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Showing 25–48 of 257 matching trials from the live ClinicalTrials.gov search.
Conditions
Anterior Cruciate Ligament Reconstruction Rehabilitation
Interventions
Rehabilitation with Exercise and Psychological Support (REPS)
Behavioral
Lead sponsor
HealthPartners Institute
Other
Eligibility
15 Years to 25 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Bloomington, Minnesota
Conditions
Knee Injuries
Interventions
OMS103HP, Vehicle
Drug
Lead sponsor
Omeros Corporation
Industry
Eligibility
15 Years to 65 Years
Enrollment
326 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
15
States / cities
Encinitas, California • Denver, Colorado • Englewood, Colorado + 12 more
Conditions
Anterior Cruciate Ligament Reconstruction
Interventions
interACTION, Standard of Care Physical Therapy
Device · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
15 Years to 30 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Pain, Postoperative, ACL
Interventions
OxyCODONE 5 mg Oral Tablet, Naproxen 500 Mg, Tylenol Pill, Liposomal bupivacaine, Femoral Nerve Catheter
Drug · Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
154 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Anterior Cruciate Ligament Injuries
Interventions
post-surgical functional bracing
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
14 Years to 39 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Terminated Not applicable Interventional

ACL Bone Health and Loading Study

NCT04682392
Conditions
ACL Tear
Interventions
Delfi's PTS Personalized Tourniquet System for Blood Flow Restriction Group, Standard ACL rehab
Device · Other
Lead sponsor
Candice Dunkin, MS, LAT, ATC
Other
Eligibility
16 Years to 22 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Fort Wayne, Indiana
Conditions
Anterior Cruciate Ligament (ACL) Reconstruction Surgery
Interventions
Arm 1-Kronos brace, Arm 2-Breg T-Scope brace
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
ACL Tear, Post Operative Pain
Interventions
Iovera, Celecoxib, Acetaminophen, Oxycodone, Tramadol, Bupivacaine Hydrochloride, Acetaminophen 500Mg Cap
Device · Drug
Lead sponsor
Matthew Varacallo
Other
Eligibility
15 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
DuBois, Pennsylvania
Conditions
Anterior Cruciate Ligament, Injury
Interventions
ACL reconstruction
Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 70 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Acute Injury of Anterior Cruciate Ligament
Interventions
Perturbation, Control
Other
Lead sponsor
Lynn Snyder-Mackler
Other
Eligibility
13 Years to 55 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Newark, Delaware
Completed Not applicable Interventional Results available

Anterior Cruciate Ligament Reconstruction and Plyometric Exercise

NCT01851655
Conditions
Anterior Cruciate Ligament Reconstruction
Interventions
Plyometric Exercise
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
15 Years to 30 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Interventions
Autologous Bone Marrow Derived Mesenchymal Stem Cells, Sham incision
Device · Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
ACL Injury
Interventions
Autologous bone grafting, Absence of autologous bone grafting
Procedure
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
3
States / cities
Hartford, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers

Medipore Tape Study

NCT02676115
Conditions
Scarring
Interventions
Standard Post Operative Skin Care, Medipore Tape
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
15 Years to 95 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Withdrawn Not applicable Interventional

Dynamic ACL Brace: In Vivo Kinematics

NCT03670550
Conditions
ACL Injury, ACL - Anterior Cruciate Ligament Rupture, ACL, ACL - Anterior Cruciate Ligament Deficiency
Interventions
Ossur Rebound ACL Brace
Device
Lead sponsor
Steadman Philippon Research Institute
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Vail, Colorado
Conditions
ACL Injury
Interventions
Telerehabilitation Therapy, In-person Rehabilitation Therapy
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 40 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

External Focus of Attention Feedback to Reduce Risk of Non-contact ACL Injury

NCT04914689
Conditions
Anterior Cruciate Ligament Injuries
Interventions
Internal focus of attention feedback, Visual internal focus of attention feedback, Auditory external focus of attention feedback
Other
Lead sponsor
University of North Carolina, Charlotte
Other
Eligibility
18 Years to 35 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Charlotte, North Carolina
Conditions
ACL Injury
Interventions
Blood Flow Restriction (BFR) therapy, Standard REHAB
Other
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
15 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Anterior Cruciate Ligament Rupture
Interventions
BioCleanse Tibialis tendon
Other
Lead sponsor
RTI Surgical
Industry
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Phoenix, Arizona
Completed Not applicable Interventional Results available

Optimizing Movement After Anterior Cruciate Ligament Injury

NCT05363683
Conditions
Anterior Cruciate Ligament Injuries, Knee Osteoarthritis
Interventions
Squat Biofeedback, Standard Care
Procedure
Lead sponsor
University of Nebraska
Other
Eligibility
13 Years to 35 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Omaha, Nebraska
Conditions
Anterior Cruciate Ligament Tear
Interventions
Ropivacaine injection
Drug
Lead sponsor
Sujana Dontukurthy
Other
Eligibility
Up to 21 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Columbus, Ohio
Completed No phase listed Observational Accepts healthy volunteers

Hormone Induced Effects on Ligament Laxity and Lower Extremity Motor Control

NCT04055129
Conditions
Hormone Influence on Ligament Laxity and Motor Control
Interventions
No interventions
Other
Lead sponsor
University of St. Augustine for Health Sciences
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Marcos, California
Conditions
Anterior Cruciate Ligament Tear
Interventions
ACL Reconstruction (Bone Patellar Tendon Bone Graft), Bridge Enhanced ACL Restoration (BEAR)
Procedure · Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 55 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
6
States / cities
Boulder, Colorado • Bloomington, Minnesota • Cleveland, Ohio + 3 more
Terminated Early Phase 1 Interventional Accepts healthy volunteers

Continuous Vs Single Shot Block After ACL

NCT04101682
Conditions
ACL Injury
Interventions
Bupivacaine
Drug
Lead sponsor
Northwell Health
Other
Eligibility
16 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Plainview, New York