Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 8, 2026, 10:16 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 201 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Analgesics, Opioid Clear all

Conditions: Mastectomy; Lymphedema
Interventions: Cryoneurolysis, Sham Comparator; Device
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 216 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2028
U.S. locations: 5
States / cities: Los Angeles, California • San Diego, California • Gainesville, Florida + 2 more

Conditions: Postherpetic Neuralgia
Interventions: ADL5747, Placebo, Pregabalin; Drug
Lead sponsor: Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA); Industry
Eligibility: 18 Years to 75 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010
U.S. locations: 1
States / cities: West Palm Beach, Florida

Conditions: Prescription Drug Abuse
Interventions: MyHealthyChoices, Health Risk Assessment; Behavioral · Other
Lead sponsor: Johns Hopkins Bloomberg School of Public Health; Other
Eligibility: 18 Years and older
Enrollment: 123 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 2
States / cities: Baltimore, Maryland • Morgantown, West Virginia

Conditions: Pain, Low Back Pain
Interventions: BEMA Buprenorphine; Drug
Lead sponsor: BioDelivery Sciences International; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Marietta, Georgia

Conditions: Pain
Interventions: Not listed
Lead sponsor: Pearl Network; Network
Eligibility: Not listed
Enrollment: 2,773 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2014
U.S. locations: 1
States / cities: New York, New York

Conditions: Opioid Dependency
Interventions: Probuphine (buprenorphine implant); Drug
Lead sponsor: Titan Pharmaceuticals; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: North Miami, Florida

Conditions: Opioid Use, Spine Fusion
Interventions: Spinal Fusion Preoperative Opioid Taper, Non-taper Control; Behavioral · Other
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Redwood City, California

Conditions: Opioid Overdose
Interventions: Observation only; Other
Lead sponsor: Member Companies of the Opioid PMR Consortium; Industry
Eligibility: 18 Years to 79 Years
Enrollment: 808,455 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 4
States / cities: Wilmington, Delaware • Boston, Massachusetts • Portland, Oregon + 1 more

Conditions: Mammaplasty
Interventions: Breast Reconstruction (Mammaplasty), Pecs blocks, Exparel, Bupivacaine; Procedure · Device · Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Pain, Hip Fractures
Interventions: Femoral Nerve Block; Procedure
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 60 Years and older
Enrollment: 164 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2014
U.S. locations: 3
States / cities: New York, New York

Conditions: Fractures, Closed, Pain, Postoperative, Pain Catastrophizing, Pain, Acute, Analgesia, Opioid Use, Acceptance and Commitment Therapy, Orthopedics, Analgesics, Opioid, Text Messaging
Interventions: Acceptance and Commitment Therapy Delivered via an Automated Mobile Messaging Robot; Behavioral
Lead sponsor: Christopher Anthony; Other
Eligibility: 18 Years to 100 Years
Enrollment: 82 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Low Back Pain, Osteoarthritis, Neuropathic Pain
Interventions: EN3409; Drug
Lead sponsor: BioDelivery Sciences International; Industry
Eligibility: 18 Years and older
Enrollment: 304 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 57
States / cities: Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 52 more

Conditions: Surgical Procedure, Unspecified, Orthopedic Disorder
Interventions: Standardized instructions, Conventional instructions; Other
Lead sponsor: Giorgio Veneziano; Other
Eligibility: Up to 20 Years
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Opioid Pain Medication
Interventions: Tranexamic acid, Aminocaproic acid, Recombinant Human Thrombin, Lidocaine Hydrochloride with Epinephrine, Bupivacaine Hydrochloride with Epinephrine; Drug
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 99 Years
Enrollment: 46 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Colorectal Surgery, Pain, Postoperative, Analgesic, Opioid
Interventions: Morphine, Hydromorphone; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 75 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Pain, Postoperative
Interventions: Oral Gabapentin and Intravenous Acetaminophen (IV APAP), Opiate based pain regimen.; Drug
Lead sponsor: Inova Health Care Services; Other
Eligibility: 18 Years to 85 Years
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 1
States / cities: Falls Church, Virginia

Conditions: Postoperative Pain
Interventions: HTX-011, Luer lock applicator, Vial access device, Ibuprofen, Acetaminophen, Ketorolac; Drug · Device
Lead sponsor: Heron Therapeutics; Industry
Eligibility: 18 Years and older
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 5
States / cities: Anaheim, California • Pasadena, California • Draper, Utah + 2 more

Conditions: Tooth Extraction
Interventions: Clinical Decision Support, Patient education; Other
Lead sponsor: HealthPartners Institute; Other
Eligibility: 16 Years and older
Enrollment: 5,722 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Bloomington, Minnesota

Conditions: Moderate to Severe Postoperative Pain
Interventions: Q8003, Morphine sulfate, Oxycodone HCl; Drug
Lead sponsor: QRxPharma Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 522 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 5
States / cities: Anaheim, California • Owings Mills, Maryland • Pasadena, Maryland + 2 more

Conditions: Opioid Withdrawal
Interventions: Dexmedetomidine, Placebo; Drug
Lead sponsor: BioXcel Therapeutics Inc; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 225 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 3
States / cities: Miami Lakes, Florida • Marlton, New Jersey • New York, New York

Conditions: Opioid Dependence
Interventions: Probuphine (buprenorphine implant), Sublingual Buprenorphine; Drug
Lead sponsor: Titan Pharmaceuticals; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 1
States / cities: Fort Lauderdale, Florida

Conditions: Post Operative Pain
Interventions: OPIOID, NON-OPIOID; Drug
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 18 Years to 99 Years
Enrollment: 53 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 5
States / cities: Chicago, Illinois • Baltimore, Maryland • Ann Arbor, Michigan + 2 more

Conditions: Postoperative Pain
Interventions: Buprenorphine transdermal patch, Placebo BTDS; Drug
Lead sponsor: Purdue Pharma LP; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 5
States / cities: Phoenix, Arizona • San Clemente, California • Orlando, Florida + 2 more

Conditions: Computer + Fluency, Computer Only, Treatment as Usual
Interventions: Computer + Fluency, Computer Only, Treatment as Usual; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 1
States / cities: Baltimore, Maryland

Search by objective public record fields.

Ultrasound-Guided Percutaneous Cryoneurolysis to Treat Postoperative Pain After Mastectomy

Study to Assess the Efficacy, Safety, and Tolerability of ADL5747 in Participants With Postherpetic Neuralgia

Using m-Health Tools to Reduce the Misuse of Opioid Pain Relievers

Longterm Safety Study of BEMA Buprenorphine in Subjects With Chronic Low Back Pain

Analgesic Use and Effectiveness for Dental Procedures

Study of Probuphine in Patients With Opioid Dependence

Does Preoperative Pain Medication Management Influence Surgical Outcomes in Spinal Fusion

Incidence and Predictors of Opioid Overdose and Death Among Long-Term Users of Opioid Analgesics

The Use of Pecs Blocks in Combination With Exparel in Breast Reconstruction Surgery

Improving Pain and Function in Hip Fracture

Pain and Narcotic Usage After Orthopaedic Surgery

Long-term Open-Label Safety Study to Evaluate EN3409

Opioid Consumption After Knee Arthroscopy

Evaluating Postoperative Non-Opioid Pain Management Utilizing Local Anesthetics Coupled With Modulated Coagulation

Intrathecal Opioids for Colorectal Resection

Effectiveness of an Opioid Sparing Pain Regimen in Cardiac Surgery

Phase 2 Herniorrhaphy Study for Opioid Elimination

De-Implementing Opioids for Dental Extractions

Comparison of the Efficacy and Safety of Q8003 Versus Its Individual Components in Bunionectomy Patients

Dexmedetomidine in the Treatment of Symptoms Of Acute Opioid Withdrawal

A Bioavailability and Safety Study of Probuphine Versus Sublingual Buprenorphine in Patients With Opioid Dependence

Opioid Analgesic Reduction Study (OARS) - Pilot

Safety of Buprenorphine Transdermal System (BTDS) in Subjects With Acute Postoperative Pain After Total Knee Replacement

Evaluation of a Computerized Opioid Overdose Prevention Program