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ClinicalTrials.gov public records Last synced Oct 1, 2026, 11:35 AM EDT

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Showing 25–48 of 1,313 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Anesthesia, Dental Clear all
Completed Not applicable Interventional Results available

Comparison of the ToFscan and TetraGraph During Recovery of Neuromuscular Function in the Post Anesthesia Care Unit

NCT03920670
View directory record Official record
Conditions
Residual Neuromuscular Blockade
Interventions
TetraGraph (TG), ToFscan (TS)
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Jacksonville, Florida • Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 29, 2021 · Synced Oct 1, 2026, 11:35 AM EDT
Completed Phase 3 Interventional Results available

Evaluate the Use of Paravertebral Block in Reconstructive Breast Surgery

NCT00542542
View directory record Official record
Conditions
Breast Cancer
Interventions
Paravertebral Block, Propofol, Fentanyl, Ropivacaine, Midazolam
Procedure · Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 13, 2015 · Synced Oct 1, 2026, 11:35 AM EDT
Active, not recruiting Not applicable Interventional

Detecting Post-surgical Respiratory Compromise and Prompting Patients to Self-rescue: An Early Feasibility Study

NCT02962557
View directory record Official record
Conditions
Anesthesia
Interventions
NM3, Phillips Medical, Wallingford CT: verbal prompts to breathe with an optional shoulder shake
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 1, 2026, 11:35 AM EDT
Terminated Not applicable Interventional Results available

Anesthesia in Patients With Mitochondrial Disease

NCT02053766
View directory record Official record
Conditions
Mitochondrial Diseases
Interventions
Sevoflurane, Dexmedetomidine, Propofol
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
1 Day to 17 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 28, 2024 · Synced Oct 1, 2026, 11:35 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Anesthesia and Postoperative Pain

NCT00232817
View directory record Official record
Conditions
Postoperative Pain
Interventions
Nicotine (drug)
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2006
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 12, 2024 · Synced Oct 1, 2026, 11:35 AM EDT
Not yet recruiting Phase 2 Interventional

Study of Psilocybin Under Anesthesia Controlled by EEG

NCT07479550
View directory record Official record
Conditions
Major Depression
Interventions
Psilocybin (Usona Institute), Propofol, Placebo
Drug
Lead sponsor
Stanford University
Other
Eligibility
25 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 1, 2026, 11:35 AM EDT
Completed Phase 4 Interventional

A Safety and Efficacy Study of Dexmedetomidine in ICU Patients Requiring Continuous Sedation

NCT00216190
View directory record Official record
Conditions
Mechanically Ventilated and Intubated Subjects
Interventions
Dexmedetomidine HCL Injection, Midazolam Injection
Drug
Lead sponsor
Hospira, now a wholly owned subsidiary of Pfizer
Industry
Eligibility
18 Years and older
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
78
States / cities
Birmingham, Alabama • Chandler, Arizona • Phoenix, Arizona + 75 more
Source: ClinicalTrials.gov public record
Updated Jul 23, 2015 · Synced Oct 1, 2026, 11:35 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

EEG-Guided Analgesic Titration During General Anesthesia to Improve Early Neurocognitive Recovery in Older Patients

NCT04443517
View directory record Official record
Conditions
Postoperative Delirium
Interventions
Alpha Optimization, Emergence from anesthesia with Dexmedetomidine
Procedure · Behavioral
Lead sponsor
Columbia University
Other
Eligibility
60 Years and older
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 1, 2026, 11:35 AM EDT
Not yet recruiting Phase 4 Interventional

Effect of Albumin Versus Routine Care on Hemodynamic Response and Stability in Patients With Preeclampsia Guided by a Non-invasive Hemodynamic Monitoring System During Cesarean Delivery With Spinal Anesthesia

NCT06107335
View directory record Official record
Conditions
Pre-Eclampsia
Interventions
Human Albumin (colloid), Lactated Ringer's Injection (crystalloid), Edwards HemoSphere monitor with ClearSight-Acumen finger cuff
Drug · Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older · Female only
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 6, 2024 · Synced Oct 1, 2026, 11:35 AM EDT
Completed No phase listed Observational

Single Dose Pharmacokinetics and Pharmacodynamics of Bupivacaine Following Transversus Abdominis Plane (TAP) Block in Neonates

NCT01557985
View directory record Official record
Conditions
Postoperative Pain
Interventions
Bupivacaine
Drug
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
Up to 28 Days
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Oct 1, 2026, 11:35 AM EDT
Withdrawn Phase 1 Interventional Accepts healthy volunteers

Turning Dexmedetomidine Into a Powerful Anesthetic That Can be Rapidly and Completely Reversed

NCT04942340
View directory record Official record
Conditions
Emergence From Anesthesia
Interventions
Atipamezole & Caffeine, Dexmedetomidine Hydrochloride & Saline
Drug
Lead sponsor
University of Chicago
Other
Eligibility
22 Years to 39 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 17, 2023 · Synced Oct 1, 2026, 11:35 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Serum Bupivacaine Concentration Levels After Injection of Liposomal Bupivacaine Into the Knee

NCT02626559
View directory record Official record
Conditions
Anesthesia, Local
Interventions
liposomal bupivacaine/plain bupivacaine peri-articular injection
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 9, 2016 · Synced Oct 1, 2026, 11:35 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Safety and Pharmacokinetics of Kovacaine Nasal Spray in Pediatric Subjects

NCT01952990
View directory record Official record
Conditions
Anesthesia
Interventions
Tetracaine HCl 3% and Oxymetazoline HCl 0.05%
Drug
Lead sponsor
St. Renatus, LLC
Industry
Eligibility
3 Years to 17 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 8, 2015 · Synced Oct 1, 2026, 11:35 AM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers Results available

Topical Application of Cocaine HCl 4% and 10% on Safety and Efficacy in Local (Topical) Anesthesia

NCT01746940
View directory record Official record
Conditions
Diagnostic, Procedures and Surgeries on or Through Accessible Mucous Membranes, of the Nasal Cavities
Interventions
Cocaine HCl 4% Topical Solution, Cocaine HCl 10% Topical Solution, Placebo Topical Solution
Drug
Lead sponsor
Lannett Company, Inc.
Industry
Eligibility
18 Years and older
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
2
States / cities
Bridgeport, Connecticut • Plano, Texas
Source: ClinicalTrials.gov public record
Updated May 12, 2017 · Synced Oct 1, 2026, 11:35 AM EDT
Completed Not applicable Interventional

A Simple Clinical Maneuver to Reduce Laparoscopy Induced Shoulder Pain

NCT00575237
View directory record Official record
Conditions
Shoulder Pain
Interventions
Recruitment manouver
Procedure
Lead sponsor
Phelps, Paul, M.D.
Individual
Eligibility
15 Years to 65 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Wildomar, California
Source: ClinicalTrials.gov public record
Updated Dec 18, 2007 · Synced Oct 1, 2026, 11:35 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Total Intravenous Versus Inhalational Anesthesia- A Geriatric Anesthesia Study

NCT06036095
View directory record Official record
Conditions
Neurocognitive Disorders, Anesthesia, Post-operative Delirium, Post-operative Cognitive Dysfunction
Interventions
Sevoflurane, Propofol
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
70 Years to 110 Years
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 8, 2024 · Synced Oct 1, 2026, 11:35 AM EDT
Enrolling by invitation Phase 4 Interventional

Mepivacaine Versus Bupivacaine Onset Time in Ultrasound-guided Ankle Blocks

NCT05425979
View directory record Official record
Conditions
Ankle Block, Foot Surgery
Interventions
Mepivacaine, Bupivacaine
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 1, 2026, 11:35 AM EDT
Completed Not applicable Interventional

Lower Extremity Elevation to Minimize Hemodynamic Instability During Induction of General Anesthesia

NCT06513169
View directory record Official record
Conditions
Post Induction Hypotension
Interventions
Group 1: LEE
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 70 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Oct 1, 2026, 11:35 AM EDT
Completed Phase 4 Interventional Results available

Endotracheal Tube Holder and Bite Guard Research

NCT02347488
View directory record Official record
Conditions
Surgery, Anesthesia
Interventions
Haider ETT Tube Holder and Bite Guard, Tape
Device · Procedure
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Oct 1, 2026, 11:35 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Comparing Oxygen Saturation in Post Anesthesia Care Unit After Different Methods of Pain Relief

NCT00435383
View directory record Official record
Conditions
Cryptorchidism
Interventions
Not listed
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
1 Year to 6 Years · Male only
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 14, 2015 · Synced Oct 1, 2026, 11:35 AM EDT
Completed Not applicable Interventional Results available

An Anesthesia-Centered Bundle to Reduce Postoperative Pulmonary Complications: The PRIME-AIR Study

NCT04108130
View directory record Official record
Conditions
Postoperative Pulmonary Complications
Interventions
Preoperative Education, Intraoperative PEEP (Positive End-Expiratory Pressure) Individualization, Individualization of Neuromuscular Blockade, Postoperative Incentive Spirometry, Postoperative Ambulation
Other · Procedure · Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
794 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
16
States / cities
San Francisco, California • Stanford, California • Aurora, Colorado + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Oct 1, 2026, 11:35 AM EDT
Completed No phase listed Observational

Endobronchial Ultrasound Guided Transbronchial Needle Aspiration Performed Under General Anesthesia Versus Moderate Sedation

NCT01430962
View directory record Official record
Conditions
Mediastinal Lymphadenopathies, Mediastinal Masses, Hilar Lymphadenopathies
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 23, 2015 · Synced Oct 1, 2026, 11:35 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Validation of the REPS Prediction Tool

NCT03585400
View directory record Official record
Conditions
Residual Neuromuscular Blockade, Curarization, Postoperative Residual, Postoperative Respiratory Complication
Interventions
Observational Study
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
101,510 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 26, 2021 · Synced Oct 1, 2026, 11:35 AM EDT
Completed No phase listed Observational

Supraglottic Airway Needed To Achieve Ventilation

NCT05190757
View directory record Official record
Conditions
Airway Complication of Anesthesia, Difficult or Failed Intubation
Interventions
Airway and Ventilation
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 5, 2023 · Synced Oct 1, 2026, 11:35 AM EDT