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Showing 25–48 of 139 matching trials from the live ClinicalTrials.gov search.
Conditions
ACL Tears
Interventions
Anterior cruciate ligament reconstruction with BioBrace® augmentation, Arthroscopic anterior cruciate ligament reconstruction
Device · Procedure
Lead sponsor
CONMED Corporation
Industry
Eligibility
14 Years to 70 Years
Enrollment
500 participants
Timeline
2025 – 2030
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Anterior Cruciate Ligament Injury
Interventions
Neuromuscular Electrical Stimulation (NMES), Eccentric Exercise (ECC), Neuromuscular Electrical Stimulation (NMES) placebo, Eccentric Exercise (ECC) placebo
Device · Other
Lead sponsor
University of Michigan
Other
Eligibility
14 Years to 45 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
2
States / cities
Ann Arbor, Michigan
Conditions
Rupture of Anterior Cruciate Ligament
Interventions
Bupivacaine, Preservative free normal saline
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 70 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
ACL Reconstruction
Interventions
Methyl Prednisolone (MP), Standard Post-Operative Pain Control, Surgeon's Standard ACL Postoperative Regimen
Drug · Combination Product
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
14 Years to 65 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Anterior Cruciate Ligament Injuries
Interventions
Graded Exposure and Mindfulness Meditation, Waitlist Control
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
14 Years to 35 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed No phase listed Observational Accepts healthy volunteers

Gabapentin Premedication for ACL Reconstruction: RCT

NCT03417479
Conditions
Anterior Cruciate Ligament (ACL) Reconstruction
Interventions
Gabapentin
Other
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
12 Years to 18 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Interventions
Autologous Bone Marrow Derived Mesenchymal Stem Cells, Sham incision
Device · Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Knee Injuries
Interventions
Physical Therapy
Other
Lead sponsor
Twin Cities Orthopedics
Other
Eligibility
14 Years to 59 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2028
U.S. locations
1
States / cities
Edina, Minnesota
Completed Phase 4 Interventional Results available

iPACK for Post-op Pain Following ACL Reconstruction

NCT05498870
Conditions
ACL Injury, Post Operative Pain
Interventions
Adductor Canal Block (ACB) Only, Adductor Canal Block (ACB) + iPACK Block
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
12 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Anterior Cruciate Ligament Reconstruction
Interventions
silk fibroin-based incision dressing, cyanoacrylate-based closure system
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
14 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Results available

Blood Flow Restriction Following ACL Reconstruction

NCT03758755
Conditions
Anterior Cruciate Ligament Rupture
Interventions
Blood Flow Restriction Therapy, ACL Reconstruction rehabilitation
Device · Other
Lead sponsor
Inova Health Care Services
Other
Eligibility
13 Years to 50 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Fairfax, Virginia
Conditions
Anterior Cruciate Ligament Reconstruction
Interventions
OMS103HP, Vehicle
Drug
Lead sponsor
Omeros Corporation
Industry
Eligibility
17 Years to 65 Years
Enrollment
480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
10
States / cities
Los Angeles, California • Redwood City, California • Denver, Colorado + 7 more
Conditions
Pain
Interventions
Marcaine 0.25 % Injectable Solution
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
16 Years and older
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
Post-operative Pain, Quadriceps Muscle Strength
Interventions
Adductor Canal Block, Femoral Nerve Block, Ultrasound, Stimuplex A needle, local anaesthetic injection, Steroid Drug
Procedure · Device · Drug
Lead sponsor
Akron Children's Hospital
Other
Eligibility
8 Years to 18 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Akron, Ohio
Conditions
Anterior Cruciate Ligament Injury
Interventions
Operant Conditioning, Control, Single Pulse Transcranial Magnetic Stimulation
Behavioral · Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 45 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Anterior Cruciate Ligament Rupture
Interventions
BioCleanse Tibialis tendon
Other
Lead sponsor
RTI Surgical
Industry
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Phoenix, Arizona
Conditions
ACL Injury, ACL Reconstruction, Scar Formation
Interventions
Losartan, Placebo
Drug · Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Anterior Cruciate Ligament Tear
Interventions
ACL Reconstruction with Hybrid Remnant Repair, ACL Reconstruction without Hybrid Remnant Repair
Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
13 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
ACL - Anterior Cruciate Ligament Deficiency, ACL Injury, ACL Tear
Interventions
Patients undergoing ACL reconstruction with or without a tourniquet
Procedure
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Charlotte, North Carolina
Conditions
Knee Injuries
Interventions
OMS103HP, Vehicle
Drug
Lead sponsor
Omeros Corporation
Industry
Eligibility
15 Years to 65 Years
Enrollment
326 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
15
States / cities
Encinitas, California • Denver, Colorado • Englewood, Colorado + 12 more
Conditions
Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction Rehabilitation
Interventions
Joint Manipulation
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Pain and Anterior Cruciate Ligament Reconstruction
Interventions
Dry needling and STM
Other
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
18 Years to 40 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
West Point, New York
Completed Not applicable Interventional

On-Q Catheter Caregiver Education

NCT03372889
Conditions
Anterior Cruciate Ligament Injury, Pain; Catheter (Other), Satisfaction, Personal
Interventions
Patient educaiton materials - Print based, Patient educaiton materials - Media based
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
Not listed
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Anterior Cruciate Ligament, Injury
Interventions
ACL reconstruction
Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 70 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Portland, Oregon