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Showing 1–24 of 844 matching trials from the live ClinicalTrials.gov search.
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Physical Activity and Leisure-time Study (PALS)

NCT01342471
Conditions
Physical Activity, Weight
Interventions
TV commercial stepping, 30-min walk
Behavioral
Lead sponsor
University of Tennessee
Other
Eligibility
25 Years to 65 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Knoxville, Tennessee
Conditions
Spinal Cord Injuries, Brown Sequard, Central Cord Syndrome
Interventions
Intermittent Hypoxia, Locomotor Training
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Gainesville, Florida
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Effects of Caffeine and Intermittent Hypoxia on Leg Function in Human Spinal Cord Injury

NCT02323698
Conditions
Spinal Cord Injuries
Interventions
Caffeine, AIH, Placebo, SHAM
Drug · Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Cambridge, Massachusetts
Conditions
Acute Pulmonary Embolism
Interventions
Healthy Living Intervention-1, Healthy Living Intervention-2
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Rochester, New York
Conditions
Cardiomyopathy, Hypertrophic, Cardiomyopathy, Hypertrophic, Familial
Interventions
Perhexiline, Use of bioanalytical assay to monitor plasma levels of perhexiline
Drug · Device
Lead sponsor
Heart Metabolics Limited
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
11
States / cities
Stanford, California • Indianapolis, Indiana • Baltimore, Maryland + 7 more
Completed Not applicable Interventional Results available

Improving Ambulation Post Stroke With Robotic Training

NCT00975156
Conditions
Stroke
Interventions
Physical Therapy, Lokomat
Other · Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 90 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Houston, Texas
Conditions
Advanced Cancers
Interventions
Fentanyl Pectin Nasal Spray, Placebo Nasal Spray, Walk Test, Questionnaires, Mental Ability Tests
Drug · Other · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Houston, Texas
Conditions
Hypertension, Stroke, Sedentary Lifestyle, Aged, Minority Groups
Interventions
Walking Intervention
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
60 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
4
States / cities
Los Angeles, California • Montebello, California • Watts, California
Conditions
Depression, Anxiety, Physical Activity, Time in Nature, Self-Efficacy, Feasibility Pilot Study
Interventions
Walk-and-talk therapy
Behavioral
Lead sponsor
Kansas State University
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Manhattan, Kansas
Not yet recruiting Not applicable Interventional

Study Comparing Osteoarthritis Programs

NCT07896473
Conditions
Osteoarthritis
Interventions
I'm Walking, Walk With Ease
Behavioral · Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
50 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Seattle, Washington
Conditions
PAH
Interventions
75mg CXA-10, 150mg CXA-10, Placebo
Drug · Other
Lead sponsor
Complexa, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
40
States / cities
Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 34 more
Conditions
Spinal Cord Injury (SCI), Gait
Interventions
NNP-LE
Device
Lead sponsor
Louis Stokes VA Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
2
States / cities
Cleveland, Ohio
Completed Not applicable Interventional

Heart Failure Insomnia Treatment Study

NCT03636880
Conditions
Heart Failure, Cardiac Failure, Congestive Heart Failure, Insomnia, Sleep Disorder, Sleep Initiation and Maintenance Disorders, Disorders of Initiating and Maintaining Sleep, Anxiety, Depression
Interventions
Brief treatment for Insomnia, Sleep Monitoring
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Stroke
Interventions
Robotic exoskeleton for walking assist
Device
Lead sponsor
College of St. Scholastica, Inc.
Other
Eligibility
18 Years to 85 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Duluth, Minnesota
Conditions
Transtibial Amputation, Transfemoral Amputation
Interventions
Conventional prosthetic socket, Adjustable Quatro socket
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Completed No phase listed Observational Accepts healthy volunteers

Cadence and Intensity Across the Adult Lifespan

NCT02650258
Conditions
Aging, Walking, Motor Activity, Activities of Daily Living
Interventions
treadmill walking
Behavioral
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
21 Years to 85 Years
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Charlotte, North Carolina
Completed Not applicable Interventional Results available

Ankle-foot Orthoses for Peripheral Artery Disease

NCT02280200
Conditions
Peripheral Artery Disease
Interventions
AFO to improve outcomes
Device
Lead sponsor
University of Minnesota
Other
Eligibility
40 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Missoula, Montana
Terminated Not applicable Interventional Accepts healthy volunteers

Everyday Activity Shoes: a Quantification of Impact Forces While Walking

NCT04197362
Conditions
Impact Forces
Interventions
Evaluation
Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Older Adults With Elevated Dementia Risk
Interventions
Mindfulness-based walking, Walking-only
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
60 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbia, South Carolina
Conditions
Peripheral Artery Disease, Intermittent Claudication
Interventions
ALD-301, Placebo (vehicle)
Biological
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
40 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
9
States / cities
Stanford, California • Gainesville, Florida • Miami, Florida + 5 more
Conditions
Amputation, Diabetes Complications
Interventions
Custom prosthetic socket with mechanical vibrators (stochastic resonance), Conventional prosthetic socket (current clinical practice)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Completed Not applicable Interventional

Post-operative Lite Run Study

NCT03135145
Conditions
Cerebral Palsy, Neurologic Disorder, Chromosome Abnormality, Spina Bifida
Interventions
Lite Run Gait Trainer, Usual Treatments
Device · Other
Lead sponsor
Gillette Children's Specialty Healthcare
Other
Eligibility
4 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Saint Paul, Minnesota
Completed No phase listed Observational

CHF Inpatient Ambulation Trial

NCT02828553
Conditions
Heart Failure
Interventions
Aggressive planned ambulation with a mobility aide
Other
Lead sponsor
Lancaster General Hospital
Other
Eligibility
18 Years and older
Enrollment
352 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Lancaster, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

The Metabolic Response of Unweighted Treadmill Walking

NCT07870434
Conditions
Metabolic Testing
Interventions
AlterG Treadmill, Metabolic Assessment
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 30 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
2
States / cities
East Meadow, New York • Garden City, New York