stress
Interventions
Weaving Healthy Families Program
Behavioral
Lead sponsor
Tulane University
Other
Eligibility
5 Years to 120 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Feb 20, 2024 · Synced Oct 16, 2026, 5:37 PM EDT
Completed Phase 2 Interventional Results available

Pregabalin as Treatment for Alcohol Use Disorder

NCT03256253
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Pregabalin
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 31, 2020 · Synced Oct 16, 2026, 5:37 PM EDT