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ClinicalTrials.gov public records Last synced Oct 6, 2026, 6:11 PM EDT

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Showing 25–48 of 52 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Anterior Knee Pain Syndrome Clear all
Recruiting Not applicable Interventional

Emovi 3D Knee Assessment Device Intervention for Operational Readiness

NCT06517056
View directory record Official record
Conditions
Patellofemoral Pain, Patellofemoral Pain Syndrome
Interventions
Emovi Knee Kinesiography
Device
Lead sponsor
Womack Army Medical Center
Federal
Eligibility
18 Years to 50 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Honolulu, Hawaii • Fort Liberty, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 16, 2025 · Synced Oct 6, 2026, 6:11 PM EDT
Completed Not applicable Interventional

Mindful Miles Pilot Feasibility Study

NCT07462429
View directory record Official record
Conditions
Patellofemoral Pain, PFP, Patellofemoral Pain Syndrome, Patellofemoral Pain, Patellofemoral Pain (PFPS)
Interventions
Progressive Mindful Physical Activity
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 6, 2026, 6:11 PM EDT
Completed Not applicable Interventional

The Evaluation of a Novel Treatment Algorithm for Patients With Patellofemoral Syndrome

NCT01767246
View directory record Official record
Conditions
Patellofemoral Syndrome
Interventions
PFS Algorithm treatment, Multimodal treatment
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
12 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
2
States / cities
Columbus, Ohio • Westerville, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 7, 2015 · Synced Oct 6, 2026, 6:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing Rehabilitation Programs for Patellofemoral Pain Syndrome

NCT00445224
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
Hip Progressive Resistive Exercise, Quad Progressive Resistive Exercises
Other
Lead sponsor
Timothy Uhl
Other
Eligibility
15 Years to 35 Years · Female only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 28, 2017 · Synced Oct 6, 2026, 6:11 PM EDT
Terminated Not applicable Interventional

Blood Flow Restriction Therapy in Patellofemoral Pain Syndrome

NCT03717532
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
Placebo, Personalized Tourniquet System for Blood Flow Restriction
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 28, 2020 · Synced Oct 6, 2026, 6:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Conventional Home Exercise Programs Versus Electronic Home Exercise Versus Artificial Intelligence "Virtual Therapy" for Anterior Knee Pain

NCT01696162
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
Algorithm based Exercise Videos, PDF Exercise Sheets, Limited Exercise Videos
Other
Lead sponsor
Simpletherapy
Industry
Eligibility
18 Years to 64 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 17, 2014 · Synced Oct 6, 2026, 6:11 PM EDT
Recruiting Not applicable Interventional

The Effects of Dry Needling on Patients With Knee Pain

NCT02890485
View directory record Official record
Conditions
Patellofemoral Pain Syndrome, Anterior Knee Pain Syndrome
Interventions
Dry Needling, Sham Dry Needling, Physical Therapy
Device · Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 40 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2030
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 6, 2026, 6:11 PM EDT
Completed Not applicable Interventional

Comparison Study of Two Chiropractic Treatment Protocols for Knee Pain Due to Patellofemoral Pain Syndrome

NCT00401050
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
chiropractic manipulative therapy, knee exercises, Graston Instrument Soft Tissue Mobilization (GISTM)
Procedure
Lead sponsor
Cleveland Chiropractic College
Other
Eligibility
18 Years to 45 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 20, 2010 · Synced Oct 6, 2026, 6:11 PM EDT
Completed Not applicable Interventional

Strength Training in Female Runners With Patellofemoral Pain

NCT04480528
View directory record Official record
Conditions
Patellofemoral Syndrome
Interventions
Blood Flow Restriction Training (BFRT), Sham Blood Flow Restriction Training (Sham BFRT)
Other
Lead sponsor
Lauren Erickson
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 4, 2022 · Synced Oct 6, 2026, 6:11 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Internet Enhanced, Patient-Centered Orthopedic Care: A Prospective, Randomized, Controlled Pilot Trial

NCT02025400
View directory record Official record
Conditions
Knee Injuries, Shoulder Injuries, Rotator Cuff Disease, Meniscus Tear, Patellofemoral Pain
Interventions
eRehab, Formal Physical Therapy
Other
Lead sponsor
Charlotte Sports Medicine Institute, PA
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
2
States / cities
Prince Frederick, Maryland • Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 1, 2014 · Synced Oct 6, 2026, 6:11 PM EDT
Terminated Not applicable Interventional

Manual Therapy to Treat Gluteus Medius Trigger Points

NCT02333617
View directory record Official record
Conditions
Anterior Knee Pain Syndrome, Patellofemoral Pain Syndrome
Interventions
Dry Needling, Soft Tissue Mobilization, Placebo Control, Hip and core strengthening exercises
Other
Lead sponsor
Mitchell Selhorst
Other
Eligibility
13 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 24, 2018 · Synced Oct 6, 2026, 6:11 PM EDT
Recruiting Phase 3 Interventional

Comparing the Outcome of Electrical Stimulation and Physical Therapy in Patellofemoral Pain Syndrome

NCT03184545
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
EMS, Physical therapy
Device · Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 40 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 3, 2024 · Synced Oct 6, 2026, 6:11 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

MRI Study of Musculoskeletal Function

NCT00051857
View directory record Official record
Conditions
Abnormalities, Imaging, Patellofemoral Pain Syndrome
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
5 Years to 95 Years
Enrollment
750 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2003
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 6, 2026, 6:11 PM EDT
Completed No phase listed Observational Results available

In Vivo Arthroscopic Behavior of the Infrapatellar Plica of the Knee

NCT00643487
View directory record Official record
Conditions
Anterior Knee Pain Syndrome
Interventions
observation of the behavior of the infrapatellar plica
Procedure
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 80 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Apr 24, 2018 · Synced Oct 6, 2026, 6:11 PM EDT
Completed Not applicable Interventional Results available

Randomized Evaluation of the Efficacy of Synvisc-One® for the Treatment of Patellofemoral Chondromalacia

NCT01771952
View directory record Official record
Conditions
Chondromalacia Patella, Patellofemoral Pain Syndrome
Interventions
Synvisc-One™, Sham Treatment
Device · Other
Lead sponsor
University of Virginia
Other
Eligibility
15 Years to 45 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 4, 2020 · Synced Oct 6, 2026, 6:11 PM EDT
Terminated Early Phase 1 Interventional

Neural Mechanisms of Muscle Control in Individuals With Knee Pain

NCT02854774
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
Muscle activation exercises
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 5, 2020 · Synced Oct 6, 2026, 6:11 PM EDT
Recruiting Not applicable Interventional

Evaluating the Effectiveness of Clinical Practice Guideline Adherence for Patellofemoral Pain

NCT06665204
View directory record Official record
Conditions
Patellofemoral Pain
Interventions
Clinical Practice Guideline-adherent Care, Usual Care
Other
Lead sponsor
Sara Gorczynski, PT, DPT
Federal
Eligibility
18 Years and older
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 6, 2026, 6:11 PM EDT
Completed Not applicable Interventional

Effect of Lower Back Treatment in People With Patellofemoral Pain Syndrome.

NCT01975311
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
Lumbopelvic Manipulation, Passive lumbar spine flexion and extension
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 50 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 12, 2015 · Synced Oct 6, 2026, 6:11 PM EDT
Completed No phase listed Observational

Muscle Strength Loss and Its Effect on Knee Cap Motion in Volunteers With Anterior Knee Pain

NCT01862731
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 55 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 6, 2026, 6:11 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Limited Ankle Dorsiflexion and Effect on Single Limb Squats in Individuals With Patellofemoral Pain

NCT05285007
View directory record Official record
Conditions
Patellofemoral Pain
Interventions
Mobilization with Movement, No mobilization with movement and education
Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 59 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 6, 2026, 6:11 PM EDT
Completed Not applicable Interventional

Trial of Neurostimulation and Blood Flow Restriction for PFPS in Active Duty

NCT04086615
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
NMES and exercise supplemented with high BFR, NMES and exercise supplemented with low BFR
Device
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years to 44 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Fort Campbell North, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 6, 2022 · Synced Oct 6, 2026, 6:11 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Bilateral Knee Pain and Dry Needling

NCT05976269
View directory record Official record
Conditions
Patellofemoral Pain
Interventions
Dry needling
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 40 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2030
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 6, 2026, 6:11 PM EDT
Terminated Not applicable Interventional

Knee Isometric Program (KIP) Home Exercise Programs (HEP) Physical Therapy (PT) Study

NCT06536426
View directory record Official record
Conditions
Anterior Knee Pain Syndrome
Interventions
Knee Isometric Program (KIP)
Behavioral
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Oct 6, 2026, 6:11 PM EDT
Completed Not applicable Interventional Results available

Trial of Self-managed Approaches for Patellofemoral Pain Syndrome in Active Duty

NCT02597673
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
Home Exercise Program (HEP), NMES, TENS
Other · Device
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years to 45 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Fort Campbell North, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 1, 2020 · Synced Oct 6, 2026, 6:11 PM EDT