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Showing 25–48 of 85 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional

PROMIS and Patient Satisfaction

NCT04654910
Conditions
Ankle Pathology, Foot Pathology
Interventions
PROMIS Score Explanation, Placebo
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
275 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Rochester, New York
Completed No phase listed Observational Accepts healthy volunteers

Cardiovascular Disease Biomarkers in Smokers and Moist Snuff Consumers

NCT01692353
Conditions
Cardiovascular Disease, Cigarette Smoking
Interventions
Subject's usual brand (UB) tobacco product
Other
Lead sponsor
R.J. Reynolds Tobacco Company
Industry
Eligibility
26 Years to 49 Years · Male only
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Lincoln, Nebraska
Conditions
Pareses, Lower Extremity
Interventions
C-Brace, KAFO/SCO
Device
Lead sponsor
Otto Bock Healthcare Products GmbH
Industry
Eligibility
18 Years and older
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
4
States / cities
Sarasota, Florida • Chicago, Illinois • Houston, Texas + 1 more
Conditions
Avascular Necrosis of the Talus, Talar Osteochondral Defect of Ankle, Talar Dysfunction
Interventions
Total Talus Replacement (TTR)
Device
Lead sponsor
Restor3D
Industry
Eligibility
22 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2031
U.S. locations
1
States / cities
Charlotte, North Carolina
Conditions
Accidental Falls, Fall Due to Loss of Equilibrium, High Risk of Falls Due to Mobility Limitation, Diabetes, Arthritis, Cancer, Peripheral Arterial Disease, Parkinson's Disease, End Stage Renal Failure on Dialysis
Interventions
MBB AFO, Control
Device · Other
Lead sponsor
Bijan Najafi, PhD
Other
Eligibility
65 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Houston, Texas
Conditions
Spinal Cord Injuries, Spastic Gait, Foot Drop
Interventions
Whole Body Vibration (WBV), Electrical Stimulation
Other
Lead sponsor
Shepherd Center, Atlanta GA
Other
Eligibility
18 Years to 85 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Plantar Fasciitis of Both Feet, Metatarsalgia, Morton Neuroma, Hallux Valgus Deformity, Low Back Pain, Knee Pain, Ankle Pain
Interventions
Arch supports
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Ankle Assistance and Resistance in Older Adults

NCT06284525
Conditions
Sarcopenia
Interventions
Ankle resistance and biofeedback
Device
Lead sponsor
Northern Arizona University
Other
Eligibility
65 Years to 85 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Flagstaff, Arizona
Conditions
Sensorimotor Gait Disorder, Neurologic Ambulation Disorder, Gait, Drop Foot, Poststroke Hemiparesis, Post-Cerebrovascular Accident (CVA) Hemiparesis
Interventions
Ness L300, Ankle-foot orthosis
Device
Lead sponsor
Bioness Inc
Industry
Eligibility
18 Years and older
Enrollment
197 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
11
States / cities
Downey, California • Long Beach, California • San Diego, California + 8 more
Conditions
Ankle Injuries, Foot Injuries and Disorders, Body Weight Changes
Interventions
Nutrition and Exercise Instruction
Behavioral
Lead sponsor
Nell Blake, DPM
Other
Eligibility
18 Years to 89 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Hershey, Pennsylvania
Conditions
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/or Foot, Disorder of Joint of Ankle and/or Foot, Complete Tear, Ankle and/or Foot Ligament, Pathological Fracture - Ankle and/or Foot, Loose Body in Joint of Ankle and/or Foot
Interventions
Not listed
Lead sponsor
Ochsner Health System
Other
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
New Orleans, Louisiana
Conditions
Nausea, Emesis
Interventions
Not listed
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 99 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Conditions
Sprain, Strain, Acute Soft Tissue Injury
Interventions
Topical Ketoprofen 10% Cream, Topical Placebo Cream
Drug
Lead sponsor
Imprimis Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
364 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Recruiting Not applicable Interventional

Ankle Robotics After Stroke

NCT04594837
Conditions
Foot Drop, Stroke, Hemiparesis
Interventions
PTR Physical Therapy while wearing Robot group (Phase II), Physical Therapy Only (Phase II), Cross over group for Physical Therapy n Sub-Acute group. (Phase II), Chronic Stroke Subjects to receive robotic gait training therapy.
Device · Other
Lead sponsor
NextStep Robotics Inc.
Industry
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Neuropathic Pain
Interventions
Not listed
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 85 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Even-Up to Minimize Secondary Site Pain For Ankle Fracture

NCT04164563
Conditions
Arthralgia, Trouble Balancing
Interventions
Even-Up
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Ankle Rheumatoid Arthritis, Arthritis of Ankle, Failure, Prosthesis
Interventions
Not listed
Lead sponsor
Exactech
Industry
Eligibility
21 Years and older
Enrollment
370 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2031
U.S. locations
2
States / cities
Jacksonville, Florida • Durham, North Carolina
Conditions
Ankle Sprain
Interventions
HKT-500 Ketoprofen Topical Patch, Placebo Patch
Drug · Other
Lead sponsor
Hisamitsu Pharmaceutical Co., Inc.
Industry
Eligibility
18 Years and older
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
30
States / cities
Birmingham, Alabama • Montgomery, Alabama • Anaheim, California + 26 more
Conditions
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/ or Foot, Complete Tear, Ankle and/or Foot Ligament, Pathological Fracture - Ankle and/or Foot, Loose Body in Joint of Ankle and/or Foot
Interventions
Not listed
Lead sponsor
Jose Soberon, MD
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
New Orleans, Louisiana
Conditions
Stroke, Hemiparesis, Lower Extremity Paresis
Interventions
Electrical stimulator
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years to 80 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Not listed Phase 4 Interventional Accepts healthy volunteers

Liposomal Bupivacaine With Dexamethasone for Foot Surgery

NCT06465992
Conditions
Foot Surgery, Ankle Surgery, Post Operative Pain, Popliteal Nerve Block
Interventions
Exparel 266 MG Per 20 ML Injection, Bupivacaine Hcl 0.75% Inj, Dexamethasone
Drug
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Post-surgical Pain, Total Knee Arthroplasty, Foot/Ankle Surgery, Catheterization for Postop Analgesia
Interventions
ropivacaine 0.2%
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
San Diego, California
Conditions
Foot Drop, Stroke, Hemiparesis
Interventions
AMBLE
Device
Lead sponsor
NextStep Robotics Inc.
Industry
Eligibility
21 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Results available

Foot and Ankle Post-operative Oedema Management Using Geko™

NCT04927234
Conditions
Surgery, Edema
Interventions
geko™ therapy
Device
Lead sponsor
Firstkind Ltd
Industry
Eligibility
18 Years and older
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Capitola, California