Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 21, 2026, 8:09 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Cognitive Change, Processing, Visual Spatial, Inhibition (Psychology), Working Memory
Interventions
HUBOD, Active Comparator, Control Condition
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 45 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Urbana, Illinois
Conditions
Aging, Cognitive Change, Neurocognitive Disorders, Mild
Interventions
Contingent rtfMRI neurofeedback training, Non-contingent/sham rtfMRI neurofeedback training
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 100 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Completed No phase listed Observational Accepts healthy volunteers

Hormones and Cognition in the Menopausal Transition

NCT01429103
Conditions
Age-associated Memory Impairment, Alteration of Cognitive Function
Interventions
Not listed
Lead sponsor
University of Rochester
Other
Eligibility
40 Years to 60 Years · Female only
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Rochester, New York
Conditions
Cognitive Change
Interventions
Placebo, AmaTea Guayusa Extract, Lion's Mane
Dietary Supplement
Lead sponsor
The Center for Applied Health Sciences, LLC
Industry
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Canfield, Ohio
Conditions
Diabete Mellitus, Aging, Cognitive Change
Interventions
Sitting, Static standing, Dynamic standing
Behavioral
Lead sponsor
Science and Research Centre Koper
Other
Eligibility
65 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Avitaminosis, Delirium, Dementia, Amnestic, Cognitive Disorders
Interventions
General anesthesia with nitrous oxide, General anesthesia without nitrous oxide
Drug
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
60 Years and older
Enrollment
444 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
2
States / cities
Brooklyn, New York • New York, New York
Conditions
Cognitive Change
Interventions
N-back, Span, Multisensory
Behavioral
Lead sponsor
Northeastern University
Other
Eligibility
50 Years to 85 Years
Enrollment
313 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
2
States / cities
Irvine, California • Riverside, California
Completed Not applicable Interventional Accepts healthy volunteers

Aquatic Exercise for Cognition and Mobility in Older Adults

NCT05501249
Conditions
Aging Well, Aging Problems, Cognitive Change, Gait, Unsteady, Mobility Limitation
Interventions
Aquatic Integrated Cognitive Motor Training
Behavioral
Lead sponsor
Emily Dunlap
Other
Eligibility
65 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Austin, Texas
Completed No phase listed Observational Accepts healthy volunteers

Cannabis Observational Study on Mood, Inflammation, and Cognition

NCT03522103
Conditions
Inflammation, Inflammatory Response, Mood, Cognitive Change
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 70 Years
Enrollment
421 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Completed Not applicable Interventional Accepts healthy volunteers

The Everyday Function Intervention Trial

NCT04651582
Conditions
Cognitive Change, Cognitive Impairment, Healthy Aging, Dementia
Interventions
Cognitive Training, Cognitive Stimulating Activities
Behavioral
Lead sponsor
Clemson University
Other
Eligibility
65 Years to 90 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
State College, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers Results available

Brain and Cognitive Changes After Reasoning Training in Individuals With Mild Cognitive Impairment

NCT02596906
Conditions
Mild Cognitive Impairment
Interventions
tDCS, Sham tDCS
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
50 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Recruiting Not applicable Interventional Accepts healthy volunteers

Trout Consumption in Young Children and Families and Brain Health

NCT06721468
Conditions
Cognitive Change, Well-Being, Psychological
Interventions
Trout, Child-centered nutrition phrases, Puzzle
Other
Lead sponsor
University of Idaho
Other
Eligibility
3 Years and older
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
2
States / cities
Moscow, Idaho • Pullman, Washington
Recruiting Not applicable Interventional Accepts healthy volunteers

Cognition, Flavonoids, Exercise, Gut Microbiome

NCT06495190
Conditions
Cognitive Decline, Mild
Interventions
Blueberry, Walking, Placebo, Stretching
Dietary Supplement · Behavioral
Lead sponsor
Appalachian State University
Other
Eligibility
65 Years to 85 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Kannapolis, North Carolina
Conditions
Multiple Sclerosis
Interventions
Ocrelizumab
Drug
Lead sponsor
University at Buffalo
Other
Eligibility
18 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Buffalo, New York
Completed No phase listed Observational Accepts healthy volunteers

Early Markers of Cognitive Change and Alzheimer s Disease

NCT01867346
Conditions
Alzheimer's Disease
Interventions
Not listed
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
60 Years and older
Enrollment
2,850 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Cognitive Change
Interventions
Biomarkers of Dementia and Cognitive Decline
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
65 Years to 95 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Murray, Utah
Conditions
Traumatic Brain Injury, Word Finding Difficulty, Cognitive Symptom, Cognitive Change, Acquired Brain Injury
Interventions
Active Transcranial direct current stimulation, Sham Transcranial direct current stimulation
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Measuring Mindfulness Application

NCT04589195
Conditions
Cognitive Change
Interventions
Mindfulness Training
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 64 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Coral Gables, Florida
Completed Not applicable Interventional Accepts healthy volunteers

Peripheral Vision Training Study

NCT03141164
Conditions
Visual Impairment, Cognitive Change
Interventions
computerized training
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 89 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Stress, Mood, Cognitive Change
Interventions
Low Dose Virtiva Plus, High Dose Virtiva Plus
Dietary Supplement
Lead sponsor
Applied Science & Performance Institute
Industry
Eligibility
50 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Mental Processes, Cognitive Change, Mood Change
Interventions
Placebo, Enovita Grape Seed Extract, Mirtoselect Bilberry Extract, Virtiva Plus Ginko Biloba Extract
Dietary Supplement
Lead sponsor
Applied Science & Performance Institute
Industry
Eligibility
25 Years to 55 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Tampa, Florida
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of AMP Human Sodium Bicarbonate Lotion on Hydration

NCT04598386
Conditions
Fluid Retention, Fluid Loss, Sodium Retention, Cognitive Change, Heat Exposure, Hyperhydration, Electrolyte and Fluid Balance Conditions
Interventions
PR Lotion - AMP Human Performance, Placebo Lotion
Other
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Storrs, Connecticut
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Conversations as a Means to Delay the Onset of Alzheimer's Disease

NCT01571427
Conditions
Mild Cognitive Impairment, Cognitive Change
Interventions
Active social engagement group, Control group
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
70 Years and older
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Portland, Oregon