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ClinicalTrials.gov public records Last synced Oct 21, 2026, 2:51 PM EDT

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Showing 457–480 of 1,300 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Alcohol Use Clear all
Completed Phase 2 Interventional Accepts healthy volunteers

A Media Based Motivational Intervention to Prevent Alcohol Exposed Pregnancies (AEPs)

NCT00219336
View directory record Official record
Conditions
Alcohol Consumption, Fetal Alcohol Syndrome Disorders, Students
Interventions
Self-guided Motivational Intervention, Informational Only
Behavioral
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
354 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2009
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Sep 30, 2016 · Synced Oct 21, 2026, 2:51 PM EDT
Completed Not applicable Interventional

Internet-based Video-conferencing to Address Alcohol Use and Pain: a Pilot Trial

NCT04441593
View directory record Official record
Conditions
Alcohol Drinking and Chronic Pain Intervention, Control Condition
Interventions
Motivational and Cognitive-Behavioral Management for Alcohol and Pain (MCBMAP), Treatment as Usual
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 13, 2024 · Synced Oct 21, 2026, 2:51 PM EDT
Terminated Phase 2 Interventional

A Study to Investigate the Safety and Efficacy of TMP-301 Compared to Placebo in Adult Patients With Alcohol Use Disorder

NCT06648655
View directory record Official record
Conditions
Alcohol Use Disorder (AUD)
Interventions
TMP-301, Placebo
Drug
Lead sponsor
Tempero Bio, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
14
States / cities
Scottsdale, Arizona • New Haven, Connecticut • Hollywood, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 21, 2026, 2:51 PM EDT
Completed Not applicable Interventional

Testing A Couple-based Program for Alcohol Risk Reduction in the National Guard

NCT03589508
View directory record Official record
Conditions
Alcohol; Harmful Use
Interventions
In-person sessions: ABCP_P, Video conference sessions: ABCP_T
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 23, 2019 · Synced Oct 21, 2026, 2:51 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

The ICEC Cluster Trial: Integrated Community Engagement Collaborative for Youth Substance Use Prevention in Rural America

NCT07843576
View directory record Official record
Conditions
Substance Use (Drugs, Alcohol), Tobacco Use, Adolescent Substance Use
Interventions
Integrated Community Engagement Collaborative, School-Based Data Collection and Reporting without Network Coordinator Support
Other
Lead sponsor
West Virginia University
Other
Eligibility
10 Years and older
Enrollment
25,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 21, 2026, 2:51 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Implementation Facilitation Pilot for Alcohol Use Disorder (AUD) in Alcohol-associated Liver Disease (ALD)

NCT07525258
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol-associated Liver Disease
Interventions
Implementation Intervention
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 21, 2026, 2:51 PM EDT
Recruiting Not applicable Interventional

The Less is More Study

NCT05153811
View directory record Official record
Conditions
Alcohol Use
Interventions
Counseling, mHealth
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
35 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Coral Gables, Florida • Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 31, 2025 · Synced Oct 21, 2026, 2:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Computer-Delivered PFI for Anxiety Sensitivity/Alcohol Intervention for Hazardous Drinkers With Elevated Anxiety Sensitivity

NCT03917875
View directory record Official record
Conditions
Alcohol Drinking, Anxiety, Coping Behavior
Interventions
Personalized feedback intervention
Behavioral
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 25, 2020 · Synced Oct 21, 2026, 2:51 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

The Effects of Topiramate on Alcohol Use in Alcohol Dependent Subjects

NCT00329407
View directory record Official record
Conditions
Alcoholism
Interventions
Topiramate (Topamax)
Drug
Lead sponsor
Boston University
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 8, 2010 · Synced Oct 21, 2026, 2:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Teen Connection Project for Trans and Gender Minority Youth

NCT06587139
View directory record Official record
Conditions
Recreational Drug Use, Sexual Violence, Victimisation, Depressive Symptoms, Anxiety, Suicidal Ideation, Risk-Taking, Alcohol Drinking
Interventions
Teen Connection Project (TCP)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
14 Years and older
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 21, 2026, 2:51 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Glutamatergic Modulation of Disordered Alcohol Use

NCT02539511
View directory record Official record
Conditions
Alcohol Dependence
Interventions
CI-581a, CI-581b, Motivational Enhancement Therapy (MET)
Drug · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 69 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 11, 2020 · Synced Oct 21, 2026, 2:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Development and Pilot Testing of a Multimodal Web-based Program to Address Heavy Drinking During Smoking Cessation

NCT03068611
View directory record Official record
Conditions
Smoking Cessation, Alcohol Drinking
Interventions
Standard Web-based Smoking Cessation, Alcohol-focused Web-Based Smoking Cessation
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 7, 2019 · Synced Oct 21, 2026, 2:51 PM EDT
Recruiting Not applicable Interventional

TMS to Improve Recovery Outcomes Among Patients With Opioid Use Disorder (OUD) and Alcohol Use Disorder (AUD)

NCT07171359
View directory record Official record
Conditions
Alcohol Use Disorder, Opioid Use Disorder
Interventions
TMS Low-Dose, TMS High-Dose
Device
Lead sponsor
Washington State University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 21, 2026, 2:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Enhancing Housing First Programs With a Social Network Substance Use Intervention

NCT02140359
View directory record Official record
Conditions
Alcohol Drinking, Drug Abuse, HIV
Interventions
Motivational Network Interview
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
2
States / cities
Los Angeles, California • Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Nov 24, 2017 · Synced Oct 21, 2026, 2:51 PM EDT
Completed Not applicable Interventional

Affective Modulation of Positivity for Alcohol Use Disorder

NCT04278365
View directory record Official record
Conditions
Anxiety, Depression, Alcohol Use Disorder
Interventions
Positive affect training
Behavioral
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 55 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Sep 1, 2020 · Synced Oct 21, 2026, 2:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Treatment Parameters for the Empower Neuromodulation System (ENS)

NCT03807544
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
TENS
Device
Lead sponsor
Theranova, L.L.C.
Industry
Eligibility
21 Years to 75 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Oct 21, 2026, 2:51 PM EDT
Completed Not applicable Interventional

Computer-Based Alcohol Use Disorder Recovery System

NCT01003119
View directory record Official record
Conditions
Alcohol Dependence
Interventions
Addiction CHESS
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Peoria, Illinois • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 4, 2016 · Synced Oct 21, 2026, 2:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Multi-Component Breath Alcohol Intervention

NCT06124898
View directory record Official record
Conditions
Alcohol Use, Alcohol Drinking, Drinking Behavior
Interventions
Alcohol-related mobile health technologies, Motivational interview and psychoeducation on blood/breath alcohol concentration, Lower tech facilitation
Device · Behavioral
Lead sponsor
Northeastern University
Other
Eligibility
18 Years to 25 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 21, 2026, 2:51 PM EDT
Completed Not applicable Interventional

D-Cycloserine to Enhance Extinction to Alcohol Cues

NCT01362309
View directory record Official record
Conditions
Alcohol Use Disorders.
Interventions
d-cycloserine.
Drug
Lead sponsor
University of Georgia
Other
Eligibility
21 Years to 65 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 19, 2014 · Synced Oct 21, 2026, 2:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Strategies: Motivational Interviewing/Psychoeducation

NCT03458299
View directory record Official record
Conditions
Alcohol Use, Underage, Substance Use, Underage Drinking
Interventions
Motivational Interviewing, Psychoeducation
Behavioral
Lead sponsor
Pacific Institute for Research and Evaluation
Other
Eligibility
13 Years to 20 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Valley Center, California
Source: ClinicalTrials.gov public record
Updated Mar 17, 2022 · Synced Oct 21, 2026, 2:51 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Alcohol Misuse, Gut Microbial Dysbiosis and PrEP Care Continuum: Application and Efficacy of SBIRT Intervention

NCT06005298
View directory record Official record
Conditions
Alcohol Use Disorder, Risk Behavior, Health, Dysbiosis, HIV Infections
Interventions
Screening, Brief Intervention, Referral to Treatment (SBIRT)
Behavioral
Lead sponsor
Shirish S Barve
Other
Eligibility
18 Years to 85 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 22, 2024 · Synced Oct 21, 2026, 2:51 PM EDT
Completed Phase 2 Interventional

Alcohol Use Disorders (AUDs) and Post-traumatic Stress Disorder (PTSD) Treatment for Victims of Partner Violence

NCT00607412
View directory record Official record
Conditions
PTSD, Substance Use Disorders
Interventions
Integrated psychotherapy for PTSD and substance use, 12-step based supportive therapy
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 11, 2011 · Synced Oct 21, 2026, 2:51 PM EDT
Recruiting Phase 2 Interventional

Donepezil and Cognitive Training for Alcohol Use Disorder (AUD)

NCT05042102
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Donepezil + Cognitive remediation therapy (CRT), Donepezil + Placebo CRT, Placebo medication + Cognitive remediation therapy (CRT), Placebo medication + Placebo CRT
Combination Product
Lead sponsor
VA Connecticut Healthcare System
Federal
Eligibility
18 Years to 80 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 21, 2026, 2:51 PM EDT
Suspended Phase 2Phase 3 Interventional Accepts healthy volunteers

CBD Oil for Reducing Emotional Impact of COVID-19

NCT04603781
View directory record Official record
Conditions
Anxiety Depression, Alcohol Abuse, Substance Abuse, Anger, Sleep Disturbance, Stress Reaction
Interventions
CBD Isolate, Full Spectrum CBD Oil, Broad-Spectrum CBD Oil, Placebo Oil
Dietary Supplement
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 70 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Nov 22, 2023 · Synced Oct 21, 2026, 2:51 PM EDT