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ClinicalTrials.gov public records Last synced Nov 14, 2026, 10:44 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 680 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Antibiotic Therapy Clear all

Conditions: Gram-negative Bacterial Infections
Interventions: Not listed
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2017
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Respiratory Infections
Interventions: Physician & patient education on appropriate antibiotic use, Rapid C-reactive protein testing to guide antibiotic treatment; Behavioral · Procedure
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2007
U.S. locations: 9
States / cities: San Diego, California • Augusta, Georgia • Hines, Illinois + 6 more

Conditions: Bacterial Infection
Interventions: Not listed
Lead sponsor: University of California, Irvine; Other
Eligibility: 18 Years and older · Male only
Enrollment: 136 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2014
U.S. locations: 3
States / cities: Irvine, California • Long Beach, California • Orange, California

Conditions: Open Fracture
Interventions: Vancomycin; Drug
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years to 89 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2028
U.S. locations: 2
States / cities: San Antonio, Texas

Conditions: Obesity, Obesity, Morbid, Pregnancy, Infection; Cesarean Section
Interventions: Cefazolin; Drug
Lead sponsor: MemorialCare Health System; Other
Eligibility: Female only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 2
States / cities: Long Beach, California • Orange, California

Conditions: Paranasal Sinus Disease
Interventions: Bacitracin; Drug
Lead sponsor: Steward St. Elizabeth's Medical Center of Boston, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 226 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Brighton, Massachusetts

Conditions: Pouchitis
Interventions: AST-120; Drug
Lead sponsor: Ocera Therapeutics; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Rhinosinusitis
Interventions: Laser + ICG, Laser only; Device
Lead sponsor: New York Head & Neck Institute; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 3
States / cities: New York, New York

Conditions: Preterm Premature Rupture of Membrane, Pregnancy, High Risk, Preterm Birth
Interventions: Ceftriaxone 1000 MG, Clarithromycin 500mg, Metronidazole 500 mg, Ampicillin 2 GM Injection, Amoxicillin 250 MG, Azithromycin, Erythromycin; Drug
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 2
States / cities: Columbus, Ohio • Galveston, Texas

Conditions: Clostridium Enterocolitis, Pseudomembranous Colitis, Antibiotic-Associated Colitis
Interventions: Not listed
Lead sponsor: Michael E. DeBakey VA Medical Center; Federal
Eligibility: 18 Years and older
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Appendicitis
Interventions: Cefoxitin, Ertapenem, Moxifloxacin, Tigecycline, Ticarcillin-Clavulanic Acid; Metronidazole plus Cefazolin, Cefuroxime, Ceftriaxone, Cefotaxime, Ciprofloxacin, or Levofloxacin, Appendectomy; Drug · Procedure
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 1,552 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 25
States / cities: Sylmar, California • Torrance, California • Aurora, Colorado + 14 more

Conditions: Pneumonia
Interventions: Antibiotic stewardship messaging; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 643 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Complicated Intra-Abdominal Infection
Interventions: CAZ-AVI, Metronidazole, Meropenem; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 493 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 4
States / cities: Chula Vista, California • San Diego, California • St Louis, Missouri + 1 more

Conditions: Acne
Interventions: Duac, Ziana gel; Drug
Lead sponsor: Stiefel, a GSK Company; Industry
Eligibility: 12 Years and older
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 2
States / cities: Louisville, Kentucky • Mason, Ohio

Conditions: Prosthetic Joint Infection, Debridement With Prosthesis Retention, Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee, Suture
Interventions: VICRYL™ Plus (Coated VICRYL™ Plus Antibacterial), Polydioxanone (PDS™ II ) Sterile Synthetic Absorbable Surgical Suture-Monofilament; Device
Lead sponsor: University of Miami; Other
Eligibility: 18 Years to 89 Years
Enrollment: 142 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Appendicitis
Interventions: antibiotic duration; Other
Lead sponsor: University of Louisville; Other
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 2
States / cities: Louisville, Kentucky

Conditions: Pneumonia, Radiographic Lung Infiltrates
Interventions: Procalcitonin level, caregiver informed; Other
Lead sponsor: Winthrop University Hospital; Other
Eligibility: 18 Years and older
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Mineola, New York

Conditions: Surgical Site Infection
Interventions: Intrasite Vancomycin, IV Vancomycin; Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Infection, Soft Tissue, Infection, Wound, Cellulitis, Diabetic Foot Ulcer
Interventions: Cefazolin, Silberg Tissue Preparation System; Drug · Device
Lead sponsor: Sonescence, Inc.; Industry
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
U.S. locations: 1
States / cities: Sebastopol, California

Conditions: Bacteremia
Interventions: Daptomycin, Vancomycin, Ceftaroline; Drug
Lead sponsor: Sharp HealthCare; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 2
States / cities: La Mesa, California • San Diego, California

Conditions: Vancomycin-Resistant Enterococcus, Extended-Spectrum Beta Lactamase-Producing Enterobacteriaceae, or Carbapenem-Resistant Enterobacteriaceae Colonized Subjects
Interventions: KB109, No intervention; Other
Lead sponsor: Kaleido Biosciences; Industry
Eligibility: 18 Years and older
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 8
States / cities: Torrance, California • Atlanta, Georgia • Augusta, Georgia + 5 more

Conditions: Blepharitis
Interventions: ISV-502 (1.0% azithromycin and 0.1% dexamethasone combined), Azasite, Dexamethasone, Vehicle; Drug · Other
Lead sponsor: Sun Pharmaceutical Industries Limited; Industry
Eligibility: 18 Years and older
Enrollment: 917 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 45
States / cities: Chandler, Arizona • Phoenix, Arizona • Glendale, California + 36 more

Conditions: Acute Respiratory Infection
Interventions: Integrated clinical prediction rule (iCPR) system (iCPR); Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 347 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 3
States / cities: New York, New York • Salt Lake City, Utah • Madison, Wisconsin

Conditions: Infectious Disease
Interventions: Visualization tool; Other
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 273 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: Boston, Massachusetts

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Piperacillin as a Part of Antibiotic Streamlining in the Intensive Care Unit

Improving Antibiotic Use in Acute Care Treatment

Incidence of Antibiotic Resistant E.Coli in Patients Undergoing Repeat Prostate Biopsy

Placement of Antibiotic Powder in Wounds During the Emergency Room

Increased Cefazolin During Cesarean Delivery in Obese Population

Effectiveness of Antibiotic Delivery Via Bio-absorbable Sponge

Safety and Efficacy of AST-120 in the Treatment of Antibiotic-Refractory Pouchitis

Laser Assisted Treatment of Chronic Sinusitis With and Without Light Activated Agents

Improvement of PPROM Management With Prophylactic Antimicrobial Therapy (iPROMPT)

Vancomycin vs. Nitazoxanide to Treat Recurrent C. Difficile Colitis

The Comparison of Outcomes of Antibiotic Drugs and Appendectomy (CODA) Trial

Decreasing Unnecessary Antibiotics Prescribed for Possible Pneumonia Despite Normal Respiratory Rate and Oxygenation

Compare Ceftazidime-Avibactam + Metronidazole Versus Meropenem for Hospitalized Adults With Complicated Intra-Abdominal Infections

Comparative Antimicrobial Efficacy of Two Topical Acne Therapies for the Treatment of Facial Acne

Antibiotic-coated Braided Suture Study

Complex and Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure (CASA RELAX)

Use Of Procalcitonin Level For Guidance of The Treatment of Suspected Community Acquired Pneumonia

Dose Escalation Trial of Intrasite Vancomycin Pharmacokinetics

Direct Antibiotic Delivery of Cefazolin Into Soft Tissue Infections Using Subcutaneous Injection and Ultrasonic Dispersion

IL-10 Stratifying Tool for Towards Antibiotic Selection for MRSaB

VITORA: Clinical Study to Evaluate the Effect of KB109 on the Gut Microbiome in Subjects Whose Gastrointestinal Tracts Are Colonized With Multiple Drug-resistant Organisms

Efficacy and Safety Study of a Steroid/Antibiotic Combination Eyedrop to Treat Non-Bacterial Blepharitis

Decreasing Antibiotic Prescribing in Acute Respiratory Infections Through Nurse Driven Clinical Decision Support

Clinical Decision Support Tools for Antibiotic Prescribing