Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 14, 2026, 9:23 AM EDT

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Showing 1–24 of 1,988 matching trials from the live ClinicalTrials.gov search.
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Investigation of Inflammation Using [C-11]-CS1P1

NCT04517552
Conditions
Alzheimer Disease
Interventions
[11C]-CS1P1
Drug
Lead sponsor
Tammie L. S. Benzinger, MD, PhD
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Alzheimer's Disease, Mild Cognitive Impairment, Vascular Dementia, Fronto-temporal Dementia, Primary Progressive Aphasia, Parkinson' Disease Dementia, Mixed Dementia
Interventions
Not listed
Lead sponsor
Exonhit
Industry
Eligibility
21 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
3
States / cities
Las Vegas, Nevada • Cleveland, Ohio • Lakewood, Ohio
Completed No phase listed Observational Accepts healthy volunteers

Genetic Studies in Familial Dementia

NCT04680013
Conditions
Dementia of Alzheimer Type, Alzheimer Disease, Late Onset, Alzheimer Disease, Early Onset, Mild Cognitive Impairment, Dementia
Interventions
Not listed
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
4,884 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2024
U.S. locations
1
States / cities
Miami, Florida
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Daily Goal Setting to Increase Everyday Physical Activity and Promote Cognitive Health in Midlife

NCT05826379
Conditions
Physical Inactivity, Walking, Cognitive Health, Self-regulation, Overweight and Obesity
Interventions
Adaptive Daily Goal Setting, Interim Goal Prompt
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
30 Years to 70 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Hershey, Pennsylvania
Not listed Phase 1 Interventional Accepts healthy volunteers

BONSAI: Biomarkers of Nonsteroidal Anti-Inflammatories

NCT00239746
Conditions
Alzheimer's Disease
Interventions
Ibuprofen, Placebo
Drug
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
59 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2009
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Alzheimer's Disease
Interventions
Creatine Monohydrate
Dietary Supplement
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
60 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Kansas City, Kansas
Terminated No phase listed Observational Accepts healthy volunteers

Event-Related Potential (ERP) Components in Clinical Diagnosis

NCT05673759
Conditions
Alzheimer Disease, Dementia, Mild, Mild Cognitive Impairment
Interventions
Electroencephalogram (EEG) system, Standard Neuropsychological Testing, Additional neuropsychological tests
Device · Behavioral
Lead sponsor
Boston University
Other
Eligibility
20 Years to 90 Years
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Alzheimer's Disease
Interventions
PF-04447943, Placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
55 Years to 85 Years
Enrollment
191 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
22
States / cities
Northport, Alabama • Costa Mesa, California • Glendale, California + 18 more
Conditions
Alzheimer Disease, Mild Cognitive Impairment
Interventions
2-hydroxybenzylamine acetate, Placebo
Drug · Other
Lead sponsor
MTI Biotech Inc
Industry
Eligibility
55 Years to 85 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Alzheimer's Disease, Dementia
Interventions
A mix of natural treatments and medications
Other
Lead sponsor
Practitioners Alliance Network
Other
Eligibility
Not listed
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Kailua, Hawaii
Active, not recruiting Not applicable Interventional

Stress and Blood Pressure Management for Caregivers

NCT05734638
Conditions
Hypertension, Stress, Psychological
Interventions
MIM-DASH, MIM Only, DASH Only
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
40 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Depressive Symptoms, Anxiety Generalized
Interventions
Mobile Phone Application
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
17 Years to 20 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Alzheimer Disease
Interventions
[18F] MNI-558
Drug
Lead sponsor
Institute for Neurodegenerative Disorders
Other
Eligibility
55 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
New Haven, Connecticut
Not listed Not applicable Interventional Accepts healthy volunteers

Music-Based Interventions, Aging, Alzheimer's Disease

NCT06152211
Conditions
Speech Perception, Anxiety, Social Behavior
Interventions
Choir, Group Music Listening
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
65 Years and older
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Poor Quality Sleep, Caregiver Stress, Alzheimer's Disease (Incl Subtypes)
Interventions
Self-Administered Hypnosis, Self-Administered White Noise Hypnosis
Behavioral
Lead sponsor
Baylor University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Waco, Texas
Conditions
Caregiver Burden, Caregiver Stress Syndrome, Caregiver Burnout
Interventions
TBI-AD/ADRD Caregiver Support Intervention (TACSI)
Other
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years and older
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Alzheimer Disease
Interventions
Transcranial direct current stimulation (tDCS), Sham tDCS
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
60 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Alzheimer Dementia (AD)
Interventions
Intermittent deep brain stimulation of the nucleus basalis of Meynert
Device
Lead sponsor
Augusta University
Other
Eligibility
65 Years to 85 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Augusta, Georgia
Conditions
Dementia
Interventions
Lifestyle Intervention, Standard Health Education
Behavioral · Other
Lead sponsor
Healthy Minds Initiative
Other
Eligibility
55 Years to 85 Years
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Alzheimer Disease
Interventions
Spaced Retrieval Training
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
21 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2010
U.S. locations
1
States / cities
Little Rock, Arkansas
Conditions
Dementia, Dysphagia, Alzheimer Disease
Interventions
Isometric tongue strengthening facilitated by Iowa Oral Performance Instrument (IOPI), Biotene Oral Balance Gel
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
50 Years to 99 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Alzheimer's Disease
Interventions
Insulin glulisine, Saline
Drug
Lead sponsor
HealthPartners Institute
Other
Eligibility
65 Years to 85 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Saint Paul, Minnesota
Conditions
Dementia, Alzheimer Disease
Interventions
Skill Training Condition - problem solving training, REACH for TLC (Telephone Linked Computer) system
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
21 Years and older
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2001
U.S. locations
5
States / cities
Birmingham, Alabama • Menlo Park, California • Miami, Florida + 2 more
Conditions
Caregivers, Alzheimer's Disease
Interventions
Meditation, Education, Respite only
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
50 Years to 85 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Portland, Oregon